Q9Z315: U4/U6.U5 tri-snRNP-associated protein 1

General Information

Protein names	- U4/U6.U5 tri-snRNP-associated protein 1 - Hypoxia-associated factor - Squamous cell carcinoma antigen recognized by T-cells 1 - SART-1 - mSART-1
Gene names	Sart1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Z315

7 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGSSKKHRGE KEAAGTTAAA GTGGTTEQPP RHREHKKHKH RSSGGGSSGG ERRKRSRERG
        70         80         90        100        110        120
SERGSGRRGA EAEARSGAHG RERSQAEPSE RRVKREKRDD GYEAAASSKA SSGDASSLSI
       130        140        150        160        170        180
EETNKLRAKL GLKPLEVNAV KKEAGTKEEP VAADVINPMA LRQREELREK LAAAKEKRLL
       190        200        210        220        230        240
NQKLGKIKTL GEDDPWLDDT AAWIERSRQL QKEKDLAEKR AKLLEEMDQE FGVSTLVEEE
       250        260        270        280        290        300
FEQRRQDLYS ARDLQGLTVE HAIDSFREGE TVVLTLKDKG VLQDGEDVLV NVNMVDKERA
       310        320        330        340        350        360
DKNVELRKKK PDYLPYAEDE SVDDLAQQKP RSILAKYDEE LEGERPHSFR LEQGGMADGL
       370        380        390        400        410        420
RERELEEIRT KLRLQAQSLS SVGPRLASEY LSPEEMVTFK KTKRRVKKIR KKEKEVIMRA
       430        440        450        460        470        480
DDLLPLGDQT QDGDFGSRLR GRGRRRVPEV EEEALEDEEK DPVAQPPPSD DTRVENMDIS
       490        500        510        520        530        540
DEEDGGALPP GSPEGLEEDE AELELQKQLE KGRRLRQLQQ LQQLRDSGEK VLEIVKKLES
       550        560        570        580        590        600
RQRGWEEEED PERKGTIVFN ATSEFCRTLG EIPTYGLAGN REEQEELMDF ERDEERSANG
       610        620        630        640        650        660
GSESDGEENI GWSTVNLDEE KQHQDFSASS TTILDEEPIV NRGLAAALLL CQNKGLLETT
       670        680        690        700        710        720
VQKVARVKAP NKSLPSAVYC IEDKMAIDDK YSRREEYRGF TQDFKEKDGY KPDVKIEYVD
       730        740        750        760        770        780
ETGRKLTPKE AFRQLSHRFH GKGSGKMKTE RRMKKLDEEA LLKKMSSSDT PLGTVALLQE
       790        800
KQKAQKTPYI VLSGSGKSMN ANTITK

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9Z315-1-unknown	MGSSKK...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Z315-8-unknown	RGEKEA...	8	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q9Z315-236-unknown	LVEEEF...	236	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34416
Q9Z315-254-unknown	LQGLTV...	254	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34417
Q9Z315-267-unknown	REGETV...	267	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q9Z315-279-unknown	KGVLQD...	279	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC32604
Q9Z315-571-unmodified	EIPTYG...	571		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FGVSTL	235	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34416
...YSARDL	253	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC34417
...LTLKDK	278	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32604
...NTITK	806	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_MOUSE	235	VSTL.\|.LVEE	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
MMP2_MOUSE	253	ARDL.\|.LQGL	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
GRAB_MOUSE	278	LKDK.\|.KGVL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)