P35226: Polycomb complex protein BMI-1

General Information

Protein names	- Polycomb complex protein BMI-1 - Polycomb group RING finger protein 4 - RING finger protein 51
Gene names	BMI1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P35226

3 N-termini

6 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MHRTTRIKIT ELNPHLMCVL CGGYFIDATT IIECLHSFCK TCIVRYLETS KYCPICDVQV
        70         80         90        100        110        120
HKTRPLLNIR SDKTLQDIVY KLVPGLFKNE MKRRRDFYAA HPSADAANGS NEDRGEVADE
       130        140        150        160        170        180
DKRIITDDEI ISLSIEFFDQ NRLDRKVNKD KEKSKEEVND KRYLRCPAAM TVMHLRKFLR
       190        200        210        220        230        240
SKMDIPNTFQ IDVMYEEEPL KDYYTLMDIA YIYTWRRNGP LPLKYRVRPT CKRMKISHQR
       250        260        270        280        290        300
DGLTNAGELE SDSGSDKANS PAGGIPSTSS CLPSPSTPVQ SPHPQFPHIS STMNGTSNSP
       310        320
SGNHQSSFAN RPRKSSVNGS SATSSG

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

3 N-termini - 6 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P35226-1-unknown	MHRTTR...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P35226-24-unknown	YFIDAT...	24	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000390768
P35226-253-unknown	SGSDKA...	253	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11453

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...HPSADA	105	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000399220
...KVNKDK	150	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000397912
...ELESDS	252	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11453
...PSTPVQ	279	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000390768
...ATSSG	326		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...ATSSG	326		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...ATSSG	326	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...ATSSG	326		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...ATSSG	326		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAB_HUMAN	252	ESDS.\|.SGSD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)