Q6A068: Cell division cycle 5-like protein

General Information

Protein names	- Cell division cycle 5-like protein - Cdc5-like protein
Gene names	Cdc5l
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6A068

7 N-termini

5 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPRIMIKGGV WRNTEDEILK AAVMKYGKNQ WSRIASLLHR KSAKQCKARW YEWLDPSIKK
        70         80         90        100        110        120
TEWSREEEEK LLHLAKLMPT QWRTIAPIIG RTAAQCLEHY EFLLDKTAQR DNEEETTDDP
       130        140        150        160        170        180
RKLKPGEIDP NPETKPARPD PIDMDEDELE MLSEARARLA NTQGKKAKRK AREKQLEEAR
       190        200        210        220        230        240
RLAALQKRRE LRAAGIEIQK KRKKKRGVDY NAEIPFEKKP ALGFYDTSEE NYQALDADFR
       250        260        270        280        290        300
KLRQQDLDGE LRSEKEGRDR KKDKQHLKRK KESDLPSAIL QTSGVSEFTK KRSKLVLPAP
       310        320        330        340        350        360
QISDAELQEV VKVGQASEVA RQTAEESGIT NSASSTLLSE YNVTNNSIAL RTPRTPASQD
       370        380        390        400        410        420
RILQEAQNLM ALTNVDTPLK GGLNTPLHES DFSGVTPQRQ VVQTPNTVLS TPFRTPSNGA
       430        440        450        460        470        480
EGLTPRSGTT PKPVTNATPG RTPLRDKLNI NPEDGMADYS DPSYVKQMER ESREHLRLGL
       490        500        510        520        530        540
LGLPAPKNDF EIVLPENAEK ELEEREIDDT YIEDAADVDA RKQAIRDAER VKEMKRMHKA
       550        560        570        580        590        600
VQKDLPRPSE VNETILRPLN VEPPLTDLQK SEELIKKEMI TMLHYDLLHH PYEPSGNKKG
       610        620        630        640        650        660
KNVGFATNNS EHITYLEHSP YEKFSKEDLK KAQDALVQEM EVVKQGMSHG ELSSEAYNQV
       670        680        690        700        710        720
WEECYSQVLY LPAQSRYTRA NLASKKDRIE SLEKRLEINR GHMTTEAKRA AKMEKKMKIL
       730        740        750        760        770        780
LGGYQSRAMG LMKQLNDLWD QIEQAHLELR TFEELKKHED SAIPRRLECL KEDVQRQQER
       790        800
EKELQQRYAD LLMEKETLQA KF

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

7 N-termini - 5 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q6A068-1-unknown	MPRIMI...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q6A068-137-unmodified	ARPDPI...	137		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q6A068-146-unknown	EDELEM...	146	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC32466
Q6A068-226-unknown	DTSEEN...	226	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC32618
Q6A068-310-unknown	VVKVGQ...	310	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30593
Q6A068-482-unmodified	GLPAPK...	482		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
Q6A068-512-unknown	IEDAAD...	512	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30594

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PIDMDE	145	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32466
...ALGFYD	225	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32618
...AELQEV	309	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30593
...IDDTYI	511	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30594
...LQAKF	802	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_MOUSE	145	DMDE.\|.EDEL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAC_MOUSE	225	GFYD.\|.DTSE	inferred from experiment	unknown	MEROPS	Bird PI	Kaiserman D et al.:Structure of granzyme C reveals... (S01.137)	19299505,
CATE_MOUSE	309	LQEV.\|.VVKV	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> CDC5L_MOUSE @309
CATE_MOUSE	511	DTYI.\|.IEDA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> CDC5L_MOUSE @511

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)