Q6NVF9: Cleavage and polyadenylation specificity factor subunit 6 {ECO:0000250|UniProtKB:Q16630}

General Information

Protein names	- Cleavage and polyadenylation specificity factor subunit 6 {ECO:0000250\|UniProtKB:Q16630}
Gene names	Cpsf6
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6NVF9

3 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MADGVDHIDI YADVGEEFNQ EAEYGGHDQI DLYDDVISPS ANNGDAPEDR DYMDTLPPTV
        70         80         90        100        110        120
GDDVGKGAAP NVVYTYTGKR IALYIGNLTW WTTDEDLTEA VHSLGVNDIL EIKFFENRAN
       130        140        150        160        170        180
GQSKGFALVG VGSEASSKKL MDLLPKRELH GQSPVVTPCN KQFLSQFEMQ SRKTTQSGQM
       190        200        210        220        230        240
SGEGKAGPPG GGSRAAFPQG GRGRGRFPGA VPGGDRFPGP AGPGGPPPPF PAGQTPPRPP
       250        260        270        280        290        300
LGPPGPPGPP GPPPPGQVLP PPLAGPPNRG DRPPPPVLFP GQPFGQPPLG PLPPGPPPPV
       310        320        330        340        350        360
PGYGPPPGPP PPQQGPPPPP GPFPPRPPGP LGPPLTLAPP PHLPGPPPGA PPPAPHVNPA
       370        380        390        400        410        420
FFPPPTNSGM PTSDSRGPPP TDPYGRPPPY DRGDYGPPGR EMDTARTPLS EAEFEEIMNR
       430        440        450        460        470        480
NRAISSSAIS RAVSDASAGD YGSAIETLVT AISLIKQSKV SADDRCKVLI SSLQDCLHGI
       490        500        510        520        530        540
ESKSYGSGSR RERSRERDHS RSREKSRRHK SRSRDRHDDY YRERSRERER HRDRDRDRDR
       550
ERDREREYRH R

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

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Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q6NVF9-1-unknown	MADGVD...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6NVF9-55-unmodified	TLPPTV...	55		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q6NVF9-64-unknown	VGKGAA...	64	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC32473

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TVGDDV	63	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32473
...LTWWTT	92	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000135848
...EYRHR	551	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_MOUSE	63	GDDV.\|.VGKG	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)