TopFIND 4.0

P52788: Spermine synthase

General Information

Protein names
- Spermine synthase
- SPMSY
- 2.5.1.22
- Spermidine aminopropyltransferase
Gene names SMS
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P52788

4

N-termini

2

C-termini

2

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAAARHSTLD FMLGAKADGE TILKGLQSIF QEQGMAESVH TWQDHGYLAT YTNKNGSFAN 
        70         80         90        100        110        120 
LRIYPHGLVL LDLQSYDGDA QGKEEIDSIL NKVEERMKEL SQDSTGRVKR LPPIVRGGAI 
       130        140        150        160        170        180 
DRYWPTADGR LVEYDIDEVV YDEDSPYQNI KILHSKQFGN ILILSGDVNL AESDLAYTRA 
       190        200        210        220        230        240 
IMGSGKEDYT GKDVLILGGG DGGILCEIVK LKPKMVTMVE IDQMVIDGCK KYMRKTCGDV 
       250        260        270        280        290        300 
LDNLKGDCYQ VLIEDCIPVL KRYAKEGREF DYVINDLTAV PISTSPEEDS TWEFLRLILD 
       310        320        330        340        350        360 
LSMKVLKQDG KYFTQGNCVN LTEALSLYEE QLGRLYCPVE FSKEIVCVPS YLELWVFYTV 
   
WKKAKP

Isoforms

- Isoform 2 of Spermine synthase

Sequence View

        10         20         30         40         50         60 
MAAARHSTLD FMLGAKADGE TILKGLQSIF QEQGMAESVH TWQDHGYLAT YTNKNGSFAN 
        70         80         90        100        110        120 
LRIYPHGLVL LDLQSYDGDA QGKEEIDSIL NKVEERMKEL SQDSTGRVKR LPPIVRGGAI 
       130        140        150        160        170        180 
DRYWPTADGR LVEYDIDEVV YDEDSPYQNI KILHSKQFGN ILILSGDVNL AESDLAYTRA 
       190        200        210        220        230        240 
IMGSGKEDYT GKDVLILGGG DGGILCEIVK LKPKMVTMVE IDQMVIDGCK KYMRKTCGDV 
       250        260        270        280        290        300 
LDNLKGDCYQ VLIEDCIPVL KRYAKEGREF DYVINDLTAV PISTSPEEDS TWEFLRLILD 
       310        320        330        340        350        360 
LSMKVLKQDG KYFTQGNCVN LTEALSLYEE QLGRLYCPVE FSKEIVCVPS YLELWVFYTV 
   
WKKAKP



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 2 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)