TopFIND 4.0

O14625: C-X-C motif chemokine 11

General Information

Protein names	- C-X-C motif chemokine 11 - Beta-R1 - H174 - Interferon gamma-inducible protein 9 - IP-9 - Interferon-inducible T-cell alpha chemoattractant - I-TAC - Small-inducible cytokine B11
Gene names	CXCL11
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	O14625

5

N-termini

5

C-termini

10

Cleavages

0

Substrates

Sequence

10 20 30 40 50 60
MSVKGMAIAL AVILCATVVQ GFPMFKRGRC LCIGPGVKAV KVADIEKASI MYPSNNCDKI
70 80 90
EVIITLKENK GQRCLNPKSK QARLIIKKVE RKNF

Isoforms

Sequence View

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Evidence Codes:

Methodology:

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Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

5 N-termini - 5 C-termini - 10 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
O14625-22-unknown	FPMFKR...	22		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
O14625-24-unknown	MFKRGR...	24		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8476
O14625-24-unknown	MFKRGR...	24		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8503
O14625-26-unknown	KRGRCL...	26		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19975
O14625-26-unknown	KRGRCL...	26		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC25104
O14625-26-unknown	KRGRCL...	26		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC24786
O14625-80-unknown	KQARLI...	80		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19976
O14625-80-unknown	KQARLI...	80		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC25105
O14625-80-unknown	KQARLI...	80		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23950
O14625-80-unknown	KQARLI...	80		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC24787
O14625-85-unknown	IIKKVE...	85		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC24788

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...VQGFPM	23	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8476
	...VQGFPM	23	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8503
	...GFPMFK	25	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19975
	...GFPMFK	25	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC25104
	...GFPMFK	25	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC24786
	...LNPKSK	79	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19976
	...LNPKSK	79	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC25105
	...LNPKSK	79	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC23950
	...LNPKSK	79	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC24787
	...KQARLI	84	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC24788
	...ERKNF	94	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
DPP4_HUMAN	23	GFPM.\|.MFKR	inferred from experiment	unknown	MEROPS	De Meester I	Lambeir AM et al.:Kinetic investigation of chemok... (S09.003)	11390394,
DPP8_HUMAN	23	GFPM.\|.MFKR	inferred from experiment	unknown	MEROPS	Gorrell MD	Ajami K et al.:Stromal cell-derived factors 1a... (S09.003)	18275857,
MMP12_HUMAN	25	PMFK.\|.KRGR	inferred from experiment	unknown	MEROPS	Overall CM	Cox JH et al.:Matrix metalloproteinase proces... (M10.009)	18411283,
MMP9_HUMAN	25	PMFK.\|.KRGR	inferred from experiment	unknown	MEROPS	Overall CM	Cox JH et al.:Matrix metalloproteinase proces... (M10.009)	18411283,
MMP8_HUMAN	25	PMFK.\|.KRGR	inferred from experiment	unknown	MEROPS	Overall CM	Cox JH et al.:Matrix metalloproteinase proces... (M10.009)	18411283,
MMP12_HUMAN	79	PKSK.\|.KQAR	inferred from experiment	unknown	MEROPS	Overall CM	Cox JH et al.:Matrix metalloproteinase proces... (M10.009)	18411283,
MMP9_HUMAN	79	PKSK.\|.KQAR	inferred from experiment	unknown	MEROPS	Overall CM	Cox JH et al.:Matrix metalloproteinase proces... (M10.009)	18411283,
MMP7_HUMAN	79	PKSK.\|.KQAR	inferred from experiment	unknown	MEROPS	Overall CM	Cox JH et al.:Matrix metalloproteinase proces... (M10.009)	18411283,
MMP8_HUMAN	79	PKSK.\|.KQAR	inferred from experiment	unknown	MEROPS	Overall CM	Cox JH et al.:Matrix metalloproteinase proces... (M10.009)	18411283,
MMP8_HUMAN	84	ARLI.\|.IIKK	inferred from experiment	unknown	MEROPS	Overall CM	Cox JH et al.:Matrix metalloproteinase proces... (M10.009)	18411283,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)