TopFIND 4.0

P10809: 60 kDa heat shock protein, mitochondrial

General Information

Protein names
- 60 kDa heat shock protein, mitochondrial
- 5.6.1.7 {ECO:0000305}
- 60 kDa chaperonin
- Chaperonin 60
- CPN60
- Heat shock protein 60
- HSP-60
- Hsp60
- HuCHA60
- Mitochondrial matrix protein P1
- P60 lymphocyte protein

Gene names HSPD1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P10809

50

N-termini

30

C-termini

33

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLRLPTVFRQ MRPVSRVLAP HLTRAYAKDV KFGADARALM LQGVDLLADA VAVTMGPKGR 
        70         80         90        100        110        120 
TVIIEQSWGS PKVTKDGVTV AKSIDLKDKY KNIGAKLVQD VANNTNEEAG DGTTTATVLA 
       130        140        150        160        170        180 
RSIAKEGFEK ISKGANPVEI RRGVMLAVDA VIAELKKQSK PVTTPEEIAQ VATISANGDK 
       190        200        210        220        230        240 
EIGNIISDAM KKVGRKGVIT VKDGKTLNDE LEIIEGMKFD RGYISPYFIN TSKGQKCEFQ 
       250        260        270        280        290        300 
DAYVLLSEKK ISSIQSIVPA LEIANAHRKP LVIIAEDVDG EALSTLVLNR LKVGLQVVAV 
       310        320        330        340        350        360 
KAPGFGDNRK NQLKDMAIAT GGAVFGEEGL TLNLEDVQPH DLGKVGEVIV TKDDAMLLKG 
       370        380        390        400        410        420 
KGDKAQIEKR IQEIIEQLDV TTSEYEKEKL NERLAKLSDG VAVLKVGGTS DVEVNEKKDR 
       430        440        450        460        470        480 
VTDALNATRA AVEEGIVLGG GCALLRCIPA LDSLTPANED QKIGIEIIKR TLKIPAMTIA 
       490        500        510        520        530        540 
KNAGVEGSLI VEKIMQSSSE VGYDAMAGDF VNMVEKGIID PTKVVRTALL DAAGVASLLT 
       550        560        570    
TAEVVVTEIP KEEKDPGMGA MGGMGGGMGG GMF

Isoforms

- Isoform 2 of 60 kDa heat shock protein, mitochondrial

Sequence View

        10         20         30         40         50         60 
MLRLPTVFRQ MRPVSRVLAP HLTRAYAKDV KFGADARALM LQGVDLLADA VAVTMGPKGR 
        70         80         90        100        110        120 
TVIIEQSWGS PKVTKDGVTV AKSIDLKDKY KNIGAKLVQD VANNTNEEAG DGTTTATVLA 
       130        140        150        160        170        180 
RSIAKEGFEK ISKGANPVEI RRGVMLAVDA VIAELKKQSK PVTTPEEIAQ VATISANGDK 
       190        200        210        220        230        240 
EIGNIISDAM KKVGRKGVIT VKDGKTLNDE LEIIEGMKFD RGYISPYFIN TSKGQKCEFQ 
       250        260        270        280        290        300 
DAYVLLSEKK ISSIQSIVPA LEIANAHRKP LVIIAEDVDG EALSTLVLNR LKVGLQVVAV 
       310        320        330        340        350        360 
KAPGFGDNRK NQLKDMAIAT GGAVFGEEGL TLNLEDVQPH DLGKVGEVIV TKDDAMLLKG 
       370        380        390        400        410        420 
KGDKAQIEKR IQEIIEQLDV TTSEYEKEKL NERLAKLSDG VAVLKVGGTS DVEVNEKKDR 
       430        440        450        460        470        480 
VTDALNATRA AVEEGIVLGG GCALLRCIPA LDSLTPANED QKIGIEIIKR TLKIPAMTIA 
       490        500        510        520        530        540 
KNAGVEGSLI VEKIMQSSSE VGYDAMAGDF VNMVEKGIID PTKVVRTALL DAAGVASLLT 
       550        560        570    
TAEVVVTEIP KEEKDPGMGA MGGMGGGMGG GMF



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(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

50 N-termini - 30 C-termini - 33 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)