P17182: Alpha-enolase

General Information

Protein names	- Alpha-enolase - 4.2.1.11 - 2-phospho-D-glycerate hydro-lyase - Enolase 1 - Non-neural enolase - NNE
Gene names	Eno1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P17182

32 N-termini

29 C-termini

40 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSILRIHARE IFDSRGNPTV EVDLYTAKGL FRAAVPSGAS TGIYEALELR DNDKTRFMGK
        70         80         90        100        110        120
GVSQAVEHIN KTIAPALVSK KVNVVEQEKI DKLMIEMDGT ENKSKFGANA ILGVSLAVCK
       130        140        150        160        170        180
AGAVEKGVPL YRHIADLAGN PEVILPVPAF NVINGGSHAG NKLAMQEFMI LPVGASSFRE
       190        200        210        220        230        240
AMRIGAEVYH NLKNVIKEKY GKDATNVGDE GGFAPNILEN KEALELLKTA IAKAGYTDQV
       250        260        270        280        290        300
VIGMDVAASE FYRSGKYDLD FKSPDDPSRY ITPDQLADLY KSFVQNYPVV SIEDPFDQDD
       310        320        330        340        350        360
WGAWQKFTAS AGIQVVGDDL TVTNPKRIAK AASEKSCNCL LLKVNQIGSV TESLQACKLA
       370        380        390        400        410        420
QSNGWGVMVS HRSGETEDTF IADLVVGLCT GQIKTGAPCR SERLAKYNQI LRIEEELGSK
       430
AKFAGRSFRN PLAK

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

32 N-termini - 29 C-termini - 40 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P17182-2-unknown	MSILRI...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P17182-2-unknown	MSILRI...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P17182-2-Acetylation	SILRIH...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P17182-2-Acetylation	SILRIH...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P17182-22-unknown	VDLYTA...	22		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29756
P17182-24-unknown	LYTAKG...	24		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29757
P17182-24-unknown	LYTAKG...	24		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC32319
P17182-24-unknown	LYTAKG...	24		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28779
P17182-25-unknown	YTAKGL...	25		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29758
P17182-25-unknown	YTAKGL...	25		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28780
P17182-43-unknown	IYEALE...	43		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29759
P17182-111-unknown	ILGVSL...	111		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33396
P17182-114-unknown	VSLAVC...	114		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29760
P17182-116-unknown	LAVCKA...	116		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28781
P17182-117-unknown	AVCKAG...	117		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29761
P17182-117-unknown	AVCKAG...	117		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28782
P17182-118-unknown	VCKAGA...	118		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29762
P17182-120-unmodified	KAGAVE...	120			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P17182-168-unknown	FMILPV...	168		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29763
P17182-168-unknown	FMILPV...	168		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P17182-168-unknown	FMILPV...	168		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P17182-169-unknown	MILPVG...	169		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29764
P17182-169-unknown	MILPVG...	169		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28783
P17182-172-unknown	PVGASS...	172		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29765
P17182-240-unknown	VVIGMD...	240		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29766
P17182-244-unknown	MDVAAS...	244		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29767
P17182-244-unknown	MDVAAS...	244		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28784
P17182-245-unknown	DVAASE...	245		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28785
P17182-254-acetylation	SGKYDL...	254	acetylation-		N-TAILS		Overall CM.	auf dem Keller U.: A statistics-based platform for quantitative N-terminome...	20305283
P17182-254-unmodified	SGKYDL...	254			N-TAILS		Overall CM.	Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies...	20208520
P17182-308-unknown	TASAGI...	308		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28786
P17182-310-unmodified	SAGIQV...	310			N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P17182-313-unknown	IQVVGD...	313		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29768
P17182-313-unknown	IQVVGD...	313		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28787
P17182-313-unknown	IQVVGD...	313		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33397
P17182-320-unknown	LTVTNP...	320		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29769
P17182-381-unknown	IADLVV...	381		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29770
P17182-384-unknown	LVVGLC...	384		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29771
P17182-384-unknown	LVVGLC...	384		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28788
P17182-384-unknown	LVVGLC...	384		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33398
P17182-385-unknown	VVGLCT...	385		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29772
P17182-385-unknown	VVGLCT...	385		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28789
P17182-388-unknown	LCTGQI...	388		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28790
P17182-388-unknown	LCTGQI...	388		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33399
P17182-389-unknown	CTGQIK...	389		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29773
P17182-389-unknown	CTGQIK...	389		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28791
P17182-389-unknown	CTGQIK...	389		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC33400
P17182-413-acetylation	IEEELG...	413	acetylation-		N-TAILS		Overall CM.	Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9...	20305284
P17182-415-unknown	EELGSK...	415		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29774
P17182-415-unknown	EELGSK...	415		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC28792
P17182-418-unknown	GSKAKF...	418		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC29775

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...NPTVEV	21	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29756
...TVEVDL	23	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29757
...TVEVDL	23	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC32319
...TVEVDL	23	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28779
...VEVDLY	24	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29758
...VEVDLY	24	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28780
...GASTGI	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29759
...SQAVEH	67	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000120059
...FGANAI	110	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33396
...NAILGV	113	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29760
...ILGVSL	115	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28781
...LGVSLA	116	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29761
...LGVSLA	116	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28782
...GVSLAV	117	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29762
...SLAVCK	119	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123695
...LAMQEF	167	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29763
...AMQEFM	168	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29764
...AMQEFM	168	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28783
...EFMILP	171	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29765
...ILENKE	221	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000114361
...GYTDQV	239	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29766
...QVVIGM	243	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29767
...QVVIGM	243	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28784
...VVIGMD	244	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28785
...AWQKFT	307	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28786
...TASAGI	312	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29768
...TASAGI	312	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28787
...TASAGI	312	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33397
...VVGDDL	319	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29769
...TEDTFI	380	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29770
...TFIADL	383	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29771
...TFIADL	383	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28788
...TFIADL	383	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33398
...FIADLV	384	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29772
...FIADLV	384	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28789
...DLVVGL	387	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28790
...DLVVGL	387	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33399
...LVVGLC	388	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29773
...LVVGLC	388	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28791
...LVVGLC	388	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC33400
...ILRIEE	414	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29774
...ILRIEE	414	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC28792
...IEEELG	417	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC29775
...NPLAK	434	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATE_MOUSE	21	TVEV.\|.VDLY	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ENOA_MOUSE @21
CATE_MOUSE	23	EVDL.\|.LYTA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ENOA_MOUSE @23
GRAB_MOUSE	23	EVDL.\|.LYTA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
CATD_MOUSE	23	EVDL.\|.LYTA	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ENOA_MOUSE @23
CATE_MOUSE	24	VDLY.\|.YTAK	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ENOA_MOUSE @24
CATD_MOUSE	24	VDLY.\|.YTAK	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ENOA_MOUSE @24
CATE_MOUSE	42	STGI.\|.IYEA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ENOA_MOUSE @42
MMP2_MOUSE	110	ANAI.\|.ILGV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	113	ILGV.\|.VSLA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ENOA_MOUSE @113
CATD_MOUSE	115	GVSL.\|.LAVC	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ENOA_MOUSE @115
CATE_MOUSE	116	VSLA.\|.AVCK	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ENOA_MOUSE @116
CATD_MOUSE	116	VSLA.\|.AVCK	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ENOA_MOUSE @116
CATE_MOUSE	117	SLAV.\|.VCKA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ENOA_MOUSE @117
CATE_MOUSE	167	MQEF.\|.FMIL	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ENOA_MOUSE @167
CATE_MOUSE	168	QEFM.\|.MILP	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ENOA_MOUSE @168
CATD_MOUSE	168	QEFM.\|.MILP	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ENOA_MOUSE @168
CATE_MOUSE	171	MILP.\|.PVGA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ENOA_MOUSE @171
CATE_MOUSE	239	TDQV.\|.VVIG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ENOA_MOUSE @239
CATE_MOUSE	243	VIGM.\|.MDVA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ENOA_MOUSE @243
CATD_MOUSE	243	VIGM.\|.MDVA	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ENOA_MOUSE @243
CATD_MOUSE	244	IGMD.\|.DVAA	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ENOA_MOUSE @244
CATD_MOUSE	307	QKFT.\|.TASA	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ENOA_MOUSE @307
CATE_MOUSE	312	SAGI.\|.IQVV	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ENOA_MOUSE @312
CATD_MOUSE	312	SAGI.\|.IQVV	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ENOA_MOUSE @312
MMP2_MOUSE	312	SAGI.\|.IQVV	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	319	GDDL.\|.LTVT	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ENOA_MOUSE @319
CATE_MOUSE	380	DTFI.\|.IADL	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ENOA_MOUSE @380
CATE_MOUSE	383	IADL.\|.LVVG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ENOA_MOUSE @383
CATD_MOUSE	383	IADL.\|.LVVG	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ENOA_MOUSE @383
MMP2_MOUSE	383	IADL.\|.LVVG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	384	ADLV.\|.VVGL	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ENOA_MOUSE @384
CATD_MOUSE	384	ADLV.\|.VVGL	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ENOA_MOUSE @384
CATD_MOUSE	387	VVGL.\|.LCTG	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ENOA_MOUSE @387
MMP2_MOUSE	387	VVGL.\|.LCTG	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	388	VGLC.\|.CTGQ	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ENOA_MOUSE @388
CATD_MOUSE	388	VGLC.\|.CTGQ	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ENOA_MOUSE @388
MMP2_MOUSE	388	VGLC.\|.CTGQ	inferred from experiment	unknown	MEROPS	Overall CM	auf dem Keller U et al.:A statistics-based platform for... (M10.003)	20305283,
CATE_MOUSE	414	RIEE.\|.EELG	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ENOA_MOUSE @414
CATD_MOUSE	414	RIEE.\|.EELG	inferred from experiment	unknown	MEROPS		Merops CATD_MOUSE -> ENOA_MOUSE @414
CATE_MOUSE	417	EELG.\|.GSKA	inferred from experiment	unknown	MEROPS		Merops CATE_MOUSE -> ENOA_MOUSE @417

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)