Q07325: C-X-C motif chemokine 9

General Information

Protein names	- C-X-C motif chemokine 9 - Gamma-interferon-induced monokine - Monokine induced by interferon-gamma - HuMIG - MIG - Small-inducible cytokine B9
Gene names	CXCL9
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q07325

6 N-termini

6 C-termini

7 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MKKSGVLFLL GIILLVLIGV QGTPVVRKGR CSCISTNQGT IHLQSLKDLK QFAPSPSCEK
        70         80         90        100        110        120
IEIIATLKNG VQTCLNPDSA DVKELIKKWE KQVSQKKKQK NGKKHQKKKV LKVRKSQRSR

QKKTT

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q07325-23-unknown	TPVVRK...	23	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q07325-25-unknown	VVRKGR...	25	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8502
Q07325-91-unknown	KQVSQK...	91	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35027
Q07325-113-unknown	VRKSQR...	113	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21280
Q07325-113-unknown	VRKSQR...	113	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26459
Q07325-113-unknown	VRKSQR...	113	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC24778
Q07325-116-unknown	SQRSRQ...	116	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26460
Q07325-117-unknown	QRSRQK...	117	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26461

Name

Sequence

Position

Modification

Evidence type

Method

Source (database)

Source (Lab)

Evidence name

Publications (PMID)

Q07325-23-unknown

TPVVRK...

inferred from electronic annotation

electronic annotation

UniProtKB

inferred from uniprot

Q07325-25-unknown

VVRKGR...

inferred from cleavage

unknown

TopFIND

Inferred from cleavage TC8502

Q07325-91-unknown

KQVSQK...

inferred from cleavage

unknown

TopFIND

Inferred from cleavage TC35027

Q07325-113-unknown

VRKSQR...

113

inferred from cleavage

unknown

TopFIND

Inferred from cleavage TC21280

Q07325-113-unknown

VRKSQR...

113

inferred from cleavage

unknown

TopFIND

Inferred from cleavage TC26459

Q07325-113-unknown

VRKSQR...

113

inferred from cleavage

unknown

TopFIND

Inferred from cleavage TC24778

Q07325-116-unknown

SQRSRQ...

116

inferred from cleavage

unknown

TopFIND

Inferred from cleavage TC26460

Q07325-117-unknown

QRSRQK...

117

inferred from cleavage

unknown

TopFIND

Inferred from cleavage TC26461

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VQGTPV	24	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8502
...IKKWEK	90	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC35027
...KKVLKV	112	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC21280
...KKVLKV	112	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26459
...KKVLKV	112	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC24778
...LKVRKS	115	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26460
...KVRKSQ	116	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26461
...QKKTT	125	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
DPP4_HUMAN	24	GTPV.\|.VVRK	inferred from experiment	unknown	MEROPS	De Meester I	Lambeir AM et al.:Kinetic investigation of chemok... (S09.003)	11390394,
MMP25_HUMAN	90	KWEK.\|.KQVS		MS other		Overall Lab	recMMP-Chemokine_AStarr2012B	22367194,
MMP12_HUMAN	112	VLKV.\|.VRKS	inferred from experiment	unknown	MEROPS	Overall CM	Cox JH et al.:Matrix metalloproteinase proces... (M10.009)	18411283,
MMP9_HUMAN	112	VLKV.\|.VRKS	inferred from experiment	unknown	MEROPS	Opdenakker G	Van den Steen PE et al.:Carboxyterminal cleavage of the... (M10.002)	14550288,
MMP7_HUMAN	112	VLKV.\|.VRKS	inferred from experiment	unknown	MEROPS	Overall CM	Cox JH et al.:Matrix metalloproteinase proces... (M10.009)	18411283,
MMP9_HUMAN	115	VRKS.\|.SQRS	inferred from experiment	unknown	MEROPS	Opdenakker G	Van den Steen PE et al.:Carboxyterminal cleavage of the... (M10.002)	14550288,
MMP9_HUMAN	116	RKSQ.\|.QRSR	inferred from experiment	unknown	MEROPS	Opdenakker G	Van den Steen PE et al.:Carboxyterminal cleavage of the... (M10.002)	14550288,

Protease

Position

Sequence

Evidence type

Method

Source (database)

Source (Lab)

Evidence name

Publications (PMIDs)

DPP4_HUMAN

GTPV.|.VVRK

inferred from experiment

unknown

MEROPS

De Meester I

Lambeir AM et al.:Kinetic investigation of chemok... (S09.003)

11390394,

MMP25_HUMAN

KWEK.|.KQVS

MS other

Overall Lab

recMMP-Chemokine_AStarr2012B

22367194,

MMP12_HUMAN

112

VLKV.|.VRKS

inferred from experiment

unknown

MEROPS

Overall CM

Cox JH et al.:Matrix metalloproteinase proces... (M10.009)

18411283,

MMP9_HUMAN

112

VLKV.|.VRKS

inferred from experiment

unknown

MEROPS

Opdenakker G

Van den Steen PE et al.:Carboxyterminal cleavage of the... (M10.002)

14550288,

MMP7_HUMAN

112

VLKV.|.VRKS

inferred from experiment

unknown

MEROPS

Overall CM

Cox JH et al.:Matrix metalloproteinase proces... (M10.009)

18411283,

MMP9_HUMAN

115

VRKS.|.SQRS

inferred from experiment

unknown

MEROPS

Opdenakker G

Van den Steen PE et al.:Carboxyterminal cleavage of the... (M10.002)

14550288,

MMP9_HUMAN

116

RKSQ.|.QRSR

inferred from experiment

unknown

MEROPS

Opdenakker G

Van den Steen PE et al.:Carboxyterminal cleavage of the... (M10.002)

14550288,

TopFIND

Q07325: C-X-C motif chemokine 9

General Information

6

N-termini

6

C-termini

7

Cleavages

0

Substrates

Sequence

Isoforms

Filter Information:

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 6 C-termini - 7 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

Substrates