Q9Y266: Nuclear migration protein nudC

General Information

Protein names	- Nuclear migration protein nudC - Nuclear distribution protein C homolog
Gene names	NUDC
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9Y266

11 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGGEQEEERF DGMLLAMAQQ HEGGVQELVN TFFSFLRRKT DFFIGGEEGM AEKLITQTFS
        70         80         90        100        110        120
HHNQLAQKTR REKRARQEAE RREKAERAAR LAKEAKSETS GPQIKELTDE EAERLQLEID
       130        140        150        160        170        180
QKKDAENHEA QLKNGSLDSP GKQDTEEDEE EDEKDKGKLK PNLGNGADLP NYRWTQTLSE
       190        200        210        220        230        240
LDLAVPFCVN FRLKGKDMVV DIQRRHLRVG LKGQPAIIDG ELYNEVKVEE SSWLIEDGKV
       250        260        270        280        290        300
VTVHLEKINK MEWWSRLVSS DPEINTKKIN PENSKLSDLD SETRSMVEKM MYDQRQKSMG
       310        320        330
LPTSDEQKKQ EILKKFMDQH PEMDFSKAKF N

Isoforms

Sequence View

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Directness:

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Evidence Codes:

Methodology:

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Protease Assignment Confidence:

Evidence Names:

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Lab:

Protein Neighborhood

Domains & Features

11 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9Y266-1-	MGGEQE...	1		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9Y266-1-unknown	MGGEQE...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9Y266-1-unknown	MGGEQE...	1		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9Y266-2-	GGEQEE...	2		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q9Y266-2-	GGEQEE...	2		Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q9Y266-2-unknown	GGEQEE...	2		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9Y266-50-unknown	MAEKLI...	50	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000400981
Q9Y266-94-	EAKSET...	94		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9Y266-139-unknown	SPGKQD...	139	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8154
Q9Y266-148-unknown	DEEEDE...	148	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19873
Q9Y266-315-unknown	KFMDQH...	315		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
Q9Y266-315-	KFMDQH...	315		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9Y266-316-	FMDQHP...	316		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q9Y266-316-	FMDQHP...	316		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...NGSLDS	138	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8154
...QDTEED	147	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19873
...LSELDL	182	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000404020
...LSELDL	182	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000400981
...KAKFN	331	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CATS_HUMAN	138	SLDS.\|.SPGK	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
MEP1B_HUMAN	147	TEED.\|.DEEE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)