TopFIND 4.0

P34949: Mannose-6-phosphate isomerase

General Information

Protein names
- Mannose-6-phosphate isomerase
- 5.3.1.8
- Phosphohexomutase
- Phosphomannose isomerase
- PMI
Gene names MPI
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P34949

4

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAAPRVFPLS CAVQQYAWGK MGSNSEVARL LASSDPLAQI AEDKPYAELW MGTHPRGDAK 
        70         80         90        100        110        120 
ILDNRISQKT LSQWIAENQD SLGSKVKDTF NGNLPFLFKV LSVETPLSIQ AHPNKELAEK 
       130        140        150        160        170        180 
LHLQAPQHYP DANHKPEMAI ALTPFQGLCG FRPVEEIVTF LKKVPEFQFL IGDEAATHLK 
       190        200        210        220        230        240 
QTMSHDSQAV ASSLQSCFSH LMKSEKKVVV EQLNLLVKRI SQQAAAGNNM EDIFGELLLQ 
       250        260        270        280        290        300 
LHQQYPGDIG CFAIYFLNLL TLKPGEAMFL EANVPHAYLK GDCVECMACS DNTVRAGLTP 
       310        320        330        340        350        360 
KFIDVPTLCE MLSYTPSSSK DRLFLPTRSQ EDPYLSIYDP PVPDFTIMKT EVPGSVTEYK 
       370        380        390        400        410        420 
VLALDSASIL LMVQGTVIAS TPTTQTPIPL QRGGVLFIGA NESVSLKLTE PKDLLIFRAC 
   
CLL

Isoforms

- Isoform 2 of Mannose-6-phosphate isomerase

Sequence View

        10         20         30         40         50         60 
MAAPRVFPLS CAVQQYAWGK MGSNSEVARL LASSDPLAQI AEDKPYAELW MGTHPRGDAK 
        70         80         90        100        110        120 
ILDNRISQKT LSQWIAENQD SLGSKVKDTF NGNLPFLFKV LSVETPLSIQ AHPNKELAEK 
       130        140        150        160        170        180 
LHLQAPQHYP DANHKPEMAI ALTPFQGLCG FRPVEEIVTF LKKVPEFQFL IGDEAATHLK 
       190        200        210        220        230        240 
QTMSHDSQAV ASSLQSCFSH LMKSEKKVVV EQLNLLVKRI SQQAAAGNNM EDIFGELLLQ 
       250        260        270        280        290        300 
LHQQYPGDIG CFAIYFLNLL TLKPGEAMFL EANVPHAYLK GDCVECMACS DNTVRAGLTP 
       310        320        330        340        350        360 
KFIDVPTLCE MLSYTPSSSK DRLFLPTRSQ EDPYLSIYDP PVPDFTIMKT EVPGSVTEYK 
       370        380        390        400        410        420 
VLALDSASIL LMVQGTVIAS TPTTQTPIPL QRGGVLFIGA NESVSLKLTE PKDLLIFRAC 
   
CLL



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)