Q15050: Ribosome biogenesis regulatory protein homolog

General Information

Protein names	- Ribosome biogenesis regulatory protein homolog
Gene names	RRS1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q15050

5 N-termini

4 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEGQSVEELL AKAEQDEAEK LQRITVHKEL ELQFDLGNLL ASDRNPPTGL RCAGPTPEAE
        70         80         90        100        110        120
LQALARDNTQ LLINQLWQLP TERVEEAIVA RLPEPTTRLP REKPLPRPRP LTRWQQFARL
       130        140        150        160        170        180
KGIRPKKKTN LVWDEVSGQW RRRWGYQRAR DDTKEWLIEV PGNADPLEDQ FAKRIQAKKE
       190        200        210        220        230        240
RVAKNELNRL RNLARAHKMQ LPSAAGLHPT GHQSKEELGR AMQVAKVSTA SVGRFQERLP
       250        260        270        280        290        300
KEKVPRGSGK KRKFQPLFGD FAAEKKNQLE LLRVMNSKKP QLDVTRATNK QMREEDQEEA
       310        320        330        340        350        360
AKRRKMSQKG KRKGGRQGPG GKRKGGPPSQ GGKRKGGLGG KMNSGPPGLG GKRKGGQRPG

GKRRK

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q15050-1-Acetylation	MEGQSV...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q15050-1-Acetylation	MEGQSV...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q15050-1-Acetylation	MEGQSV...	1	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
Q15050-1-Acetylation	MEGQSV...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q15050-5-unknown	SVEELL...	5		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14520
Q15050-11-unknown	AKAEQD...	11		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14521
Q15050-258-unknown	FGDFAA...	258		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14522
Q15050-261-unknown	FAAEKK...	261		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC12343

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VEELLA	10	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14521
...KFQPLF	257	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14522
...PLFGDF	260	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12343
...GKRRK	365	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	4	EGQS.\|.SVEE	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	10	ELLA.\|.AKAE	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	257	QPLF.\|.FGDF	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAB_HUMAN	260	FGDF.\|.FAAE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)