TopFIND 4.0

P07858: Cathepsin B

General Information

Protein names
- Cathepsin B
- 3.4.22.1 {ECO:0000269|PubMed:12220505, ECO:0000269|PubMed:3972105}
- APP secretase
- APPS
- Cathepsin B1
- Cathepsin B light chain {ECO:0000303|PubMed:3972105}
- Cathepsin B heavy chain {ECO:0000303|PubMed:3972105}

Gene names CTSB
Organism Homo sapiens
Protease Family C01.060
Protease ID C01.060
Chromosome location
UniProt ID P07858

12

N-termini

22

C-termini

7

Cleavages

1076

Substrates

Sequence

        10         20         30         40         50         60 
MWQLWASLCC LLVLANARSR PSFHPLSDEL VNYVNKRNTT WQAGHNFYNV DMSYLKRLCG 
        70         80         90        100        110        120 
TFLGGPKPPQ RVMFTEDLKL PASFDAREQW PQCPTIKEIR DQGSCGSCWA FGAVEAISDR 
       130        140        150        160        170        180 
ICIHTNAHVS VEVSAEDLLT CCGSMCGDGC NGGYPAEAWN FWTRKGLVSG GLYESHVGCR 
       190        200        210        220        230        240 
PYSIPPCEHH VNGSRPPCTG EGDTPKCSKI CEPGYSPTYK QDKHYGYNSY SVSNSEKDIM 
       250        260        270        280        290        300 
AEIYKNGPVE GAFSVYSDFL LYKSGVYQHV TGEMMGGHAI RILGWGVENG TPYWLVANSW 
       310        320        330    
NTDWGDNGFF KILRGQDHCG IESEVVAGIP RTDQYWEKI

Isoforms



Sequence View



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(REFRESH)

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Protein Neighborhood

Domains & Features

12 N-termini - 22 C-termini - 7 Cleavages - 1076 Substrates

N-termini

C-termini

Cleavages

Substrates