P0DJI9: Serum amyloid A-2 protein

General Information

Protein names	- Serum amyloid A-2 protein - SAA2
Gene names	SAA2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P0DJI9

5 N-termini

4 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MKLLTGLVFC SLVLSVSSRS FFSFLGEAFD GARDMWRAYS DMREANYIGS DKYFHARGNY
        70         80         90        100        110        120
DAAKRGPGGA WAAEVISNAR ENIQRLTGRG AEDSLADQAA NKWGRSGRDP NHFRPAGLPE

KY

Isoforms

- Isoform 2 of Serum amyloid A-2 protein

Sequence View

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Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P0DJI9-1-unknown	MKLLTG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt88819
P0DJI9-19-unknown	RSFFSF...	19	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P0DJI9-19-unknown	RSFFSF...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt112160
P0DJI9-70-unknown	AWAAEV...	70	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC22661
P0DJI9-75-unknown	VISNAR...	75	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23842
P0DJI9-76-unknown	ISNARE...	76	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23843
P0DJI9-76-unknown	ISNARE...	76	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21737

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RGPGGA	69	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC22661
...RGPGGA	69	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154021
...AWAAEV	74	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23842
...AWAAEV	74	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154078
...WAAEVI	75	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC23843
...WAAEVI	75	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21737
...WAAEVI	75	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt154080
...LPEKY	122	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP2_HUMAN	69	PGGA.\|.AWAA	inferred from experiment	unknown	MEROPS	Rocken C	Stix B et al.:Proteolysis of AA amyloid fibri... (M10.001)	11485914,
MMP3_HUMAN	74	AAEV.\|.VISN	inferred from experiment	unknown	MEROPS	Rocken C	Stix B et al.:Proteolysis of AA amyloid fibri... (M10.001)	11485914,
MMP3_HUMAN	75	AEVI.\|.ISNA	inferred from experiment	unknown	MEROPS	Rocken C	Stix B et al.:Proteolysis of AA amyloid fibri... (M10.001)	11485914,
MMP1_HUMAN	75	AEVI.\|.ISNA	inferred from experiment	unknown	MEROPS	Rocken C	Stix B et al.:Proteolysis of AA amyloid fibri... (M10.001)	11485914,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)