P70333: Heterogeneous nuclear ribonucleoprotein H2

General Information

Protein names	- Heterogeneous nuclear ribonucleoprotein H2 - hnRNP H2 - Heterogeneous nuclear ribonucleoprotein H' - hnRNP H' - Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed
Gene names	Hnrnph2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P70333

7 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MMLSTEGREG FVVKVRGLPW SCSAEEVMRF FSDCKIQNGT SGVRFIYTRE GRPSGEAFVE
        70         80         90        100        110        120
LESEDEVKLA LKKDRETMGH RYVEVFKSNS VEMDWVLKHT GPNSPDTAND GFVRLRGLPF
       130        140        150        160        170        180
GCSKEEIVQF FSGLEIVPNG MTLPVDFQGR STGEAFVQFA SQEIAEKALK KHKERIGHRY
       190        200        210        220        230        240
IEIFKSSRAE VRTHYDPPRK LMTMQRPGPY DRPGAGRGYN SIGRGAGFER MRRGAYGGGY
       250        260        270        280        290        300
GGYDDYGGYN DGYGFGSDRF GRDLNYCFSG MSDHRYGDGG SSFQSTTGHC VHMRGLPYRA
       310        320        330        340        350        360
TENDIYNFFS PLNPMRVHIE IGPDGRVTGE ADVEFATHED AVAAMAKDKA NMQHRYVELF
       370        380        390        400        410        420
LNSTAGTSGG AYDHSYVELF LNSTAGASGG AYGSQMMGGM GLSNQSSYGG PASQQLSGGY
       430        440
GGGYGGQSSM SGYDQVLQEN SSDYQSNLA

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P70333-1-Acetylation	MMLSTE...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P70333-2-Acetylation	MLSTEG...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P70333-2-Acetylation	MLSTEG...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P70333-95-unmodified	WVLKHT...	95			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P70333-95-unknown	WVLKHT...	95		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC32394
P70333-96-unknown	VLKHTG...	96		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33799
P70333-99-unmodified	HTGPNS...	99			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P70333-325-unknown	GRVTGE...	325		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC32395

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SVEMDW	94	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32394
...VEMDWV	95	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33799
...EIGPDG	324	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32395
...QSNLA	449	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_MOUSE	94	EMDW.\|.WVLK	inferred from experiment	unknown	MEROPS	Craik CS	Loeb CR et al.:Granzyme B proteolyzes receptor... (S01.136)	16798735,
MMP2_MOUSE	95	MDWV.\|.VLKH	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
GRAB_MOUSE	324	GPDG.\|.GRVT	inferred from experiment	unknown	MEROPS	Craik CS	Loeb CR et al.:Granzyme B proteolyzes receptor... (S01.136)	16798735,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)