A8CG34: Nuclear envelope pore membrane protein POM 121C
Protein names | - Nuclear envelope pore membrane protein POM 121C - Nuclear pore membrane protein 121-2 - POM121-2 - Pore membrane protein of 121 kDa C |
---|---|
Gene names | POM121C |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | A8CG34 |
3
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSPAAAAAGA GERRRPIASV RDGRGRGCGG PAGAALLGLS LVGLLLYLVP AAAALAWLAV
70 80 90 100 110 120
GTTAAWWGLS REPRGSRPLS SFVQKARHRR TLFASPPAKS TANGNLLEPR TLLEGPDPAE
130 140 150 160 170 180
LLLMGSYLGK PGPPQPAPAP EGQDLRNRPG RRPPARPAPR STPPSQPTHR VHHFYPSLPT
190 200 210 220 230 240
PLLRPSGRPS PRDRGTLPDR FVITPRRRYP IHQTQYSCPG VLPTVCWNGY HKKAVLSPRN
250 260 270 280 290 300
SRMVCSPVTV RIAPPDRRFS RSAIPEQIIS STLSSPSSNA PDPCAKETVL SALKEKKKKR
310 320 330 340 350 360
TVEEEDQIFL DGQENKRRRH DSSGSGHSAF EPLVASGVPA SFVPKPGSLK RGLNSQSSDD
370 380 390 400 410 420
HLNKRSRSSS MSSLTGAYTS GIPSSSRNAI TSSYSSTRGI SQLWKRNGPS SSPFSSPASS
430 440 450 460 470 480
RSQTPERPAK KIREEELCHH SSSSTPLAAD KESQGEKAAD TTPRKKQNSN SQSTPGSSGQ
490 500 510 520 530 540
RKRKVQLLPS RRGEQLTLPP PPQLGYSITA EDLDLEKKAS LQWFNQALED KSDAASNSVT
550 560 570 580 590 600
ETPPTTQPSF TFTLPAAATA SPPTSLLAPS TNPLLESLKK MQTPPSLPPC PESAGAATTE
610 620 630 640 650 660
ALSPPKTPSL LPPLGLSQSG PPGLLPSPSF DSKPPTTLLG LIPAPSMVPA TDTKAPPTLQ
670 680 690 700 710 720
AETATKPQAT SAPSPAPKQS FLFGTQNTSP SSPAAPAASS ASPMFKPIFT APPKSEKEGL
730 740 750 760 770 780
TPPGPSVSAT APSSSSLPTT TSTTAPTFQP VFSSMGPPAS VPLPAPFFKQ TTTPATAPTT
790 800 810 820 830 840
TAPLFTGLAS ATSAVAPITS ASPSTDSASK PAFGFGINSV SSSSVSTTTS TATAASQPFL
850 860 870 880 890 900
FGAPQASAAS FTPAMGSIFQ FGKPPALPTT TTVTTFSQSL PTAVPTATSS SAADFSGFGS
910 920 930 940 950 960
TLATSAPATS SQPTLTFSNT STPTFNIPFG SSAKSPLPSY PGANPQPAFG AAEGQPPGAA
970 980 990 1000 1010 1020
KPALTPSFGS SFTFGNSAAP APATAPTPAP ASTIKIVPAH VPTPIQPTFG GATHSAFGLK
1030 1040 1050 1060 1070 1080
ATASAFGAPA SSQPAFGGST AVFSFGAATS SGFGATTQTA SSGSSSSVFG STTPSPFTFG
1090 1100 1110 1120 1130 1140
GSAAPAGSGS FGINVATPGS SATTGAFSFG AGQSGSTATS TPFTGGLGQN ALGTTGQSTP
1150 1160 1170 1180 1190 1200
FAFNVGSTTE SKPVFGGTAT PTFGQNTPAP GVGTSGSSLS FGASSAPAQG FVGVGPFGSA
1210 1220
APSFSIGAGS KTPGARQRLQ ARRQHTRKK
Isoforms
- Isoform 2 of Nuclear envelope pore membrane protein POM 121C - Isoform 2 of Nuclear envelope pore membrane protein POM 121CSequence View
10 20 30 40 50 60
MSPAAAAAGA GERRRPIASV RDGRGRGCGG PAGAALLGLS LVGLLLYLVP AAAALAWLAV
70 80 90 100 110 120
GTTAAWWGLS REPRGSRPLS SFVQKARHRR TLFASPPAKS TANGNLLEPR TLLEGPDPAE
130 140 150 160 170 180
LLLMGSYLGK PGPPQPAPAP EGQDLRNRPG RRPPARPAPR STPPSQPTHR VHHFYPSLPT
190 200 210 220 230 240
PLLRPSGRPS PRDRGTLPDR FVITPRRRYP IHQTQYSCPG VLPTVCWNGY HKKAVLSPRN
250 260 270 280 290 300
SRMVCSPVTV RIAPPDRRFS RSAIPEQIIS STLSSPSSNA PDPCAKETVL SALKEKKKKR
310 320 330 340 350 360
TVEEEDQIFL DGQENKRRRH DSSGSGHSAF EPLVASGVPA SFVPKPGSLK RGLNSQSSDD
370 380 390 400 410 420
HLNKRSRSSS MSSLTGAYTS GIPSSSRNAI TSSYSSTRGI SQLWKRNGPS SSPFSSPASS
430 440 450 460 470 480
RSQTPERPAK KIREEELCHH SSSSTPLAAD KESQGEKAAD TTPRKKQNSN SQSTPGSSGQ
490 500 510 520 530 540
RKRKVQLLPS RRGEQLTLPP PPQLGYSITA EDLDLEKKAS LQWFNQALED KSDAASNSVT
550 560 570 580 590 600
ETPPTTQPSF TFTLPAAATA SPPTSLLAPS TNPLLESLKK MQTPPSLPPC PESAGAATTE
610 620 630 640 650 660
ALSPPKTPSL LPPLGLSQSG PPGLLPSPSF DSKPPTTLLG LIPAPSMVPA TDTKAPPTLQ
670 680 690 700 710 720
AETATKPQAT SAPSPAPKQS FLFGTQNTSP SSPAAPAASS ASPMFKPIFT APPKSEKEGL
730 740 750 760 770 780
TPPGPSVSAT APSSSSLPTT TSTTAPTFQP VFSSMGPPAS VPLPAPFFKQ TTTPATAPTT
790 800 810 820 830 840
TAPLFTGLAS ATSAVAPITS ASPSTDSASK PAFGFGINSV SSSSVSTTTS TATAASQPFL
850 860 870 880 890 900
FGAPQASAAS FTPAMGSIFQ FGKPPALPTT TTVTTFSQSL PTAVPTATSS SAADFSGFGS
910 920 930 940 950 960
TLATSAPATS SQPTLTFSNT STPTFNIPFG SSAKSPLPSY PGANPQPAFG AAEGQPPGAA
970 980 990 1000 1010 1020
KPALTPSFGS SFTFGNSAAP APATAPTPAP ASTIKIVPAH VPTPIQPTFG GATHSAFGLK
1030 1040 1050 1060 1070 1080
ATASAFGAPA SSQPAFGGST AVFSFGAATS SGFGATTQTA SSGSSSSVFG STTPSPFTFG
1090 1100 1110 1120 1130 1140
GSAAPAGSGS FGINVATPGS SATTGAFSFG AGQSGSTATS TPFTGGLGQN ALGTTGQSTP
1150 1160 1170 1180 1190 1200
FAFNVGSTTE SKPVFGGTAT PTFGQNTPAP GVGTSGSSLS FGASSAPAQG FVGVGPFGSA
1210 1220
APSFSIGAGS KTPGARQRLQ ARRQHTRKK
10 20 30 40 50 60
MSPAAAAAGA GERRRPIASV RDGRGRGCGG PAGAALLGLS LVGLLLYLVP AAAALAWLAV
70 80 90 100 110 120
GTTAAWWGLS REPRGSRPLS SFVQKARHRR TLFASPPAKS TANGNLLEPR TLLEGPDPAE
130 140 150 160 170 180
LLLMGSYLGK PGPPQPAPAP EGQDLRNRPG RRPPARPAPR STPPSQPTHR VHHFYPSLPT
190 200 210 220 230 240
PLLRPSGRPS PRDRGTLPDR FVITPRRRYP IHQTQYSCPG VLPTVCWNGY HKKAVLSPRN
250 260 270 280 290 300
SRMVCSPVTV RIAPPDRRFS RSAIPEQIIS STLSSPSSNA PDPCAKETVL SALKEKKKKR
310 320 330 340 350 360
TVEEEDQIFL DGQENKRRRH DSSGSGHSAF EPLVASGVPA SFVPKPGSLK RGLNSQSSDD
370 380 390 400 410 420
HLNKRSRSSS MSSLTGAYTS GIPSSSRNAI TSSYSSTRGI SQLWKRNGPS SSPFSSPASS
430 440 450 460 470 480
RSQTPERPAK KIREEELCHH SSSSTPLAAD KESQGEKAAD TTPRKKQNSN SQSTPGSSGQ
490 500 510 520 530 540
RKRKVQLLPS RRGEQLTLPP PPQLGYSITA EDLDLEKKAS LQWFNQALED KSDAASNSVT
550 560 570 580 590 600
ETPPTTQPSF TFTLPAAATA SPPTSLLAPS TNPLLESLKK MQTPPSLPPC PESAGAATTE
610 620 630 640 650 660
ALSPPKTPSL LPPLGLSQSG PPGLLPSPSF DSKPPTTLLG LIPAPSMVPA TDTKAPPTLQ
670 680 690 700 710 720
AETATKPQAT SAPSPAPKQS FLFGTQNTSP SSPAAPAASS ASPMFKPIFT APPKSEKEGL
730 740 750 760 770 780
TPPGPSVSAT APSSSSLPTT TSTTAPTFQP VFSSMGPPAS VPLPAPFFKQ TTTPATAPTT
790 800 810 820 830 840
TAPLFTGLAS ATSAVAPITS ASPSTDSASK PAFGFGINSV SSSSVSTTTS TATAASQPFL
850 860 870 880 890 900
FGAPQASAAS FTPAMGSIFQ FGKPPALPTT TTVTTFSQSL PTAVPTATSS SAADFSGFGS
910 920 930 940 950 960
TLATSAPATS SQPTLTFSNT STPTFNIPFG SSAKSPLPSY PGANPQPAFG AAEGQPPGAA
970 980 990 1000 1010 1020
KPALTPSFGS SFTFGNSAAP APATAPTPAP ASTIKIVPAH VPTPIQPTFG GATHSAFGLK
1030 1040 1050 1060 1070 1080
ATASAFGAPA SSQPAFGGST AVFSFGAATS SGFGATTQTA SSGSSSSVFG STTPSPFTFG
1090 1100 1110 1120 1130 1140
GSAAPAGSGS FGINVATPGS SATTGAFSFG AGQSGSTATS TPFTGGLGQN ALGTTGQSTP
1150 1160 1170 1180 1190 1200
FAFNVGSTTE SKPVFGGTAT PTFGQNTPAP GVGTSGSSLS FGASSAPAQG FVGVGPFGSA
1210 1220
APSFSIGAGS KTPGARQRLQ ARRQHTRKK
Protein Neighborhood
Domains & Features
3 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
A8CG34-1-unknown | MSPAAA... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
A8CG34-243-unknown | MVCSPV... | 243 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt83957 | |||
A8CG34-354-unknown | NSQSSD... | 354 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13689 | |||
A8CG34-354-unknown | NSQSSD... | 354 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt143058 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...LKRGLN | 353 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13689 | |||
...LKRGLN | 353 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt126278 | |||
...HTRKK | 1229 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...HTRKK | 1229 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt79575 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAM_HUMAN | 353 | RGLN.|.NSQS | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|