TopFIND 4.0

P14780: Matrix metalloproteinase-9

General Information

Protein names
- Matrix metalloproteinase-9
- MMP-9
- 3.4.24.35
- 92 kDa gelatinase
- 92 kDa type IV collagenase {ECO:0000303|PubMed:2551898}
- Gelatinase B
- GELB
- 67 kDa matrix metalloproteinase-9
- 82 kDa matrix metalloproteinase-9
Gene names MMP9
Organism Homo sapiens
Protease Family M10.004
Protease ID M10.004
Chromosome location
UniProt ID P14780

18

N-termini

20

C-termini

32

Cleavages

1376

Substrates

Sequence

        10         20         30         40         50         60 
MSLWQPLVLV LLVLGCCFAA PRQRQSTLVL FPGDLRTNLT DRQLAEEYLY RYGYTRVAEM 
        70         80         90        100        110        120 
RGESKSLGPA LLLLQKQLSL PETGELDSAT LKAMRTPRCG VPDLGRFQTF EGDLKWHHHN 
       130        140        150        160        170        180 
ITYWIQNYSE DLPRAVIDDA FARAFALWSA VTPLTFTRVY SRDADIVIQF GVAEHGDGYP 
       190        200        210        220        230        240 
FDGKDGLLAH AFPPGPGIQG DAHFDDDELW SLGKGVVVPT RFGNADGAAC HFPFIFEGRS 
       250        260        270        280        290        300 
YSACTTDGRS DGLPWCSTTA NYDTDDRFGF CPSERLYTQD GNADGKPCQF PFIFQGQSYS 
       310        320        330        340        350        360 
ACTTDGRSDG YRWCATTANY DRDKLFGFCP TRADSTVMGG NSAGELCVFP FTFLGKEYST 
       370        380        390        400        410        420 
CTSEGRGDGR LWCATTSNFD SDKKWGFCPD QGYSLFLVAA HEFGHALGLD HSSVPEALMY 
       430        440        450        460        470        480 
PMYRFTEGPP LHKDDVNGIR HLYGPRPEPE PRPPTTTTPQ PTAPPTVCPT GPPTVHPSER 
       490        500        510        520        530        540 
PTAGPTGPPS AGPTGPPTAG PSTATTVPLS PVDDACNVNI FDAIAEIGNQ LYLFKDGKYW 
       550        560        570        580        590        600 
RFSEGRGSRP QGPFLIADKW PALPRKLDSV FEERLSKKLF FFSGRQVWVY TGASVLGPRR 
       610        620        630        640        650        660 
LDKLGLGADV AQVTGALRSG RGKMLLFSGR RLWRFDVKAQ MVDPRSASEV DRMFPGVPLD 
       670        680        690        700    
THDVFQYREK AYFCQDRFYW RVSSRSELNQ VDQVGYVTYD ILQCPED

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

18 N-termini - 20 C-termini - 32 Cleavages - 1376 Substrates

N-termini

C-termini

Cleavages

Substrates