TopFIND 4.0

P80098: C-C motif chemokine 7

General Information

Protein names	- C-C motif chemokine 7 - Monocyte chemoattractant protein 3 - Monocyte chemotactic protein 3 - MCP-3 - NC28 - Small-inducible cytokine A7
Gene names	CCL7
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P80098

5

N-termini

4

C-termini

17

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MKASAALLCL LLTAAAFSPQ GLAQPVGINT STTCCYRFIN KKIPKQRLES YRRTTSSHCP
70 80 90
REAVIFKTKL DKEICADPTQ KWVQDFMKHL DKKTQTPKL

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 4 C-termini - 17 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P80098-5-unknown	AALLCL...	5		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34823
P80098-5-unknown	AALLCL...	5		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34847
P80098-5-unknown	AALLCL...	5		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34875
P80098-5-unknown	AALLCL...	5		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34911
P80098-5-unknown	AALLCL...	5		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34934
P80098-5-unknown	AALLCL...	5		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34953
P80098-5-unknown	AALLCL...	5		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC35010
P80098-5-unknown	AALLCL...	5		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC35032
P80098-7-unknown	LLCLLL...	7		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34895
P80098-7-unknown	LLCLLL...	7		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34954
P80098-9-unknown	CLLLTA...	9		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34896
P80098-24-Pyrrolidone carboxylic acid	QPVGIN...	24	pyrrolidone carboxylic acid-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P80098-28-unknown	INTSTT...	28		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC21795
P80098-28-unknown	INTSTT...	28		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC26455
P80098-28-unknown	INTSTT...	28		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC21616
P80098-28-unknown	INTSTT...	28		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23940
P80098-28-unknown	INTSTT...	28		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC21422
P80098-28-unknown	INTSTT...	28		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23272

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...KASAAL	6	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34895
	...KASAAL	6	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34954
	...SAALLC	8	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC34896
	...AQPVGI	27	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC21795
	...AQPVGI	27	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC26455
	...AQPVGI	27	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC21616
	...AQPVGI	27	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23940
	...AQPVGI	27	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC21422
	...AQPVGI	27	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23272
	...QTPKL	99	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
MMP1_HUMAN	4	KASA.\|.AALL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP12_HUMAN	4	KASA.\|.AALL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP13_HUMAN	4	KASA.\|.AALL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP2_HUMAN	4	KASA.\|.AALL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP3_HUMAN	4	KASA.\|.AALL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP7_HUMAN	4	KASA.\|.AALL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP9_HUMAN	4	KASA.\|.AALL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP25_HUMAN	4	KASA.\|.AALL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012B	22367194,
MMP14_HUMAN	6	SAAL.\|.LLCL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP7_HUMAN	6	SAAL.\|.LLCL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP14_HUMAN	8	ALLC.\|.CLLL		MS other		Overall Lab	recMMP-Chemokine_AStarr2012A	22147696,
MMP1_HUMAN	27	PVGI.\|.INTS	inferred from experiment	unknown	MEROPS	Overall CM	McQuibban GA et al.:Matrix metalloproteinase proces... (M10.013)	12149192,
MMP9_HUMAN	27	PVGI.\|.INTS	inferred from experiment	unknown	MEROPS	Overall CM	Prudova A et al.:Multiplex N-terminome analysis ... (M10.004)	20305284,
MMP14_HUMAN	27	PVGI.\|.INTS	inferred from experiment	unknown	MEROPS	Overall CM	McQuibban GA et al.:Matrix metalloproteinase proces... (M10.013)	12149192,
MMP3_HUMAN	27	PVGI.\|.INTS	inferred from experiment	unknown	MEROPS	Overall CM	McQuibban GA et al.:Matrix metalloproteinase proces... (M10.013)	12149192,
MMP13_HUMAN	27	PVGI.\|.INTS	inferred from experiment	unknown	MEROPS	Overall CM	McQuibban GA et al.:Matrix metalloproteinase proces... (M10.013)	12149192,
MMP2_HUMAN	27	PVGI.\|.INTS	inferred from experiment	unknown	MEROPS	Overall CM	McQuibban GA et al.:Matrix metalloproteinase proces... (M10.013)	12149192,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)