TopFIND 4.0

Q16819: Meprin A subunit alpha

General Information

Protein names
- Meprin A subunit alpha
- 3.4.24.18
- Endopeptidase-2
- N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha
- PABA peptide hydrolase
- PPH alpha
Gene names MEP1A
Organism Homo sapiens
Protease Family M12.002
Protease ID M12.002
Chromosome location
UniProt ID Q16819

8

N-termini

8

C-termini

17

Cleavages

1341

Substrates

Sequence

        10         20         30         40         50         60 
MAWIRSTCIL FFTLLFAHIA AVPIKYLPEE NVHDADFGEQ KDISEINLAA GLDLFQGDIL 
        70         80         90        100        110        120 
LQKSRNGLRD PNTRWTFPIP YILADNLGLN AKGAILYAFE MFRLKSCVDF KPYEGESSYI 
       130        140        150        160        170        180 
IFQQFDGCWS EVGDQHVGQN ISIGQGCAYK AIIEHEILHA LGFYHEQSRT DRDDYVNIWW 
       190        200        210        220        230        240 
DQILSGYQHN FDTYDDSLIT DLNTPYDYES LMHYQPFSFN KNASVPTITA KIPEFNSIIG 
       250        260        270        280        290        300 
QRLDFSAIDL ERLNRMYNCT TTHTLLDHCT FEKANICGMI QGTRDDTDWA HQDSAQAGEV 
       310        320        330        340        350        360 
DHTLLGQCTG AGYFMQFSTS SGSAEEAALL ESRILYPKRK QQCLQFFYKM TGSPSDRLVV 
       370        380        390        400        410        420 
WVRRDDSTGN VRKLVKVQTF QGDDDHNWKI AHVVLKEEQK FRYLFQGTKG DPQNSTGGIY 
       430        440        450        460        470        480 
LDDITLTETP CPTGVWTVRN FSQVLENTSK GDKLQSPRFY NSEGYGFGVT LYPNSRESSG 
       490        500        510        520        530        540 
YLRLAFHVCS GENDAILEWP VENRQVIITI LDQEPDVRNR MSSSMVFTTS KSHTSPAIND 
       550        560        570        580        590        600 
TVIWDRPSRV GTYHTDCNCF RSIDLGWSGF ISHQMLKRRS FLKNDDLIIF VDFEDITHLS 
       610        620        630        640        650        660 
QTEVPTKGKR LSPQGLILQG QEQQVSEEGS GKAMLEEALP VSLSQGQPSR QKRSVENTGP 
       670        680        690        700        710        720 
LEDHNWPQYF RDPCDPNPCQ NDGICVNVKG MASCRCISGH AFFYTGERCQ AVQVHGSVLG 
       730        740    
MVIGGTAGVI FLTFSIIAIL SQRPRK

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

8 N-termini - 8 C-termini - 17 Cleavages - 1341 Substrates

N-termini

C-termini

Cleavages

Substrates