P62631: Elongation factor 1-alpha 2

General Information

Protein names	- Elongation factor 1-alpha 2 - EF-1-alpha-2 - Eukaryotic elongation factor 1 A-2 - eEF1A-2 - Statin-S1
Gene names	Eef1a2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P62631

8 N-termini

5 C-termini

7 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGKEKTHINI VVIGHVDSGK STTTGHLIYK CGGIDKRTIE KFEKEAAEMG KGSFKYAWVL
        70         80         90        100        110        120
DKLKAERERG ITIDISLWKF ETTKYYITII DAPGHRDFIK NMITGTSQAD CAVLIVAAGV
       130        140        150        160        170        180
GEFEAGISKN GQTREHALLA YTLGVKQLIV GVNKMDSTEP AYSEKRYDEI VKEVSAYIKK
       190        200        210        220        230        240
IGYNPATVPF VPISGWHGDN MLEPSPNMPW FKGWKVERKE GNASGVSLLE ALDTILPPTR
       250        260        270        280        290        300
PTDKPLRLPL QDVYKIGGIG TVPVGRVETG ILRPGMVVTF APVNITTEVK SVEMHHEALS
       310        320        330        340        350        360
EALPGDNVGF NVKNVSVKDI RRGNVCGDSK ADPPQEAAQF TSQVIILNHP GQISAGYSPV
       370        380        390        400        410        420
IDCHTAHIAC KFAELKEKID RRSGKKLEDN PKSLKSGDAA IVEMVPGKPM CVESFSQYPP
       430        440        450        460
LGRFAVRDMR QTVAVGVIKN VEKKSGGAGK VTKSAQKAQK AGK

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

8 N-termini - 5 C-termini - 7 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P62631-1-unknown	MGKEKT...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P62631-59-unknown	VLDKLK...	59	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28984
P62631-59-unknown	VLDKLK...	59	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30179
P62631-102-unmodified	MITGTS...	102		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P62631-115-unknown	IVAAGV...	115	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28985
P62631-115-unknown	IVAAGV...	115	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30180
P62631-253-unknown	VYKIGG...	253	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC32365
P62631-255-unknown	KIGGIG...	255	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28986
P62631-255-unknown	KIGGIG...	255	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC30181
P62631-256-unmodified	IGGIGT...	256		N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P62631-257-unmodified	GGIGTV...	257		unknown			Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from...	20208520

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...FKYAWV	58	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28984
...FKYAWV	58	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30179
...DCAVLI	114	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28985
...DCAVLI	114	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30180
...LPLQDV	252	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32365
...LQDVYK	254	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28986
...LQDVYK	254	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30181
...QKAGK	463	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATD_MOUSE	58	YAWV.\|.VLDK	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,
CATE_MOUSE	58	YAWV.\|.VLDK	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> EF1A2_MOUSE @58
CATD_MOUSE	114	AVLI.\|.IVAA	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,
CATE_MOUSE	114	AVLI.\|.IVAA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> EF1A2_MOUSE @114
GRAB_MOUSE	252	LQDV.\|.VYKI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
CATD_MOUSE	254	DVYK.\|.KIGG	inferred from experiment	unknown	MEROPS	Zornig M	Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009)	22388353,
CATE_MOUSE	254	DVYK.\|.KIGG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> EF1A2_MOUSE @254

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)