Q15435: Protein phosphatase 1 regulatory subunit 7

General Information

Protein names	- Protein phosphatase 1 regulatory subunit 7 - Protein phosphatase 1 regulatory subunit 22
Gene names	PPP1R7
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q15435

6 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Protein phosphatase 1 regulatory subunit 7 - Isoform 3 of Protein phosphatase 1 regulatory subunit 7 - Isoform 4 of Protein phosphatase 1 regulatory subunit 7 - Isoform 5 of Protein phosphatase 1 regulatory subunit 7

Sequence View

        10         20         30         40         50         60
MAAERGAGQQ QSQEMMEVDR RVESEESGDE EGKKHSSGIV ADLSEQSLKD GEERGEEDPE
        70         80         90        100        110        120
EEHELPVDME TINLDRDAED VDLNHYRIGK IEGFEVLKKV KTLCLRQNLI KCIENLEELQ
       130        140        150        160        170        180
SLRELDLYDN QIKKIENLEA LTELEILDIS FNLLRNIEGV DKLTRLKKLF LVNNKISKIE
       190        200        210        220        230        240
NLSNLHQLQM LELGSNRIRA IENIDTLTNL ESLFLGKNKI TKLQNLDALT NLTVLSMQSN
       250        260        270        280        290        300
RLTKIEGLQN LVNLRELYLS HNGIEVIEGL ENNNKLTMLD IASNRIKKIE NISHLTELQE
       310        320        330        340        350        360
FWMNDNLLES WSDLDELKGA RSLETVYLER NPLQKDPQYR RKVMLALPSV RQIDATFVRF

        10         20         30         40         50         60
MAAERGAGQQ QSQEMMEVDR RVESEESGDE EGKKHSSGIV ADLSEQSLKD GEERGEEDPE
        70         80         90        100        110        120
EEHELPVDME TINLDRDAED VDLNHYRIGK IEGFEVLKKV KTLCLRQNLI KCIENLEELQ
       130        140        150        160        170        180
SLRELDLYDN QIKKIENLEA LTELEILDIS FNLLRNIEGV DKLTRLKKLF LVNNKISKIE
       190        200        210        220        230        240
NLSNLHQLQM LELGSNRIRA IENIDTLTNL ESLFLGKNKI TKLQNLDALT NLTVLSMQSN
       250        260        270        280        290        300
RLTKIEGLQN LVNLRELYLS HNGIEVIEGL ENNNKLTMLD IASNRIKKIE NISHLTELQE
       310        320        330        340        350        360
FWMNDNLLES WSDLDELKGA RSLETVYLER NPLQKDPQYR RKVMLALPSV RQIDATFVRF

        10         20         30         40         50         60
MAAERGAGQQ QSQEMMEVDR RVESEESGDE EGKKHSSGIV ADLSEQSLKD GEERGEEDPE
        70         80         90        100        110        120
EEHELPVDME TINLDRDAED VDLNHYRIGK IEGFEVLKKV KTLCLRQNLI KCIENLEELQ
       130        140        150        160        170        180
SLRELDLYDN QIKKIENLEA LTELEILDIS FNLLRNIEGV DKLTRLKKLF LVNNKISKIE
       190        200        210        220        230        240
NLSNLHQLQM LELGSNRIRA IENIDTLTNL ESLFLGKNKI TKLQNLDALT NLTVLSMQSN
       250        260        270        280        290        300
RLTKIEGLQN LVNLRELYLS HNGIEVIEGL ENNNKLTMLD IASNRIKKIE NISHLTELQE
       310        320        330        340        350        360
FWMNDNLLES WSDLDELKGA RSLETVYLER NPLQKDPQYR RKVMLALPSV RQIDATFVRF

        10         20         30         40         50         60
MAAERGAGQQ QSQEMMEVDR RVESEESGDE EGKKHSSGIV ADLSEQSLKD GEERGEEDPE
        70         80         90        100        110        120
EEHELPVDME TINLDRDAED VDLNHYRIGK IEGFEVLKKV KTLCLRQNLI KCIENLEELQ
       130        140        150        160        170        180
SLRELDLYDN QIKKIENLEA LTELEILDIS FNLLRNIEGV DKLTRLKKLF LVNNKISKIE
       190        200        210        220        230        240
NLSNLHQLQM LELGSNRIRA IENIDTLTNL ESLFLGKNKI TKLQNLDALT NLTVLSMQSN
       250        260        270        280        290        300
RLTKIEGLQN LVNLRELYLS HNGIEVIEGL ENNNKLTMLD IASNRIKKIE NISHLTELQE
       310        320        330        340        350        360
FWMNDNLLES WSDLDELKGA RSLETVYLER NPLQKDPQYR RKVMLALPSV RQIDATFVRF

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q15435-2-unknown	MAAERG...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q15435-1-unknown	MAAERG...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85843
Q15435-2-Acetylation	AAERGA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q15435-2-Acetylation	AAERGA...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110081
Q15435-6-unknown	GAGQQQ...	6		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10318
Q15435-6-unknown	GAGQQQ...	6		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt194728
Q15435-39-unknown	IVADLS...	39		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4098
Q15435-39-unknown	IVADLS...	39		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt138222
Q15435-43-unknown	LSEQSL...	43		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12368
Q15435-43-unknown	LSEQSL...	43		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt138592

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...MAAERG	5	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10318
...KHSSGI	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4098
...KHSSGI	38	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt121252
...GIVADL	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC12368
...GIVADL	42	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt121642
...TFVRF	360	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...TFVRF	360	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt81460

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	5	AERG.\|.GAGQ	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
CATB_HUMAN	38	SSGI.\|.IVAD	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAB_HUMAN	42	VADL.\|.LSEQ	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)