TopFIND 4.0

P25774: Cathepsin S

General Information

Protein names
- Cathepsin S
- 3.4.22.27
Gene names CTSS
Organism Homo sapiens
Protease Family C01.034
Protease ID C01.034
Chromosome location
UniProt ID P25774

5

N-termini

3

C-termini

2

Cleavages

1199

Substrates

Sequence

        10         20         30         40         50         60 
MKRLVCVLLV CSSAVAQLHK DPTLDHHWHL WKKTYGKQYK EKNEEAVRRL IWEKNLKFVM 
        70         80         90        100        110        120 
LHNLEHSMGM HSYDLGMNHL GDMTSEEVMS LMSSLRVPSQ WQRNITYKSN PNRILPDSVD 
       130        140        150        160        170        180 
WREKGCVTEV KYQGSCGACW AFSAVGALEA QLKLKTGKLV SLSAQNLVDC STEKYGNKGC 
       190        200        210        220        230        240 
NGGFMTTAFQ YIIDNKGIDS DASYPYKAMD QKCQYDSKYR AATCSKYTEL PYGREDVLKE 
       250        260        270        280        290        300 
AVANKGPVSV GVDARHPSFF LYRSGVYYEP SCTQNVNHGV LVVGYGDLNG KEYWLVKNSW 
       310        320        330    
GHNFGEEGYI RMARNKGNHC GIASFPSYPE I

Isoforms

- Isoform 2 of Cathepsin S

Sequence View

        10         20         30         40         50         60 
MKRLVCVLLV CSSAVAQLHK DPTLDHHWHL WKKTYGKQYK EKNEEAVRRL IWEKNLKFVM 
        70         80         90        100        110        120 
LHNLEHSMGM HSYDLGMNHL GDMTSEEVMS LMSSLRVPSQ WQRNITYKSN PNRILPDSVD 
       130        140        150        160        170        180 
WREKGCVTEV KYQGSCGACW AFSAVGALEA QLKLKTGKLV SLSAQNLVDC STEKYGNKGC 
       190        200        210        220        230        240 
NGGFMTTAFQ YIIDNKGIDS DASYPYKAMD QKCQYDSKYR AATCSKYTEL PYGREDVLKE 
       250        260        270        280        290        300 
AVANKGPVSV GVDARHPSFF LYRSGVYYEP SCTQNVNHGV LVVGYGDLNG KEYWLVKNSW 
       310        320        330    
GHNFGEEGYI RMARNKGNHC GIASFPSYPE I



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Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 2 Cleavages - 1199 Substrates

N-termini

C-termini

Cleavages

Substrates