Q3TKT4: Transcription activator BRG1

General Information

Protein names	- Transcription activator BRG1 - 3.6.4.- - ATP-dependent helicase SMARCA4 - BRG1-associated factor 190A - BAF190A - Protein brahma homolog 1 - SNF2-beta - SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
Gene names	Smarca4
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q3TKT4

2 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSTPDPPLGG TPRPGPSPGP GPSPGAMLGP SPGPSPGSAH SMMGPSPGPP SAGHPMPTQG
        70         80         90        100        110        120
PGGYPQDNMH QMHKPMESMH EKGMPDDPRY NQMKGMGMRS GAHTGMAPPP SPMDQHSQGY
       130        140        150        160        170        180
PSPLGGSEHA SSPVPASGPS SGPQMSSGPG GAPLDGSDPQ ALGQQNRGPT PFNQNQLHQL
       190        200        210        220        230        240
RAQIMAYKML ARGQPLPDHL QMAVQGKRPM PGMQQQMPTL PPPSVSATGP GPGPGPGPGP
       250        260        270        280        290        300
GPGPAPPNYS RPHGMGGPNM PPPGPSGVPP GMPGQPPGGP PKPWPEGPMA NAAAPTSTPQ
       310        320        330        340        350        360
KLIPPQPTGR PSPAPPAVPP AASPVMPPQT QSPGQPAQPA PLVPLHQKQS RITPIQKPRG
       370        380        390        400        410        420
LDPVEILQER EYRLQARIAH RIQELENLPG SLAGDLRTKA TIELKALRLL NFQRQLRQEV
       430        440        450        460        470        480
VVCMRRDTAL ETALNAKAYK RSKRQSLREA RITEKLEKQQ KIEQERKRRQ KHQEYLNSIL
       490        500        510        520        530        540
QHAKDFREYH RSVTGKLQKL TKAVATYHAN TEREQKKENE RIEKERMRRL MAEDEEGYRK
       550        560        570        580        590        600
LIDQKKDKRL AYLLQQTDEY VANLTELVRQ HKAAQVAKEK KKKKKKKKAE NAEGQTPAIG
       610        620        630        640        650        660
PDGEPLDETS QMSDLPVKVI HVESGKILTG TDAPKAGQLE AWLEMNPGYE VAPRSDSEES
       670        680        690        700        710        720
GSEEEEEEEE EEQPQPAQPP TLPVEEKKKI PDPDSDDVSE VDARHIIENA KQDVDDEYGV
       730        740        750        760        770        780
SQALARGLQS YYAVAHAVTE RVDKQSALMV NGVLKQYQIK GLEWLVSLYN NNLNGILADE
       790        800        810        820        830        840
MGLGKTIQTI ALITYLMEHK RINGPFLIIV PLSTLSNWAY EFDKWAPSVV KVSYKGSPAA
       850        860        870        880        890        900
RRAFVPQLRS GKFNVLLTTY EYIIKDKHIL AKIRWKYMIV DEGHRMKNHH CKLTQVLNTH
       910        920        930        940        950        960
YVAPRRLLLT GTPLQNKLPE LWALLNFLLP TIFKSCSTFE QWFNAPFAMT GEKVDLNEEE
       970        980        990       1000       1010       1020
TILIIRRLHK VLRPFLLRRL KKEVEAQLPE KVEYVIKCDM SALQRVLYRH MQAKGVLLTD
      1030       1040       1050       1060       1070       1080
GSEKDKKGKG GTKTLMNTIM QLRKICNHPY MFQHIEESFS EHLGFTGGIV QGLDLYRASG
      1090       1100       1110       1120       1130       1140
KFELLDRILP KLRATNHKVL LFCQMTSLMT IMEDYFAYRG FKYLRLDGTT KAEDRGMLLK
      1150       1160       1170       1180       1190       1200
TFNEPGSEYF IFLLSTRAGG LGLNLQSADT VIIFDSDWNP HQDLQAQDRA HRIGQQNEVR
      1210       1220       1230       1240       1250       1260
VLRLCTVNSV EEKILAAAKY KLNVDQKVIQ AGMFDQKSSS HERRAFLQAI LEHEEQDEEE
      1270       1280       1290       1300       1310       1320
DEVPDDETVN QMIARHEEEF DLFMRMDLDR RREEARNPKR KPRLMEEDEL PSWIIKDDAE
      1330       1340       1350       1360       1370       1380
VERLTCEEEE EKMFGRGSRH RKEVDYSDSL TEKQWLKAIE EGTLEEIEEE VRQKKSSRKR
      1390       1400       1410       1420       1430       1440
KRDSEAGSST PTTSTRSRDK DEESKKQKKR GRPPAEKLSP NPPNLTKKMK KIVDAVIKYK
      1450       1460       1470       1480       1490       1500
DSSGRQLSEV FIQLPSRKEL PEYYELIRKP VDFKKIKERI RNHKYRSLND LEKDVMLLCQ
      1510       1520       1530       1540       1550       1560
NAQTFNLEGS LIYEDSIVLQ SVFTSVRQKI EKEDDSEGEE SEEEEEGEEE GSESESRSVK
      1570       1580       1590       1600       1610
VKIKLGRKEK AQDRLKGGRR RPSRGSRAKP VVSDDDSEEE QEEDRSGSGS EED

Isoforms

- Isoform 2 of Transcription activator BRG1

Sequence View

        10         20         30         40         50         60
MSTPDPPLGG TPRPGPSPGP GPSPGAMLGP SPGPSPGSAH SMMGPSPGPP SAGHPMPTQG
        70         80         90        100        110        120
PGGYPQDNMH QMHKPMESMH EKGMPDDPRY NQMKGMGMRS GAHTGMAPPP SPMDQHSQGY
       130        140        150        160        170        180
PSPLGGSEHA SSPVPASGPS SGPQMSSGPG GAPLDGSDPQ ALGQQNRGPT PFNQNQLHQL
       190        200        210        220        230        240
RAQIMAYKML ARGQPLPDHL QMAVQGKRPM PGMQQQMPTL PPPSVSATGP GPGPGPGPGP
       250        260        270        280        290        300
GPGPAPPNYS RPHGMGGPNM PPPGPSGVPP GMPGQPPGGP PKPWPEGPMA NAAAPTSTPQ
       310        320        330        340        350        360
KLIPPQPTGR PSPAPPAVPP AASPVMPPQT QSPGQPAQPA PLVPLHQKQS RITPIQKPRG
       370        380        390        400        410        420
LDPVEILQER EYRLQARIAH RIQELENLPG SLAGDLRTKA TIELKALRLL NFQRQLRQEV
       430        440        450        460        470        480
VVCMRRDTAL ETALNAKAYK RSKRQSLREA RITEKLEKQQ KIEQERKRRQ KHQEYLNSIL
       490        500        510        520        530        540
QHAKDFREYH RSVTGKLQKL TKAVATYHAN TEREQKKENE RIEKERMRRL MAEDEEGYRK
       550        560        570        580        590        600
LIDQKKDKRL AYLLQQTDEY VANLTELVRQ HKAAQVAKEK KKKKKKKKAE NAEGQTPAIG
       610        620        630        640        650        660
PDGEPLDETS QMSDLPVKVI HVESGKILTG TDAPKAGQLE AWLEMNPGYE VAPRSDSEES
       670        680        690        700        710        720
GSEEEEEEEE EEQPQPAQPP TLPVEEKKKI PDPDSDDVSE VDARHIIENA KQDVDDEYGV
       730        740        750        760        770        780
SQALARGLQS YYAVAHAVTE RVDKQSALMV NGVLKQYQIK GLEWLVSLYN NNLNGILADE
       790        800        810        820        830        840
MGLGKTIQTI ALITYLMEHK RINGPFLIIV PLSTLSNWAY EFDKWAPSVV KVSYKGSPAA
       850        860        870        880        890        900
RRAFVPQLRS GKFNVLLTTY EYIIKDKHIL AKIRWKYMIV DEGHRMKNHH CKLTQVLNTH
       910        920        930        940        950        960
YVAPRRLLLT GTPLQNKLPE LWALLNFLLP TIFKSCSTFE QWFNAPFAMT GEKVDLNEEE
       970        980        990       1000       1010       1020
TILIIRRLHK VLRPFLLRRL KKEVEAQLPE KVEYVIKCDM SALQRVLYRH MQAKGVLLTD
      1030       1040       1050       1060       1070       1080
GSEKDKKGKG GTKTLMNTIM QLRKICNHPY MFQHIEESFS EHLGFTGGIV QGLDLYRASG
      1090       1100       1110       1120       1130       1140
KFELLDRILP KLRATNHKVL LFCQMTSLMT IMEDYFAYRG FKYLRLDGTT KAEDRGMLLK
      1150       1160       1170       1180       1190       1200
TFNEPGSEYF IFLLSTRAGG LGLNLQSADT VIIFDSDWNP HQDLQAQDRA HRIGQQNEVR
      1210       1220       1230       1240       1250       1260
VLRLCTVNSV EEKILAAAKY KLNVDQKVIQ AGMFDQKSSS HERRAFLQAI LEHEEQDEEE
      1270       1280       1290       1300       1310       1320
DEVPDDETVN QMIARHEEEF DLFMRMDLDR RREEARNPKR KPRLMEEDEL PSWIIKDDAE
      1330       1340       1350       1360       1370       1380
VERLTCEEEE EKMFGRGSRH RKEVDYSDSL TEKQWLKAIE EGTLEEIEEE VRQKKSSRKR
      1390       1400       1410       1420       1430       1440
KRDSEAGSST PTTSTRSRDK DEESKKQKKR GRPPAEKLSP NPPNLTKKMK KIVDAVIKYK
      1450       1460       1470       1480       1490       1500
DSSGRQLSEV FIQLPSRKEL PEYYELIRKP VDFKKIKERI RNHKYRSLND LEKDVMLLCQ
      1510       1520       1530       1540       1550       1560
NAQTFNLEGS LIYEDSIVLQ SVFTSVRQKI EKEDDSEGEE SEEEEEGEEE GSESESRSVK
      1570       1580       1590       1600       1610
VKIKLGRKEK AQDRLKGGRR RPSRGSRAKP VVSDDDSEEE QEEDRSGSGS EED

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q3TKT4-1-unknown	MSTPDP...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q3TKT4-1-unknown	MSTPDP...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt90016
Q3TKT4-695-unknown	SDDVSE...	695	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32429
Q3TKT4-695-unknown	SDDVSE...	695	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt155821

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...IPDPDS	694	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32429
...IPDPDS	694	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt139273
...PPNLTK	1426	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000133535
...GSEED	1613	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GSEED	1613	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt85634

TopFIND

Q3TKT4: Transcription activator BRG1

General Information

2

N-termini

3

C-termini

1

Cleavages

0

Substrates

Sequence

Isoforms

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Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates