O00193: Small acidic protein

General Information

Protein names	- Small acidic protein
Gene names	SMAP
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O00193

7 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSAARESHPH GVKRSASPDD DLGSSNWEAA DLGNEERKQK FLRLMGAGKK EHTGRLVIGD
        70         80         90        100        110        120
HKSTSHFRTG EEDKKINEEL ESQYQQSMDS KLSGRYRRHC GLGFSEVEDH DGEGDVAGDD
       130        140        150        160        170        180
DDDDDDSPDP ESPDDSESDS ESEKEESAEE LQAAEHPDEV EDPKNKKDAK SNYKMMFVKS

SGS

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

7 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O00193-1-unknown	MSAARE...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O00193-15-	SASPDD...	15		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
O00193-15-	SASPDD...	15		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
O00193-15-	SASPDD...	15		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
O00193-24-unknown	SSNWEA...	24	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC6981
O00193-45-unknown	MGAGKK...	45	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000406221
O00193-171-	SNYKMM...	171		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
O00193-175-unknown	MMFVKS...	175		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
O00193-175-	MMFVKS...	175		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
O00193-175-	MMFVKS...	175		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
O00193-175-	MMFVKS...	175		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DDDLGS	23	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC6981
...GDVAGD	118	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000432207
...KSSGS	183	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	23	DLGS.\|.SSNW	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)