TopFIND 4.0

P27487: Dipeptidyl peptidase 4

General Information

Protein names
- Dipeptidyl peptidase 4
- 3.4.14.5 {ECO:0000269|PubMed:10593948}
- ADABP
- Adenosine deaminase complexing protein 2
- ADCP-2
- Dipeptidyl peptidase IV
- DPP IV
- T-cell activation antigen CD26
- TP103
- CD26
- Dipeptidyl peptidase 4 membrane form
- Dipeptidyl peptidase IV membrane form
- Dipeptidyl peptidase 4 soluble form
- Dipeptidyl peptidase IV soluble form
Gene names DPP4
Organism Homo sapiens
Protease Family S09.003
Protease ID S09.003
Chromosome location
UniProt ID P27487

2

N-termini

1

C-termini

0

Cleavages

29

Substrates

Sequence

        10         20         30         40         50         60 
MKTPWKVLLG LLGAAALVTI ITVPVVLLNK GTDDATADSR KTYTLTDYLK NTYRLKLYSL 
        70         80         90        100        110        120 
RWISDHEYLY KQENNILVFN AEYGNSSVFL ENSTFDEFGH SINDYSISPD GQFILLEYNY 
       130        140        150        160        170        180 
VKQWRHSYTA SYDIYDLNKR QLITEERIPN NTQWVTWSPV GHKLAYVWNN DIYVKIEPNL 
       190        200        210        220        230        240 
PSYRITWTGK EDIIYNGITD WVYEEEVFSA YSALWWSPNG TFLAYAQFND TEVPLIEYSF 
       250        260        270        280        290        300 
YSDESLQYPK TVRVPYPKAG AVNPTVKFFV VNTDSLSSVT NATSIQITAP ASMLIGDHYL 
       310        320        330        340        350        360 
CDVTWATQER ISLQWLRRIQ NYSVMDICDY DESSGRWNCL VARQHIEMST TGWVGRFRPS 
       370        380        390        400        410        420 
EPHFTLDGNS FYKIISNEEG YRHICYFQID KKDCTFITKG TWEVIGIEAL TSDYLYYISN 
       430        440        450        460        470        480 
EYKGMPGGRN LYKIQLSDYT KVTCLSCELN PERCQYYSVS FSKEAKYYQL RCSGPGLPLY 
       490        500        510        520        530        540 
TLHSSVNDKG LRVLEDNSAL DKMLQNVQMP SKKLDFIILN ETKFWYQMIL PPHFDKSKKY 
       550        560        570        580        590        600 
PLLLDVYAGP CSQKADTVFR LNWATYLAST ENIIVASFDG RGSGYQGDKI MHAINRRLGT 
       610        620        630        640        650        660 
FEVEDQIEAA RQFSKMGFVD NKRIAIWGWS YGGYVTSMVL GSGSGVFKCG IAVAPVSRWE 
       670        680        690        700        710        720 
YYDSVYTERY MGLPTPEDNL DHYRNSTVMS RAENFKQVEY LLIHGTADDN VHFQQSAQIS 
       730        740        750        760    
KALVDVGVDF QAMWYTDEDH GIASSTAHQH IYTHMSHFIK QCFSLP

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 29 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P27487-1-unknown MKTPWK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P27487-39-unknown SRKTYT... 39 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...CFSLP 766 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates