P68373: Tubulin alpha-1C chain

General Information

Protein names	- Tubulin alpha-1C chain - Alpha-tubulin 6 - Alpha-tubulin isotype M-alpha-6 - Tubulin alpha-6 chain - Detyrosinated tubulin alpha-1C chain
Gene names	Tuba1c
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P68373

11 N-termini

10 C-termini

10 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MRECISIHVG QAGVQIGNAC WELYCLEHGI QPDGQMPSDK TIGGGDDSFN TFFSETGAGK
        70         80         90        100        110        120
HVPRAVFVDL EPTVIDEVRT GTYRQLFHPE QLITGKEDAA NNYARGHYTI GKEIIDLVLD
       130        140        150        160        170        180
RIRKLADQCT GLQGFLVFHS FGGGTGSGFT SLLMERLSVD YGKKSKLEFS IYPAPQVSTA
       190        200        210        220        230        240
VVEPYNSILT THTTLEHSDC AFMVDNEAIY DICRRNLDIE RPTYTNLNRL ISQIVSSITA
       250        260        270        280        290        300
SLRFDGALNV DLTEFQTNLV PYPRIHFPLA TYAPVISAEK AYHEQLTVAE ITNACFEPAN
       310        320        330        340        350        360
QMVKCDPRHG KYMACCLLYR GDVVPKDVNA AIATIKTKRT IQFVDWCPTG FKVGINYQPP
       370        380        390        400        410        420
TVVPGGDLAK VQRAVCMLSN TTAIAEAWAR LDHKFDLMYA KRAFVHWYVG EGMEEGEFSE
       430        440
AREDMAALEK DYEEVGADSA EGDDEGEEY

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

11 N-termini - 10 C-termini - 10 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P68373-1-unknown	MRECIS...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P68373-40-unknown	KTIGGG...	40	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33780
P68373-68-unknown	VDLEPT...	68	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30314
P68373-70-unknown	LEPTVI...	70	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC32388
P68373-70-unknown	LEPTVI...	70		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P68373-92-unknown	LITGKE...	92	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30315
P68373-93-unknown	ITGKED...	93	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30316
P68373-93-unknown	ITGKED...	93	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29065
P68373-203-unknown	MVDNEA...	203	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33781
P68373-252-unknown	LTEFQT...	252	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC32389
P68373-254-unknown	EFQTNL...	254		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P68373-351-unknown	FKVGIN...	351	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33782
P68373-408-unknown	YVGEGM...	408	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33783

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QMPSDK	39	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33780
...PRAVFV	67	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30314
...AVFVDL	69	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32388
...FHPEQL	91	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30315
...HPEQLI	92	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30316
...HPEQLI	92	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29065
...SDCAFM	202	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33781
...ALNVDL	251	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32389
...WCPTGF	350	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33782
...AFVHWY	407	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33783
...EGEEY	449	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	39	PSDK.\|.KTIG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	67	AVFV.\|.VDLE	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TBA1C_MOUSE @67
GRAB_MOUSE	69	FVDL.\|.LEPT	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
CATE_MOUSE	91	PEQL.\|.LITG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TBA1C_MOUSE @91
CATE_MOUSE	92	EQLI.\|.ITGK	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> TBA1C_MOUSE @92
CATD_MOUSE	92	EQLI.\|.ITGK	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,
MMP2_MOUSE	202	CAFM.\|.MVDN	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
GRAB_MOUSE	251	NVDL.\|.LTEF	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
MMP2_MOUSE	350	PTGF.\|.FKVG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	407	VHWY.\|.YVGE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)