P03956: Interstitial collagenase

General Information

Protein names	- Interstitial collagenase - 3.4.24.7 {ECO:0000269\|PubMed:1645757, ECO:0000269\|PubMed:16807369, ECO:0000269\|PubMed:2153297, ECO:0000269\|PubMed:2557822} - Fibroblast collagenase - Matrix metalloproteinase-1 - MMP-1 - 22 kDa interstitial collagenase - 27 kDa interstitial collagenase
Gene names	MMP1
Organism	Homo sapiens
Protease Family	M10.001
Protease ID	M10.001
Chromosome location
UniProt ID	P03956

12 N-termini

13 C-termini

20 Cleavages

108 Substrates

Sequence

        10         20         30         40         50         60
MHSFPPLLLL LFWGVVSHSF PATLETQEQD VDLVQKYLEK YYNLKNDGRQ VEKRRNSGPV
        70         80         90        100        110        120
VEKLKQMQEF FGLKVTGKPD AETLKVMKQP RCGVPDVAQF VLTEGNPRWE QTHLTYRIEN
       130        140        150        160        170        180
YTPDLPRADV DHAIEKAFQL WSNVTPLTFT KVSEGQADIM ISFVRGDHRD NSPFDGPGGN
       190        200        210        220        230        240
LAHAFQPGPG IGGDAHFDED ERWTNNFREY NLHRVAAHEL GHSLGLSHST DIGALMYPSY
       250        260        270        280        290        300
TFSGDVQLAQ DDIDGIQAIY GRSQNPVQPI GPQTPKACDS KLTFDAITTI RGEVMFFKDR
       310        320        330        340        350        360
FYMRTNPFYP EVELNFISVF WPQLPNGLEA AYEFADRDEV RFFKGNKYWA VQGQNVLHGY
       370        380        390        400        410        420
PKDIYSSFGF PRTVKHIDAA LSEENTGKTY FFVANKYWRY DEYKRSMDPG YPKMIAHDFP
       430        440        450        460
GIGHKVDAVF MKDGFFYFFH GTRQYKFDPK TKRILTLQKA NSWFNCRKN

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

12 N-termini - 13 C-termini - 20 Cleavages - 108 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P03956-26-unknown	TQEQDV...	26	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17077
P03956-28-unknown	EQDVDL...	28	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18418
P03956-55-unknown	RNSGPV...	55	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16697
P03956-84-unknown	LKVMKQ...	84	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21728
P03956-87-unknown	MKQPRC...	87	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21729
P03956-92-unknown	CGVPDV...	92	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26975
P03956-92-unknown	CGVPDV...	92	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27271
P03956-92-unknown	CGVPDV...	92	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26564
P03956-92-unknown	CGVPDV...	92	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26830
P03956-92-unknown	CGVPDV...	92	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27122
P03956-100-unknown	FVLTEG...	100	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P03956-100-unknown	FVLTEG...	100	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27475
P03956-100-unknown	FVLTEG...	100	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23998
P03956-100-unknown	FVLTEG...	100	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21730
P03956-100-unknown	FVLTEG...	100	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23798
P03956-101-unknown	VLTEGN...	101	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21731
P03956-102-unknown	LTEGNP...	102	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21732
P03956-103-unknown	TEGNPR...	103	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8411
P03956-185-unknown	FQPGPG...	185	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17078
P03956-185-unknown	FQPGPG...	185	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18419
P03956-270-unknown	IGPQTP...	270	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P03956-270-unknown	IGPQTP...	270	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21733

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PATLET	25	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17077
...TLETQE	27	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18418
...QVEKRR	54	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16697
...PDAETL	83	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21728
...ETLKVM	86	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21729
...MKQPRC	91	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26975
...MKQPRC	91	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27271
...MKQPRC	91	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26564
...MKQPRC	91	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26830
...MKQPRC	91	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27122
...PDVAQF	99	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27475
...PDVAQF	99	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23998
...PDVAQF	99	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21730
...PDVAQF	99	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23798
...DVAQFV	100	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21731
...VAQFVL	101	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21732
...AQFVLT	102	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8411
...NLAHAF	184	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17078
...NLAHAF	184	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC18419
...NPVQPI	269	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...NPVQPI	269	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21733
...NCRKN	469	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MEP1A_HUMAN	25	TLET.\|.TQEQ	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	27	ETQE.\|.EQDV	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
KLKB1_HUMAN	54	EKRR.\|.RNSG	inferred from experiment	unknown	MEROPS	Nagase H	Suzuki K et al.:Mechanisms of activation of tis... (S01.212)	2176865,
MMP1_HUMAN	83	AETL.\|.LKVM	inferred from experiment	unknown	MEROPS	Weiss SJ	Desrochers PE et al.:Interstitial collagenase (matri... (M10.001)	1645757,
MMP1_HUMAN	86	LKVM.\|.MKQP	inferred from experiment	unknown	MEROPS		Merops MMP1_HUMAN -> MMP1_HUMAN @86
PCSK5_HUMAN	91	QPRC.\|.CGVP	inferred from experiment	unknown	MEROPS	Strongin AY	Remacle AG et al.:Substrate cleavage analysis of ... (S08.071)	18505722,
PCSK7_HUMAN	91	QPRC.\|.CGVP	inferred from experiment	unknown	MEROPS	Strongin AY	Remacle AG et al.:Substrate cleavage analysis of ... (S08.071)	18505722,
NEC2_HUMAN	91	QPRC.\|.CGVP	inferred from experiment	unknown	MEROPS	Strongin AY	Remacle AG et al.:Substrate cleavage analysis of ... (S08.071)	18505722,
PCSK4_HUMAN	91	QPRC.\|.CGVP	inferred from experiment	unknown	MEROPS	Strongin AY	Remacle AG et al.:Substrate cleavage analysis of ... (S08.071)	18505722,
PCSK6_HUMAN	91	QPRC.\|.CGVP	inferred from experiment	unknown	MEROPS	Strongin AY	Remacle AG et al.:Substrate cleavage analysis of ... (S08.071)	18505722,
PLMN_HUMAN	99	VAQF.\|.FVLT	inferred from experiment	unknown	MEROPS		Merops PLMN_HUMAN -> MMP1_HUMAN @99
MMP7_HUMAN	99	VAQF.\|.FVLT	inferred from experiment	unknown	MEROPS	Woessner JF Jr	Abramson SR et al.:Characterization of rat uterine... (M10.008)	7608162,
MMP1_HUMAN	99	VAQF.\|.FVLT	inferred from experiment	unknown	MEROPS	Weiss SJ	Desrochers PE et al.:Interstitial collagenase (matri... (M10.001)	1645757,
MMP3_HUMAN	99	VAQF.\|.FVLT	inferred from experiment	unknown	MEROPS	Nagase H	Suzuki K et al.:Mechanisms of activation of tis... (S01.212)	2176865,
MMP1_HUMAN	100	AQFV.\|.VLTE	inferred from experiment	unknown	MEROPS	Weiss SJ	Desrochers PE et al.:Interstitial collagenase (matri... (M10.001)	1645757,
MMP1_HUMAN	101	QFVL.\|.LTEG	inferred from experiment	unknown	MEROPS	Weiss SJ	Desrochers PE et al.:Interstitial collagenase (matri... (M10.001)	1645757,
CMA1_HUMAN	102	FVLT.\|.TEGN	inferred from experiment	unknown	MEROPS	Caughey GH	Raymond WW et al.:Albumin is a substrate of human... (S01.140)	12815038,
MEP1A_HUMAN	184	AHAF.\|.FQPG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1B_HUMAN	184	AHAF.\|.FQPG	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MMP1_HUMAN	269	VQPI.\|.IGPQ	inferred from experiment	unknown	MEROPS	Weiss SJ	Desrochers PE et al.:Interstitial collagenase (matri... (M10.001)	1645757,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CCL8_HUMAN	4	KVSA.\|.AALL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
CCL7_HUMAN	4	KASA.\|.AALL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
CCL2_HUMAN	4	KVSA.\|.AALL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
CCL13_HUMAN	4	KVSA.\|.AVLL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
SYUA_HUMAN	7	MKGL.\|.LSKA	inferred from experiment	unknown	MEROPS	Lorenzl S	Levin J et al.:Increased alpha-synuclein aggre... (M10.001)	19022250,
CCL16_HUMAN	7	EAAL.\|.LSLL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
CCL23_HUMAN	10	LSCL.\|.LMLV		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
CCL4_HUMAN	15	LVAA.\|.AFCS		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
CCL23-Isoform2_HUMAN	16	VTAL.\|.LGSQ	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC34828
CCL23_HUMAN	16	VTAL.\|.LGSQ		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
SYUA-Isoform3_HUMAN	18	VAAA.\|.AEKT	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21766
SYUA-Isoform2_HUMAN	18	VAAA.\|.AEKT	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21766
SYUA_HUMAN	18	VAAA.\|.AEKT	inferred from experiment	unknown	MEROPS	Lorenzl S	Levin J et al.:Increased alpha-synuclein aggre... (M10.001)	19022250,
SYUA-Isoform3_HUMAN	21	AEKT.\|.TKQG	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21769
SYUA-Isoform2_HUMAN	21	AEKT.\|.TKQG	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21769
SYUA_HUMAN	21	AEKT.\|.TKQG	inferred from experiment	unknown	MEROPS	Lorenzl S	Levin J et al.:Increased alpha-synuclein aggre... (M10.001)	19022250,
CCL23-Isoform2_HUMAN	22	QARV.\|.VTKD	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC34830
CCL23_HUMAN	22	QARV.\|.VTKD		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
CCL15_HUMAN	24	QFIN.\|.NDAE		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
CCL23-Isoform2_HUMAN	25	VTKD.\|.DAET	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC34832
CCL23_HUMAN	25	VTKD.\|.DAET		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
CCL13_HUMAN	26	QPDA.\|.ALNV	inferred from experiment	unknown	MEROPS	Overall CM	McQuibban GA et al.:Matrix metalloproteinase proces... (M10.013)	12149192,
CCL23-Isoform2_HUMAN	27	KDAE.\|.ETEF	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC34834
CCL2_HUMAN	27	PDAI.\|.INAP	inferred from experiment	unknown	MEROPS	Overall CM	McQuibban GA et al.:Matrix metalloproteinase proces... (M10.013)	12149192,
CCL7_HUMAN	27	PVGI.\|.INTS	inferred from experiment	unknown	MEROPS	Overall CM	McQuibban GA et al.:Matrix metalloproteinase proces... (M10.013)	12149192,
CCL13_HUMAN	27	PDAL.\|.LNVP	inferred from experiment	unknown	MEROPS	Overall CM	McQuibban GA et al.:Matrix metalloproteinase proces... (M10.013)	12149192,
CCL23_HUMAN	27	KDAE.\|.ETEF		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
IL8-Isoform2_HUMAN	28	PRSA.\|.AKEL	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21738
IL8_HUMAN	28	PRSA.\|.AKEL	inferred from experiment	unknown	MEROPS	Overall CM	Tester AM et al.:LPS responsiveness and neutroph... (M10.013)	17375198,
CCL23-Isoform2_HUMAN	29	AETE.\|.EFMM	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC34836
CCL23_HUMAN	29	AETE.\|.EFMM		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
CCL13_HUMAN	30	LNVP.\|.PSTC	inferred from experiment	unknown	MEROPS	Overall CM	McQuibban GA et al.:Matrix metalloproteinase proces... (M10.013)	12149192,
HPLN1_HUMAN	31	AIHI.\|.IQAE	inferred from experiment	unknown	MEROPS	Roughley PJ	Nguyen Q et al.:Matrix metalloproteinases cleav... (M10.006)	7694569,
SYUA-Isoform2_HUMAN	41	YVGS.\|.SKTK	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21772
SAA1_HUMAN	41	YSDM.\|.MREA	inferred from experiment	unknown	MEROPS	Simon A	van der Hilst JC et al.:Increased susceptibility of ser... (M10.001)	18815155,
PAR1_HUMAN	41	DPRS.\|.SFLL	inferred from experiment	unknown	MEROPS	Kuliopulos A	Boire A et al.:PAR1 is a matrix metalloproteas... (M10.001)	15707890,
SYUA_HUMAN	41	YVGS.\|.SKTK	inferred from experiment	unknown	MEROPS	Lorenzl S	Levin J et al.:Increased alpha-synuclein aggre... (M10.001)	19022250,
CXCL5_HUMAN	45	VLRE.\|.ELRC	inferred from experiment	unknown	MEROPS	Overall CM	Tester AM et al.:LPS responsiveness and neutroph... (M10.013)	17375198,
SYUA-Isoform2_HUMAN	47	KEGV.\|.VVHG	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21774
SAA1_HUMAN	47	ANYI.\|.IGSD	inferred from experiment	unknown	MEROPS	Simon A	van der Hilst JC et al.:Increased susceptibility of ser... (M10.001)	18815155,
SYUA_HUMAN	47	KEGV.\|.VVHG	inferred from experiment	unknown	MEROPS	Lorenzl S	Levin J et al.:Increased alpha-synuclein aggre... (M10.001)	19022250,
CCL3_HUMAN	47	NFIA.\|.ADYF		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
TFPI1_HUMAN	48	PLKL.\|.LMHS	inferred from experiment	unknown	MEROPS	Shapiro SD	Belaaouaj AA et al.:Matrix metalloproteinases cleav... (M10.009)	10859319,
TFPI1-Isoform2_HUMAN	48	PLKL.\|.LMHS	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21740
SYUA-Isoform3_HUMAN	56	GAVV.\|.VTGV	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21776
SYUA-Isoform3_HUMAN	57	AVVT.\|.TGVT	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21779
MMP9_HUMAN	59	VAEM.\|.MRGE	inferred from experiment	unknown	MEROPS	Van Wart HE	Sang QX et al.:Proteolytic and non-proteolytic... (M10.001)	7669817,
CCL4_HUMAN	61	SQPA.\|.AVVF		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
SYUA-Isoform3_HUMAN	64	AVAQ.\|.QKTV	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21782
SYUA-Isoform2_HUMAN	70	GAVV.\|.VTGV	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21776
SYUA_HUMAN	70	GAVV.\|.VTGV	inferred from experiment	unknown	MEROPS	Lorenzl S	Levin J et al.:Increased alpha-synuclein aggre... (M10.001)	19022250,
SYUA-Isoform2_HUMAN	71	AVVT.\|.TGVT	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21779
SYUA_HUMAN	71	AVVT.\|.TGVT	inferred from experiment	unknown	MEROPS	Lorenzl S	Levin J et al.:Increased alpha-synuclein aggre... (M10.001)	19022250,
CCL13_HUMAN	72	GKEI.\|.ICAD		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
CCL8_HUMAN	73	GKEV.\|.VCAD		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
SAA2_HUMAN	75	AEVI.\|.ISNA	inferred from experiment	unknown	MEROPS	Rocken C	Stix B et al.:Proteolysis of AA amyloid fibri... (M10.001)	11485914,
SYUA-Isoform3_HUMAN	76	IAAA.\|.ATGF	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21785
SYUA-Isoform2_HUMAN	78	AVAQ.\|.QKTV	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21782
SYUA_HUMAN	78	AVAQ.\|.QKTV	inferred from experiment	unknown	MEROPS	Lorenzl S	Levin J et al.:Increased alpha-synuclein aggre... (M10.001)	19022250,
PRL_HUMAN	81	ITKA.\|.AINS	inferred from experiment	unknown	MEROPS	Clapp C	Macotela Y et al.:Matrix metalloproteases from ch... (M10.013)	16608881,
SYUA-Isoform3_HUMAN	83	VKKD.\|.DQLG	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21788
MMP1_HUMAN	83	AETL.\|.LKVM	inferred from experiment	unknown	MEROPS	Weiss SJ	Desrochers PE et al.:Interstitial collagenase (matri... (M10.001)	1645757,
CCL16_HUMAN	85	WVQE.\|.EYIK		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP1_HUMAN	86	LKVM.\|.MKQP	inferred from experiment	unknown	MEROPS		Merops MMP1_HUMAN -> MMP1_HUMAN @86
SYUA-Isoform2_HUMAN	90	IAAA.\|.ATGF	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21785
SYUA_HUMAN	90	IAAA.\|.ATGF	inferred from experiment	unknown	MEROPS	Lorenzl S	Levin J et al.:Increased alpha-synuclein aggre... (M10.001)	19022250,
MMP9_HUMAN	93	LKAM.\|.MRTP	inferred from experiment	unknown	MEROPS	Van Wart HE	Sang QX et al.:Proteolytic and non-proteolytic... (M10.001)	7669817,
SYUA_HUMAN	97	VKKD.\|.DQLG	inferred from experiment	unknown	MEROPS	Lorenzl S	Levin J et al.:Increased alpha-synuclein aggre... (M10.001)	19022250,
MMP1_HUMAN	99	VAQF.\|.FVLT	inferred from experiment	unknown	MEROPS	Weiss SJ	Desrochers PE et al.:Interstitial collagenase (matri... (M10.001)	1645757,
MMP1_HUMAN	100	AQFV.\|.VLTE	inferred from experiment	unknown	MEROPS	Weiss SJ	Desrochers PE et al.:Interstitial collagenase (matri... (M10.001)	1645757,
MMP1_HUMAN	101	QFVL.\|.LTEG	inferred from experiment	unknown	MEROPS	Weiss SJ	Desrochers PE et al.:Interstitial collagenase (matri... (M10.001)	1645757,
MMP9_HUMAN	106	LGRF.\|.FQTF	inferred from experiment	unknown	MEROPS	Van Wart HE	Sang QX et al.:Proteolytic and non-proteolytic... (M10.001)	7669817,
C1QA_HUMAN	108	PGNI.\|.IKDQ	inferred from experiment	unknown	MEROPS	Tenner AJ	Ruiz S et al.:Digestion of C1q collagen-like ... (M10.001)	10496311,
SYUA-Isoform3_HUMAN	119	EGYQ.\|.QDYE	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21790
SYUA-Isoform3_HUMAN	120	GYQD.\|.DYEP	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21792
IBP3-Isoform2_HUMAN	123	SRLR.\|.RAYL	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21753
IBP3_HUMAN	123	SRLR.\|.RAYL	inferred from experiment	unknown	MEROPS	Nagase H	Fowlkes JL et al.:Matrix metalloproteinases degra... (M10.001)	7523391,
IBP3_HUMAN	124	RLRA.\|.AYLL	inferred from experiment	unknown	MEROPS	Cohen P	Gibson TL et al.:Inflammation-related neutrophil... (S01.133)	10512690,
IBP3-Isoform2_HUMAN	124	RLRA.\|.AYLL	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21755
IBP3_HUMAN	126	RAYL.\|.LLPA	inferred from experiment	unknown	MEROPS	Nagase H	Fowlkes JL et al.:Matrix metalloproteinases degra... (M10.001)	7523391,
SYUA_HUMAN	133	EGYQ.\|.QDYE	inferred from experiment	unknown	MEROPS	Lorenzl S	Levin J et al.:Increased alpha-synuclein aggre... (M10.001)	19022250,
SYUA_HUMAN	134	GYQD.\|.DYEP	inferred from experiment	unknown	MEROPS	Lorenzl S	Levin J et al.:Increased alpha-synuclein aggre... (M10.001)	19022250,
PRL_HUMAN	139	PEAI.\|.ILSK	inferred from experiment	unknown	MEROPS	Clapp C	Macotela Y et al.:Matrix metalloproteases from ch... (M10.013)	16608881,
IBP3_HUMAN	168	HPLH.\|.HSKI	inferred from experiment	unknown	MEROPS	Nagase H	Fowlkes JL et al.:Matrix metalloproteinases degra... (M10.001)	7523391,
IBP3_HUMAN	169	PLHS.\|.SKII	inferred from experiment	unknown	MEROPS	Cohen P	Gibson TL et al.:Inflammation-related neutrophil... (M10.001)	10512690,
IBP3-Isoform2_HUMAN	174	HPLH.\|.HSKI	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21758
IBP3-Isoform2_HUMAN	175	PLHS.\|.SKII	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21760
PRL_HUMAN	184	PSLQ.\|.QMAD	inferred from experiment	unknown	MEROPS	Clapp C	Macotela Y et al.:Matrix metalloproteases from ch... (M10.013)	16608881,
CCN2_HUMAN	194	PTMI.\|.IRAN	inferred from experiment	unknown	MEROPS	Okada Y	Hashimoto G et al.:Matrix metalloproteinases cleav... (M10.013)	12114504,
CCN2_HUMAN	199	ANCL.\|.LVQT	inferred from experiment	unknown	MEROPS	Okada Y	Hashimoto G et al.:Matrix metalloproteinases cleav... (M10.013)	12114504,
MMP1_HUMAN	269	VQPI.\|.IGPQ	inferred from experiment	unknown	MEROPS	Weiss SJ	Desrochers PE et al.:Interstitial collagenase (matri... (M10.001)	1645757,
PGCA-Isoform3_HUMAN	360	PENF.\|.FFGV	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21747
PGCA-Isoform2_HUMAN	360	PENF.\|.FFGV	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21747
PGCA_HUMAN	360	PENF.\|.FFGV	inferred from experiment	unknown	MEROPS	Neame PJ	Fosang AJ et al.:Degradation of cartilage aggrec... (M10.013)	8603731,
A1AT_HUMAN	376	AMFL.\|.LEAI	inferred from experiment	unknown	MEROPS	Travis J	Nelson D et al.:Inactivation of alpha1-proteina... (M10.001)	9657883,
A1AT_HUMAN	381	AIPM.\|.MSIP	inferred from experiment	unknown	MEROPS	Weiss SJ	Desrochers PE et al.:Interstitial collagenase (matri... (M10.001)	1645757,
AACT_HUMAN	384	LLSA.\|.ALVE	inferred from experiment	unknown	MEROPS	Salvesen G	Mast AE et al.:Kinetics and physiologic releva... (M10.001)	1651920,
PGCA_HUMAN	460	SEDL.\|.LVVQ	inferred from experiment	unknown	MEROPS	Neame PJ	Fosang AJ et al.:Degradation of cartilage aggrec... (M10.013)	8603731,
PGCA-Isoform3_HUMAN	460	SEDL.\|.LVVQ	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21750
PGCA-Isoform2_HUMAN	460	SEDL.\|.LVVQ	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21750
A2MG_HUMAN	702	PEGL.\|.LRVG	inferred from experiment	unknown	MEROPS		Merops MMP1_HUMAN -> A2MG_HUMAN @702
CO2A1-Isoform1_HUMAN	837	RVGP.\|.PPGS	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21722
CO1A2_HUMAN	865	PQGL.\|.LLGA	inferred from experiment	unknown	MEROPS	Poole AR	Billinghurst RC et al.:Enhanced cleavage of type II co... (M10.013)	9119997,
CO2A1-Isoform1_HUMAN	906	PQGL.\|.LAGQ	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TC21724
CO2A1_HUMAN	906	RVGP.\|.PPGS	inferred from experiment	unknown	MEROPS	Hambor JE	Mitchell PG et al.:Cloning, expression, and type I... (M10.013)	8609233,
CO3A1_HUMAN	948	PLGI.\|.IAGI	inferred from experiment	unknown	MEROPS	Poole AR	Billinghurst RC et al.:Enhanced cleavage of type II co... (M10.013)	9119997,
CO1A1_HUMAN	953	PQGI.\|.IAGQ	inferred from experiment	unknown	MEROPS		Merops MMP1_HUMAN -> CO1A1_HUMAN @953
CO2A1_HUMAN	975	PQGL.\|.LAGQ	inferred from experiment	unknown	MEROPS	Poole AR	Billinghurst RC et al.:Enhanced cleavage of type II co... (M10.013)	9119997,