P51124: Granzyme M
Protein names | - Granzyme M - 3.4.21.- - Met-1 serine protease - Hu-Met-1 - Met-ase - Natural killer cell granular protease |
---|---|
Gene names | GZMM |
Organism | Homo sapiens |
Protease Family | S01.139 |
Protease ID | S01.139 |
Chromosome location | |
UniProt ID | P51124 |
3
N-termini
3
C-termini
1
Cleavages
1497
Substrates
Sequence
10 20 30 40 50 60
MEACVSSLLV LALGALSVGS SFGTQIIGGR EVIPHSRPYM ASLQRNGSHL CGGVLVHPKW
70 80 90 100 110 120
VLTAAHCLAQ RMAQLRLVLG LHTLDSPGLT FHIKAAIQHP RYKPVPALEN DLALLQLDGK
130 140 150 160 170 180
VKPSRTIRPL ALPSKRQVVA AGTRCSMAGW GLTHQGGRLS RVLRELDLQV LDTRMCNNSR
190 200 210 220 230 240
FWNGSLSPSM VCLAADSKDQ APCKGDSGGP LVCGKGRVLA RVLSFSSRVC TDIFKPPVAT
250
AVAPYVSWIR KVTGRSA
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
3 N-termini - 3 C-termini - 1 Cleavages - 1497 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P51124-24-unknown | TQIIGG... | 24 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P51124-26-unknown | IIGGRE... | 26 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P51124-248-unknown | WIRKVT... | 248 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14183 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...FKPPVA | 238 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000476255 | |||
...APYVSW | 247 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14183 | |||
...TGRSA | 257 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
GRAM_HUMAN | 247 | YVSW.|.WIRK | inferred from experiment | unknown | MEROPS | Bovenschen N | de Poot SA et al.:Human and mouse granzyme M disp... (S01.139) | 21564021, |