P30626: Sorcin

General Information

Protein names	- Sorcin - 22 kDa protein - CP-22 - CP22 - V19
Gene names	SRI
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P30626

4 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Sorcin - Isoform 3 of Sorcin

Sequence View

        10         20         30         40         50         60
MAYPGHPGAG GGYYPGGYGG APGGPAFPGQ TQDPLYGYFA AVAGQDGQID ADELQRCLTQ
        70         80         90        100        110        120
SGIAGGYKPF NLETCRLMVS MLDRDMSGTM GFNEFKELWA VLNGWRQHFI SFDTDRSGTV
       130        140        150        160        170        180
DPQELQKALT TMGFRLSPQA VNSIAKRYST NGKITFDDYI ACCVKLRALT DSFRRRDTAQ
       190
QGVVNFPYDD FIQCVMSV         10         20         30         40         50         60
MAYPGHPGAG GGYYPGGYGG APGGPAFPGQ TQDPLYGYFA AVAGQDGQID ADELQRCLTQ
        70         80         90        100        110        120
SGIAGGYKPF NLETCRLMVS MLDRDMSGTM GFNEFKELWA VLNGWRQHFI SFDTDRSGTV
       130        140        150        160        170        180
DPQELQKALT TMGFRLSPQA VNSIAKRYST NGKITFDDYI ACCVKLRALT DSFRRRDTAQ
       190
QGVVNFPYDD FIQCVMSV

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Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P30626-1-unknown	MAYPGH...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P30626-41-unknown	AVAGQD...	41	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171095
P30626-41-unknown	AVAGQD...	41	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171096
P30626-41-	AVAGQD...	41		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P30626-41-	AVAGQD...	41		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P30626-41-	AVAGQD...	41		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P30626-41-	AVAGQD...	41		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P30626-41-	AVAGQD...	41		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P30626-63-unknown	IAGGYK...	63	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3766
P30626-63-unknown	IAGGYK...	63	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139024
P30626-63-unknown	IAGGYK...	63	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139025

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...LTQSGI	62	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3766
...LTQSGI	62	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt122093
...LTQSGI	62	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt122094
...CVMSV	198		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...CVMSV	198		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...CVMSV	198	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...CVMSV	198	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt85881
...CVMSV	198		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...CVMSV	198		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATB_HUMAN	62	QSGI.\|.IAGG	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)