A5YKK6: CCR4-NOT transcription complex subunit 1
Protein names | - CCR4-NOT transcription complex subunit 1 - CCR4-associated factor 1 - Negative regulator of transcription subunit 1 homolog - NOT1H - hNOT1 |
---|---|
Gene names | CNOT1 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | A5YKK6 |
4
N-termini
4
C-termini
4
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MNLDSLSLAL SQISYLVDNL TKKNYRASQQ EIQHIVNRHG PEADRHLLRC LFSHVDFSGD
70 80 90 100 110 120
GKSSGKDFHQ TQFLIQECAL LITKPNFIST LSYAIDNPLH YQKSLKPAPH LFAQLSKVLK
130 140 150 160 170 180
LSKVQEVIFG LALLNSSSSD LRGFAAQFIK QKLPDLLRSY IDADVSGNQE GGFQDIAIEV
190 200 210 220 230 240
LHLLLSHLLF GQKGAFGVGQ EQIDAFLKTL RRDFPQERCP VVLAPLLYPE KRDILMDRIL
250 260 270 280 290 300
PDSGGVAKTM MESSLADFMQ EVGYGFCASI EECRNIIVQF GVREVTAAQV ARVLGMMART
310 320 330 340 350 360
HSGLTDGIPL QSISAPGSGI WSDGKDKSDG AQAHTWNVEV LIDVLKELNP SLNFKEVTYE
370 380 390 400 410 420
LDHPGFQIRD SKGLHNVVYG IQRGLGMEVF PVDLIYRPWK HAEGQLSFIQ HSLINPEIFC
430 440 450 460 470 480
FADYPCHTVA TDILKAPPED DNREIATWKS LDLIESLLRL AEVGQYEQVK QLFSFPIKHC
490 500 510 520 530 540
PDMLVLALLQ INTSWHTLRH ELISTLMPIF LGNHPNSAII LHYAWHGQGQ SPSIRQLIMH
550 560 570 580 590 600
AMAEWYMRGE QYDQAKLSRI LDVAQDLKAL SMLLNGTPFA FVIDLAALAS RREYLKLDKW
610 620 630 640 650 660
LTDKIREHGE PFIQACMTFL KRRCPSILGG LAPEKDQPKS AQLPPETLAT MLACLQACAG
670 680 690 700 710 720
SVSQELSETI LTMVANCSNV MNKARQPPPG VMPKGRPPSA SSLDAISPVQ IDPLAGMTSL
730 740 750 760 770 780
SIGGSAAPHT QSMQGFPPNL GSAFSTPQSP AKAFPPLSTP NQTTAFSGIG GLSSQLPVGG
790 800 810 820 830 840
LGTGSLTGIG TGALGLPAVN NDPFVQRKLG TSGLNQPTFQ QSKMKPSDLS QVWPEANQHF
850 860 870 880 890 900
SKEIDDEANS YFQRIYNHPP HPTMSVDEVL EMLQRFKDST IKREREVFNC MLRNLFEEYR
910 920 930 940 950 960
FFPQYPDKEL HITACLFGGI IEKGLVTYMA LGLALRYVLE ALRKPFGSKM YYFGIAALDR
970 980 990 1000 1010 1020
FKNRLKDYPQ YCQHLASISH FMQFPHHLQE YIEYGQQSRD PPVKMQGSIT TPGSIALAQA
1030 1040 1050 1060 1070 1080
QAQAQVPAKA PLAGQVSTMV TTSTTTTVAK TVTVTRPTGV SFKKDVPPSI NTTNIDTLLV
1090 1100 1110 1120 1130 1140
ATDQTERIVE PPENIQEKIA FIFNNLSQSN MTQKVEELKE TVKEEFMPWV SQYLVMKRVS
1150 1160 1170 1180 1190 1200
IEPNFHSLYS NFLDTLKNPE FNKMVLNETY RNIKVLLTSD KAAANFSDRS LLKNLGHWLG
1210 1220 1230 1240 1250 1260
MITLAKNKPI LHTDLDVKSL LLEAYVKGQQ ELLYVVPFVA KVLESSIRSV VFRPPNPWTM
1270 1280 1290 1300 1310 1320
AIMNVLAELH QEHDLKLNLK FEIEVLCKNL ALDINELKPG NLLKDKDRLK NLDEQLSAPK
1330 1340 1350 1360 1370 1380
KDVKQPEELP PITTTTTSTT PATNTTCTAT VPPQPQYSYH DINVYSLAGL APHITLNPTI
1390 1400 1410 1420 1430 1440
PLFQAHPQLK QCVRQAIERA VQELVHPVVD RSIKIAMTTC EQIVRKDFAL DSEESRMRIA
1450 1460 1470 1480 1490 1500
AHHMMRNLTA GMAMITCREP LLMSISTNLK NSFASALRTA SPQQREMMDQ AAAQLAQDNC
1510 1520 1530 1540 1550 1560
ELACCFIQKT AVEKAGPEMD KRLATEFELR KHARQEGRRY CDPVVLTYQA ERMPEQIRLK
1570 1580 1590 1600 1610 1620
VGGVDPKQLA VYEEFARNVP GFLPTNDLSQ PTGFLAQPMK QAWATDDVAQ IYDKCITELE
1630 1640 1650 1660 1670 1680
QHLHAIPPTL AMNPQAQALR SLLEVVVLSR NSRDAIAALG LLQKAVEGLL DATSGADADL
1690 1700 1710 1720 1730 1740
LLRYRECHLL VLKALQDGRA YGSPWCNKQI TRCLIECRDE YKYNVEAVEL LIRNHLVNMQ
1750 1760 1770 1780 1790 1800
QYDLHLAQSM ENGLNYMAVA FAMQLVKILL VDERSVAHVT EADLFHTIET LMRINAHSRG
1810 1820 1830 1840 1850 1860
NAPEGLPQLM EVVRSNYEAM IDRAHGGPNF MMHSGISQAS EYDDPPGLRE KAEYLLREWV
1870 1880 1890 1900 1910 1920
NLYHSAAAGR DSTKAFSAFV GQMHQQGILK TDDLITRFFR LCTEMCVEIS YRAQAEQQHN
1930 1940 1950 1960 1970 1980
PAANPTMIRA KCYHNLDAFV RLIALLVKHS GEATNTVTKI NLLNKVLGIV VGVLLQDHDV
1990 2000 2010 2020 2030 2040
RQSEFQQLPY HRIFIMLLLE LNAPEHVLET INFQTLTAFC NTFHILRPTK APGFVYAWLE
2050 2060 2070 2080 2090 2100
LISHRIFIAR MLAHTPQQKG WPMYAQLLID LFKYLAPFLR NVELTKPMQI LYKGTLRVLL
2110 2120 2130 2140 2150 2160
VLLHDFPEFL CDYHYGFCDV IPPNCIQLRN LILSAFPRNM RLPDPFTPNL KVDMLSEINI
2170 2180 2190 2200 2210 2220
APRILTNFTG VMPPQFKKDL DSYLKTRSPV TFLSDLRSNL QVSNEPGNRY NLQLINALVL
2230 2240 2250 2260 2270 2280
YVGTQAIAHI HNKGSTPSMS TITHSAHMDI FQNLAVDLDT EGRYLFLNAI ANQLRYPNSH
2290 2300 2310 2320 2330 2340
THYFSCTMLY LFAEANTEAI QEQITRVLLE RLIVNRPHPW GLLITFIELI KNPAFKFWNH
2350 2360 2370
EFVHCAPEIE KLFQSVAQCC MGQKQAQQVM EGTGAS
Isoforms
- Isoform 2 of CCR4-NOT transcription complex subunit 1 - Isoform 3 of CCR4-NOT transcription complex subunit 1 - Isoform 4 of CCR4-NOT transcription complex subunit 1Sequence View
10 20 30 40 50 60
MNLDSLSLAL SQISYLVDNL TKKNYRASQQ EIQHIVNRHG PEADRHLLRC LFSHVDFSGD
70 80 90 100 110 120
GKSSGKDFHQ TQFLIQECAL LITKPNFIST LSYAIDNPLH YQKSLKPAPH LFAQLSKVLK
130 140 150 160 170 180
LSKVQEVIFG LALLNSSSSD LRGFAAQFIK QKLPDLLRSY IDADVSGNQE GGFQDIAIEV
190 200 210 220 230 240
LHLLLSHLLF GQKGAFGVGQ EQIDAFLKTL RRDFPQERCP VVLAPLLYPE KRDILMDRIL
250 260 270 280 290 300
PDSGGVAKTM MESSLADFMQ EVGYGFCASI EECRNIIVQF GVREVTAAQV ARVLGMMART
310 320 330 340 350 360
HSGLTDGIPL QSISAPGSGI WSDGKDKSDG AQAHTWNVEV LIDVLKELNP SLNFKEVTYE
370 380 390 400 410 420
LDHPGFQIRD SKGLHNVVYG IQRGLGMEVF PVDLIYRPWK HAEGQLSFIQ HSLINPEIFC
430 440 450 460 470 480
FADYPCHTVA TDILKAPPED DNREIATWKS LDLIESLLRL AEVGQYEQVK QLFSFPIKHC
490 500 510 520 530 540
PDMLVLALLQ INTSWHTLRH ELISTLMPIF LGNHPNSAII LHYAWHGQGQ SPSIRQLIMH
550 560 570 580 590 600
AMAEWYMRGE QYDQAKLSRI LDVAQDLKAL SMLLNGTPFA FVIDLAALAS RREYLKLDKW
610 620 630 640 650 660
LTDKIREHGE PFIQACMTFL KRRCPSILGG LAPEKDQPKS AQLPPETLAT MLACLQACAG
670 680 690 700 710 720
SVSQELSETI LTMVANCSNV MNKARQPPPG VMPKGRPPSA SSLDAISPVQ IDPLAGMTSL
730 740 750 760 770 780
SIGGSAAPHT QSMQGFPPNL GSAFSTPQSP AKAFPPLSTP NQTTAFSGIG GLSSQLPVGG
790 800 810 820 830 840
LGTGSLTGIG TGALGLPAVN NDPFVQRKLG TSGLNQPTFQ QSKMKPSDLS QVWPEANQHF
850 860 870 880 890 900
SKEIDDEANS YFQRIYNHPP HPTMSVDEVL EMLQRFKDST IKREREVFNC MLRNLFEEYR
910 920 930 940 950 960
FFPQYPDKEL HITACLFGGI IEKGLVTYMA LGLALRYVLE ALRKPFGSKM YYFGIAALDR
970 980 990 1000 1010 1020
FKNRLKDYPQ YCQHLASISH FMQFPHHLQE YIEYGQQSRD PPVKMQGSIT TPGSIALAQA
1030 1040 1050 1060 1070 1080
QAQAQVPAKA PLAGQVSTMV TTSTTTTVAK TVTVTRPTGV SFKKDVPPSI NTTNIDTLLV
1090 1100 1110 1120 1130 1140
ATDQTERIVE PPENIQEKIA FIFNNLSQSN MTQKVEELKE TVKEEFMPWV SQYLVMKRVS
1150 1160 1170 1180 1190 1200
IEPNFHSLYS NFLDTLKNPE FNKMVLNETY RNIKVLLTSD KAAANFSDRS LLKNLGHWLG
1210 1220 1230 1240 1250 1260
MITLAKNKPI LHTDLDVKSL LLEAYVKGQQ ELLYVVPFVA KVLESSIRSV VFRPPNPWTM
1270 1280 1290 1300 1310 1320
AIMNVLAELH QEHDLKLNLK FEIEVLCKNL ALDINELKPG NLLKDKDRLK NLDEQLSAPK
1330 1340 1350 1360 1370 1380
KDVKQPEELP PITTTTTSTT PATNTTCTAT VPPQPQYSYH DINVYSLAGL APHITLNPTI
1390 1400 1410 1420 1430 1440
PLFQAHPQLK QCVRQAIERA VQELVHPVVD RSIKIAMTTC EQIVRKDFAL DSEESRMRIA
1450 1460 1470 1480 1490 1500
AHHMMRNLTA GMAMITCREP LLMSISTNLK NSFASALRTA SPQQREMMDQ AAAQLAQDNC
1510 1520 1530 1540 1550 1560
ELACCFIQKT AVEKAGPEMD KRLATEFELR KHARQEGRRY CDPVVLTYQA ERMPEQIRLK
1570 1580 1590 1600 1610 1620
VGGVDPKQLA VYEEFARNVP GFLPTNDLSQ PTGFLAQPMK QAWATDDVAQ IYDKCITELE
1630 1640 1650 1660 1670 1680
QHLHAIPPTL AMNPQAQALR SLLEVVVLSR NSRDAIAALG LLQKAVEGLL DATSGADADL
1690 1700 1710 1720 1730 1740
LLRYRECHLL VLKALQDGRA YGSPWCNKQI TRCLIECRDE YKYNVEAVEL LIRNHLVNMQ
1750 1760 1770 1780 1790 1800
QYDLHLAQSM ENGLNYMAVA FAMQLVKILL VDERSVAHVT EADLFHTIET LMRINAHSRG
1810 1820 1830 1840 1850 1860
NAPEGLPQLM EVVRSNYEAM IDRAHGGPNF MMHSGISQAS EYDDPPGLRE KAEYLLREWV
1870 1880 1890 1900 1910 1920
NLYHSAAAGR DSTKAFSAFV GQMHQQGILK TDDLITRFFR LCTEMCVEIS YRAQAEQQHN
1930 1940 1950 1960 1970 1980
PAANPTMIRA KCYHNLDAFV RLIALLVKHS GEATNTVTKI NLLNKVLGIV VGVLLQDHDV
1990 2000 2010 2020 2030 2040
RQSEFQQLPY HRIFIMLLLE LNAPEHVLET INFQTLTAFC NTFHILRPTK APGFVYAWLE
2050 2060 2070 2080 2090 2100
LISHRIFIAR MLAHTPQQKG WPMYAQLLID LFKYLAPFLR NVELTKPMQI LYKGTLRVLL
2110 2120 2130 2140 2150 2160
VLLHDFPEFL CDYHYGFCDV IPPNCIQLRN LILSAFPRNM RLPDPFTPNL KVDMLSEINI
2170 2180 2190 2200 2210 2220
APRILTNFTG VMPPQFKKDL DSYLKTRSPV TFLSDLRSNL QVSNEPGNRY NLQLINALVL
2230 2240 2250 2260 2270 2280
YVGTQAIAHI HNKGSTPSMS TITHSAHMDI FQNLAVDLDT EGRYLFLNAI ANQLRYPNSH
2290 2300 2310 2320 2330 2340
THYFSCTMLY LFAEANTEAI QEQITRVLLE RLIVNRPHPW GLLITFIELI KNPAFKFWNH
2350 2360 2370
EFVHCAPEIE KLFQSVAQCC MGQKQAQQVM EGTGAS
10 20 30 40 50 60
MNLDSLSLAL SQISYLVDNL TKKNYRASQQ EIQHIVNRHG PEADRHLLRC LFSHVDFSGD
70 80 90 100 110 120
GKSSGKDFHQ TQFLIQECAL LITKPNFIST LSYAIDNPLH YQKSLKPAPH LFAQLSKVLK
130 140 150 160 170 180
LSKVQEVIFG LALLNSSSSD LRGFAAQFIK QKLPDLLRSY IDADVSGNQE GGFQDIAIEV
190 200 210 220 230 240
LHLLLSHLLF GQKGAFGVGQ EQIDAFLKTL RRDFPQERCP VVLAPLLYPE KRDILMDRIL
250 260 270 280 290 300
PDSGGVAKTM MESSLADFMQ EVGYGFCASI EECRNIIVQF GVREVTAAQV ARVLGMMART
310 320 330 340 350 360
HSGLTDGIPL QSISAPGSGI WSDGKDKSDG AQAHTWNVEV LIDVLKELNP SLNFKEVTYE
370 380 390 400 410 420
LDHPGFQIRD SKGLHNVVYG IQRGLGMEVF PVDLIYRPWK HAEGQLSFIQ HSLINPEIFC
430 440 450 460 470 480
FADYPCHTVA TDILKAPPED DNREIATWKS LDLIESLLRL AEVGQYEQVK QLFSFPIKHC
490 500 510 520 530 540
PDMLVLALLQ INTSWHTLRH ELISTLMPIF LGNHPNSAII LHYAWHGQGQ SPSIRQLIMH
550 560 570 580 590 600
AMAEWYMRGE QYDQAKLSRI LDVAQDLKAL SMLLNGTPFA FVIDLAALAS RREYLKLDKW
610 620 630 640 650 660
LTDKIREHGE PFIQACMTFL KRRCPSILGG LAPEKDQPKS AQLPPETLAT MLACLQACAG
670 680 690 700 710 720
SVSQELSETI LTMVANCSNV MNKARQPPPG VMPKGRPPSA SSLDAISPVQ IDPLAGMTSL
730 740 750 760 770 780
SIGGSAAPHT QSMQGFPPNL GSAFSTPQSP AKAFPPLSTP NQTTAFSGIG GLSSQLPVGG
790 800 810 820 830 840
LGTGSLTGIG TGALGLPAVN NDPFVQRKLG TSGLNQPTFQ QSKMKPSDLS QVWPEANQHF
850 860 870 880 890 900
SKEIDDEANS YFQRIYNHPP HPTMSVDEVL EMLQRFKDST IKREREVFNC MLRNLFEEYR
910 920 930 940 950 960
FFPQYPDKEL HITACLFGGI IEKGLVTYMA LGLALRYVLE ALRKPFGSKM YYFGIAALDR
970 980 990 1000 1010 1020
FKNRLKDYPQ YCQHLASISH FMQFPHHLQE YIEYGQQSRD PPVKMQGSIT TPGSIALAQA
1030 1040 1050 1060 1070 1080
QAQAQVPAKA PLAGQVSTMV TTSTTTTVAK TVTVTRPTGV SFKKDVPPSI NTTNIDTLLV
1090 1100 1110 1120 1130 1140
ATDQTERIVE PPENIQEKIA FIFNNLSQSN MTQKVEELKE TVKEEFMPWV SQYLVMKRVS
1150 1160 1170 1180 1190 1200
IEPNFHSLYS NFLDTLKNPE FNKMVLNETY RNIKVLLTSD KAAANFSDRS LLKNLGHWLG
1210 1220 1230 1240 1250 1260
MITLAKNKPI LHTDLDVKSL LLEAYVKGQQ ELLYVVPFVA KVLESSIRSV VFRPPNPWTM
1270 1280 1290 1300 1310 1320
AIMNVLAELH QEHDLKLNLK FEIEVLCKNL ALDINELKPG NLLKDKDRLK NLDEQLSAPK
1330 1340 1350 1360 1370 1380
KDVKQPEELP PITTTTTSTT PATNTTCTAT VPPQPQYSYH DINVYSLAGL APHITLNPTI
1390 1400 1410 1420 1430 1440
PLFQAHPQLK QCVRQAIERA VQELVHPVVD RSIKIAMTTC EQIVRKDFAL DSEESRMRIA
1450 1460 1470 1480 1490 1500
AHHMMRNLTA GMAMITCREP LLMSISTNLK NSFASALRTA SPQQREMMDQ AAAQLAQDNC
1510 1520 1530 1540 1550 1560
ELACCFIQKT AVEKAGPEMD KRLATEFELR KHARQEGRRY CDPVVLTYQA ERMPEQIRLK
1570 1580 1590 1600 1610 1620
VGGVDPKQLA VYEEFARNVP GFLPTNDLSQ PTGFLAQPMK QAWATDDVAQ IYDKCITELE
1630 1640 1650 1660 1670 1680
QHLHAIPPTL AMNPQAQALR SLLEVVVLSR NSRDAIAALG LLQKAVEGLL DATSGADADL
1690 1700 1710 1720 1730 1740
LLRYRECHLL VLKALQDGRA YGSPWCNKQI TRCLIECRDE YKYNVEAVEL LIRNHLVNMQ
1750 1760 1770 1780 1790 1800
QYDLHLAQSM ENGLNYMAVA FAMQLVKILL VDERSVAHVT EADLFHTIET LMRINAHSRG
1810 1820 1830 1840 1850 1860
NAPEGLPQLM EVVRSNYEAM IDRAHGGPNF MMHSGISQAS EYDDPPGLRE KAEYLLREWV
1870 1880 1890 1900 1910 1920
NLYHSAAAGR DSTKAFSAFV GQMHQQGILK TDDLITRFFR LCTEMCVEIS YRAQAEQQHN
1930 1940 1950 1960 1970 1980
PAANPTMIRA KCYHNLDAFV RLIALLVKHS GEATNTVTKI NLLNKVLGIV VGVLLQDHDV
1990 2000 2010 2020 2030 2040
RQSEFQQLPY HRIFIMLLLE LNAPEHVLET INFQTLTAFC NTFHILRPTK APGFVYAWLE
2050 2060 2070 2080 2090 2100
LISHRIFIAR MLAHTPQQKG WPMYAQLLID LFKYLAPFLR NVELTKPMQI LYKGTLRVLL
2110 2120 2130 2140 2150 2160
VLLHDFPEFL CDYHYGFCDV IPPNCIQLRN LILSAFPRNM RLPDPFTPNL KVDMLSEINI
2170 2180 2190 2200 2210 2220
APRILTNFTG VMPPQFKKDL DSYLKTRSPV TFLSDLRSNL QVSNEPGNRY NLQLINALVL
2230 2240 2250 2260 2270 2280
YVGTQAIAHI HNKGSTPSMS TITHSAHMDI FQNLAVDLDT EGRYLFLNAI ANQLRYPNSH
2290 2300 2310 2320 2330 2340
THYFSCTMLY LFAEANTEAI QEQITRVLLE RLIVNRPHPW GLLITFIELI KNPAFKFWNH
2350 2360 2370
EFVHCAPEIE KLFQSVAQCC MGQKQAQQVM EGTGAS
10 20 30 40 50 60
MNLDSLSLAL SQISYLVDNL TKKNYRASQQ EIQHIVNRHG PEADRHLLRC LFSHVDFSGD
70 80 90 100 110 120
GKSSGKDFHQ TQFLIQECAL LITKPNFIST LSYAIDNPLH YQKSLKPAPH LFAQLSKVLK
130 140 150 160 170 180
LSKVQEVIFG LALLNSSSSD LRGFAAQFIK QKLPDLLRSY IDADVSGNQE GGFQDIAIEV
190 200 210 220 230 240
LHLLLSHLLF GQKGAFGVGQ EQIDAFLKTL RRDFPQERCP VVLAPLLYPE KRDILMDRIL
250 260 270 280 290 300
PDSGGVAKTM MESSLADFMQ EVGYGFCASI EECRNIIVQF GVREVTAAQV ARVLGMMART
310 320 330 340 350 360
HSGLTDGIPL QSISAPGSGI WSDGKDKSDG AQAHTWNVEV LIDVLKELNP SLNFKEVTYE
370 380 390 400 410 420
LDHPGFQIRD SKGLHNVVYG IQRGLGMEVF PVDLIYRPWK HAEGQLSFIQ HSLINPEIFC
430 440 450 460 470 480
FADYPCHTVA TDILKAPPED DNREIATWKS LDLIESLLRL AEVGQYEQVK QLFSFPIKHC
490 500 510 520 530 540
PDMLVLALLQ INTSWHTLRH ELISTLMPIF LGNHPNSAII LHYAWHGQGQ SPSIRQLIMH
550 560 570 580 590 600
AMAEWYMRGE QYDQAKLSRI LDVAQDLKAL SMLLNGTPFA FVIDLAALAS RREYLKLDKW
610 620 630 640 650 660
LTDKIREHGE PFIQACMTFL KRRCPSILGG LAPEKDQPKS AQLPPETLAT MLACLQACAG
670 680 690 700 710 720
SVSQELSETI LTMVANCSNV MNKARQPPPG VMPKGRPPSA SSLDAISPVQ IDPLAGMTSL
730 740 750 760 770 780
SIGGSAAPHT QSMQGFPPNL GSAFSTPQSP AKAFPPLSTP NQTTAFSGIG GLSSQLPVGG
790 800 810 820 830 840
LGTGSLTGIG TGALGLPAVN NDPFVQRKLG TSGLNQPTFQ QSKMKPSDLS QVWPEANQHF
850 860 870 880 890 900
SKEIDDEANS YFQRIYNHPP HPTMSVDEVL EMLQRFKDST IKREREVFNC MLRNLFEEYR
910 920 930 940 950 960
FFPQYPDKEL HITACLFGGI IEKGLVTYMA LGLALRYVLE ALRKPFGSKM YYFGIAALDR
970 980 990 1000 1010 1020
FKNRLKDYPQ YCQHLASISH FMQFPHHLQE YIEYGQQSRD PPVKMQGSIT TPGSIALAQA
1030 1040 1050 1060 1070 1080
QAQAQVPAKA PLAGQVSTMV TTSTTTTVAK TVTVTRPTGV SFKKDVPPSI NTTNIDTLLV
1090 1100 1110 1120 1130 1140
ATDQTERIVE PPENIQEKIA FIFNNLSQSN MTQKVEELKE TVKEEFMPWV SQYLVMKRVS
1150 1160 1170 1180 1190 1200
IEPNFHSLYS NFLDTLKNPE FNKMVLNETY RNIKVLLTSD KAAANFSDRS LLKNLGHWLG
1210 1220 1230 1240 1250 1260
MITLAKNKPI LHTDLDVKSL LLEAYVKGQQ ELLYVVPFVA KVLESSIRSV VFRPPNPWTM
1270 1280 1290 1300 1310 1320
AIMNVLAELH QEHDLKLNLK FEIEVLCKNL ALDINELKPG NLLKDKDRLK NLDEQLSAPK
1330 1340 1350 1360 1370 1380
KDVKQPEELP PITTTTTSTT PATNTTCTAT VPPQPQYSYH DINVYSLAGL APHITLNPTI
1390 1400 1410 1420 1430 1440
PLFQAHPQLK QCVRQAIERA VQELVHPVVD RSIKIAMTTC EQIVRKDFAL DSEESRMRIA
1450 1460 1470 1480 1490 1500
AHHMMRNLTA GMAMITCREP LLMSISTNLK NSFASALRTA SPQQREMMDQ AAAQLAQDNC
1510 1520 1530 1540 1550 1560
ELACCFIQKT AVEKAGPEMD KRLATEFELR KHARQEGRRY CDPVVLTYQA ERMPEQIRLK
1570 1580 1590 1600 1610 1620
VGGVDPKQLA VYEEFARNVP GFLPTNDLSQ PTGFLAQPMK QAWATDDVAQ IYDKCITELE
1630 1640 1650 1660 1670 1680
QHLHAIPPTL AMNPQAQALR SLLEVVVLSR NSRDAIAALG LLQKAVEGLL DATSGADADL
1690 1700 1710 1720 1730 1740
LLRYRECHLL VLKALQDGRA YGSPWCNKQI TRCLIECRDE YKYNVEAVEL LIRNHLVNMQ
1750 1760 1770 1780 1790 1800
QYDLHLAQSM ENGLNYMAVA FAMQLVKILL VDERSVAHVT EADLFHTIET LMRINAHSRG
1810 1820 1830 1840 1850 1860
NAPEGLPQLM EVVRSNYEAM IDRAHGGPNF MMHSGISQAS EYDDPPGLRE KAEYLLREWV
1870 1880 1890 1900 1910 1920
NLYHSAAAGR DSTKAFSAFV GQMHQQGILK TDDLITRFFR LCTEMCVEIS YRAQAEQQHN
1930 1940 1950 1960 1970 1980
PAANPTMIRA KCYHNLDAFV RLIALLVKHS GEATNTVTKI NLLNKVLGIV VGVLLQDHDV
1990 2000 2010 2020 2030 2040
RQSEFQQLPY HRIFIMLLLE LNAPEHVLET INFQTLTAFC NTFHILRPTK APGFVYAWLE
2050 2060 2070 2080 2090 2100
LISHRIFIAR MLAHTPQQKG WPMYAQLLID LFKYLAPFLR NVELTKPMQI LYKGTLRVLL
2110 2120 2130 2140 2150 2160
VLLHDFPEFL CDYHYGFCDV IPPNCIQLRN LILSAFPRNM RLPDPFTPNL KVDMLSEINI
2170 2180 2190 2200 2210 2220
APRILTNFTG VMPPQFKKDL DSYLKTRSPV TFLSDLRSNL QVSNEPGNRY NLQLINALVL
2230 2240 2250 2260 2270 2280
YVGTQAIAHI HNKGSTPSMS TITHSAHMDI FQNLAVDLDT EGRYLFLNAI ANQLRYPNSH
2290 2300 2310 2320 2330 2340
THYFSCTMLY LFAEANTEAI QEQITRVLLE RLIVNRPHPW GLLITFIELI KNPAFKFWNH
2350 2360 2370
EFVHCAPEIE KLFQSVAQCC MGQKQAQQVM EGTGAS
Protein Neighborhood
Domains & Features
4 N-termini - 4 C-termini - 4 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
A5YKK6-1-unknown | MNLDSL... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
A5YKK6-1-unknown | MNLDSL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt71165 | |||
A5YKK6-1-unknown | MNLDSL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt71166 | |||
A5YKK6-1-unknown | MNLDSL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt71167 | |||
A5YKK6-630-unknown | GLAPEK... | 630 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6970 | |||
A5YKK6-630-unknown | GLAPEK... | 630 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5072 | |||
A5YKK6-630-unknown | GLAPEK... | 630 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt155046 | |||
A5YKK6-630-unknown | GLAPEK... | 630 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt155047 | |||
A5YKK6-630-unknown | GLAPEK... | 630 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt155048 | |||
A5YKK6-1672-unknown | ATSGAD... | 1672 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5076 | |||
A5YKK6-1672-unknown | ATSGAD... | 1672 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158401 | |||
A5YKK6-1672-unknown | ATSGAD... | 1672 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158402 | |||
A5YKK6-1879-unknown | FVGQMH... | 1879 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC3239 | |||
A5YKK6-1879-unknown | FVGQMH... | 1879 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158645 | |||
A5YKK6-1879-unknown | FVGQMH... | 1879 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt158646 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...PSILGG | 629 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC6970 | |||
...PSILGG | 629 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5072 | |||
...PSILGG | 629 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt138473 | |||
...PSILGG | 629 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt138474 | |||
...PSILGG | 629 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt138475 | |||
...EGLLDA | 1671 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC5076 | |||
...EGLLDA | 1671 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141898 | |||
...EGLLDA | 1671 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt141899 | |||
...KAFSAF | 1878 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC3239 | |||
...KAFSAF | 1878 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142149 | |||
...KAFSAF | 1878 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt142150 | |||
...GTGAS | 2376 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...GTGAS | 2376 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt66783 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATS_HUMAN | 629 | ILGG.|.GLAP | inferred from experiment | unknown | MEROPS | Schilling O | Biniossek ML et al.:Proteomic identification of pro... (C01.060) | 21967108, |
CATL1_HUMAN | 629 | ILGG.|.GLAP | inferred from experiment | unknown | MEROPS | Schilling O | Biniossek ML et al.:Proteomic identification of pro... (C01.060) | 21967108, |
CATL1_HUMAN | 1671 | LLDA.|.ATSG | inferred from experiment | unknown | MEROPS | Schilling O | Biniossek ML et al.:Proteomic identification of pro... (C01.060) | 21967108, |
CATB_HUMAN | 1878 | FSAF.|.FVGQ | inferred from experiment | unknown | MEROPS | Schilling O | Biniossek ML et al.:Proteomic identification of pro... (C01.060) | 21967108, |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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