Q14141: Septin-6
Protein names | - Septin-6 |
---|---|
Gene names | SEPT6 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q14141 |
5
N-termini
4
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MAATDIARQV GEGCRTVPLA GHVGFDSLPD QLVNKSVSQG FCFNILCVGE TGLGKSTLMD
70 80 90 100 110 120
TLFNTKFEGE PATHTQPGVQ LQSNTYDLQE SNVRLKLTIV STVGFGDQIN KEDSYKPIVE
130 140 150 160 170 180
FIDAQFEAYL QEELKIRRVL HTYHDSRIHV CLYFIAPTGH SLKSLDLVTM KKLDSKVNII
190 200 210 220 230 240
PIIAKADAIS KSELTKFKIK ITSELVSNGV QIYQFPTDDE SVAEINGTMN AHLPFAVIGS
250 260 270 280 290 300
TEELKIGNKM MRARQYPWGT VQVENEAHCD FVKLREMLIR VNMEDLREQT HTRHYELYRR
310 320 330 340 350 360
CKLEEMGFKD TDPDSKPFSL QETYEAKRNE FLGELQKKEE EMRQMFVQRV KEKEAELKEA
370 380 390 400 410 420
EKELHEKFDR LKKLHQDEKK KLEDKKKSLD DEVNAFKQRK TAAELLQSQG SQAGGSQTLK
430
RDKEKKNNPW LCTE
Isoforms
- Isoform I of Septin-6 - Isoform IV of Septin-6 - Isoform V of Septin-6Sequence View
10 20 30 40 50 60
MAATDIARQV GEGCRTVPLA GHVGFDSLPD QLVNKSVSQG FCFNILCVGE TGLGKSTLMD
70 80 90 100 110 120
TLFNTKFEGE PATHTQPGVQ LQSNTYDLQE SNVRLKLTIV STVGFGDQIN KEDSYKPIVE
130 140 150 160 170 180
FIDAQFEAYL QEELKIRRVL HTYHDSRIHV CLYFIAPTGH SLKSLDLVTM KKLDSKVNII
190 200 210 220 230 240
PIIAKADAIS KSELTKFKIK ITSELVSNGV QIYQFPTDDE SVAEINGTMN AHLPFAVIGS
250 260 270 280 290 300
TEELKIGNKM MRARQYPWGT VQVENEAHCD FVKLREMLIR VNMEDLREQT HTRHYELYRR
310 320 330 340 350 360
CKLEEMGFKD TDPDSKPFSL QETYEAKRNE FLGELQKKEE EMRQMFVQRV KEKEAELKEA
370 380 390 400 410 420
EKELHEKFDR LKKLHQDEKK KLEDKKKSLD DEVNAFKQRK TAAELLQSQG SQAGGSQTLK
430
RDKEKKNNPW LCTE
10 20 30 40 50 60
MAATDIARQV GEGCRTVPLA GHVGFDSLPD QLVNKSVSQG FCFNILCVGE TGLGKSTLMD
70 80 90 100 110 120
TLFNTKFEGE PATHTQPGVQ LQSNTYDLQE SNVRLKLTIV STVGFGDQIN KEDSYKPIVE
130 140 150 160 170 180
FIDAQFEAYL QEELKIRRVL HTYHDSRIHV CLYFIAPTGH SLKSLDLVTM KKLDSKVNII
190 200 210 220 230 240
PIIAKADAIS KSELTKFKIK ITSELVSNGV QIYQFPTDDE SVAEINGTMN AHLPFAVIGS
250 260 270 280 290 300
TEELKIGNKM MRARQYPWGT VQVENEAHCD FVKLREMLIR VNMEDLREQT HTRHYELYRR
310 320 330 340 350 360
CKLEEMGFKD TDPDSKPFSL QETYEAKRNE FLGELQKKEE EMRQMFVQRV KEKEAELKEA
370 380 390 400 410 420
EKELHEKFDR LKKLHQDEKK KLEDKKKSLD DEVNAFKQRK TAAELLQSQG SQAGGSQTLK
430
RDKEKKNNPW LCTE
10 20 30 40 50 60
MAATDIARQV GEGCRTVPLA GHVGFDSLPD QLVNKSVSQG FCFNILCVGE TGLGKSTLMD
70 80 90 100 110 120
TLFNTKFEGE PATHTQPGVQ LQSNTYDLQE SNVRLKLTIV STVGFGDQIN KEDSYKPIVE
130 140 150 160 170 180
FIDAQFEAYL QEELKIRRVL HTYHDSRIHV CLYFIAPTGH SLKSLDLVTM KKLDSKVNII
190 200 210 220 230 240
PIIAKADAIS KSELTKFKIK ITSELVSNGV QIYQFPTDDE SVAEINGTMN AHLPFAVIGS
250 260 270 280 290 300
TEELKIGNKM MRARQYPWGT VQVENEAHCD FVKLREMLIR VNMEDLREQT HTRHYELYRR
310 320 330 340 350 360
CKLEEMGFKD TDPDSKPFSL QETYEAKRNE FLGELQKKEE EMRQMFVQRV KEKEAELKEA
370 380 390 400 410 420
EKELHEKFDR LKKLHQDEKK KLEDKKKSLD DEVNAFKQRK TAAELLQSQG SQAGGSQTLK
430
RDKEKKNNPW LCTE
Protein Neighborhood
Domains & Features
5 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q14141-2-unknown | MAATDI... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q14141-1-unknown | MAATDI... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt89292 | |||
Q14141-1-unknown | MAATDI... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt89293 | |||
Q14141-1-unknown | MAATDI... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt89294 | |||
Q14141-2-Acetylation | AATDIA... | 2 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
Q14141-2-Acetylation | AATDIA... | 2 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345 | ||
Q14141-2-Acetylation | AATDIA... | 2 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345 | ||
Q14141-2-Acetylation | AATDIA... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt110244 | ||
Q14141-2-Acetylation | AATDIA... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt110245 | ||
Q14141-2-Acetylation | AATDIA... | 2 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt110246 | ||
Q14141-22-unknown | HVGFDS... | 22 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4038 | |||
Q14141-22-unknown | HVGFDS... | 22 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt137023 | |||
Q14141-22-unknown | HVGFDS... | 22 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt137025 | |||
Q14141-22-unknown | HVGFDS... | 22 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt137026 | |||
Q14141-408-unknown | SQGSQA... | 408 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6385 | |||
Q14141-408-unknown | SQGSQA... | 408 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152138 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...VPLAGH | 21 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC4038 | |||
...VPLAGH | 21 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt119867 | |||
...VPLAGH | 21 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt119869 | |||
...VPLAGH | 21 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt119870 | |||
...AELLQS | 407 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6385 | |||
...AELLQS | 407 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt135546 | |||
...AELLQS | 407 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt135547 | |||
...KEKKNN | 427 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt84910 | |||
...KEKKNN | 427 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt92733 | |||
...WLCTE | 434 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATB_HUMAN | 21 | LAGH.|.HVGF | inferred from experiment | unknown | MEROPS | Schilling O | Biniossek ML et al.:Proteomic identification of pro... (C01.060) | 21967108, |
CATL1_HUMAN | 407 | LLQS.|.SQGS | inferred from experiment | unknown | MEROPS | Schilling O | Biniossek ML et al.:Proteomic identification of pro... (C01.060) | 21967108, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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