TopFIND 4.0

P10144: Granzyme B

General Information

Protein names
- Granzyme B
- 3.4.21.79
- C11
- CTLA-1
- Cathepsin G-like 1
- CTSGL1
- Cytotoxic T-lymphocyte proteinase 2
- Lymphocyte protease
- Fragmentin-2
- Granzyme-2
- Human lymphocyte protein
- HLP
- SECT
- T-cell serine protease 1-3E
Gene names GZMB
Organism Homo sapiens
Protease Family S01.010
Protease ID S01.010
Chromosome location
UniProt ID P10144

1

N-termini

2

C-termini

1

Cleavages

3047

Substrates

Sequence

        10         20         30         40         50         60 
MQPILLLLAF LLLPRADAGE IIGGHEAKPH SRPYMAYLMI WDQKSLKRCG GFLIRDDFVL 
        70         80         90        100        110        120 
TAAHCWGSSI NVTLGAHNIK EQEPTQQFIP VKRPIPHPAY NPKNFSNDIM LLQLERKAKR 
       130        140        150        160        170        180 
TRAVQPLRLP SNKAQVKPGQ TCSVAGWGQT APLGKHSHTL QEVKMTVQED RKCESDLRHY 
       190        200        210        220        230        240 
YDSTIELCVG DPEIKKTSFK GDSGGPLVCN KVAQGIVSYG RNNGMPPRAC TKVSSFVHWI 
   
KKTMKRY

Isoforms



Sequence View



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(REFRESH)

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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 1 Cleavages - 3047 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P10144-21-unknown IIGGHE... 21 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P10144-21-unknown IIGGHE... 21 inferred from cleavage unknown TopFIND Inferred from cleavage TC4313

C-termini

Cleavages

Substrates