TopFIND 4.0

P22894: Neutrophil collagenase

General Information

Protein names
- Neutrophil collagenase
- 3.4.24.34
- Matrix metalloproteinase-8
- MMP-8
- PMNL collagenase
- PMNL-CL
Gene names MMP8
Organism Homo sapiens
Protease Family M10.002
Protease ID M10.002
Chromosome location
UniProt ID P22894

6

N-termini

6

C-termini

9

Cleavages

336

Substrates

Sequence

        10         20         30         40         50         60 
MFSLKTLPFL LLLHVQISKA FPVSSKEKNT KTVQDYLEKF YQLPSNQYQS TRKNGTNVIV 
        70         80         90        100        110        120 
EKLKEMQRFF GLNVTGKPNE ETLDMMKKPR CGVPDSGGFM LTPGNPKWER TNLTYRIRNY 
       130        140        150        160        170        180 
TPQLSEAEVE RAIKDAFELW SVASPLIFTR ISQGEADINI AFYQRDHGDN SPFDGPNGIL 
       190        200        210        220        230        240 
AHAFQPGQGI GGDAHFDAEE TWTNTSANYN LFLVAAHEFG HSLGLAHSSD PGALMYPNYA 
       250        260        270        280        290        300 
FRETSNYSLP QDDIDGIQAI YGLSSNPIQP TGPSTPKPCD PSLTFDAITT LRGEILFFKD 
       310        320        330        340        350        360 
RYFWRRHPQL QRVEMNFISL FWPSLPTGIQ AAYEDFDRDL IFLFKGNQYW ALSGYDILQG 
       370        380        390        400        410        420 
YPKDISNYGF PSSVQAIDAA VFYRSKTYFF VNDQFWRYDN QRQFMEPGYP KSISGAFPGI 
       430        440        450        460    
ESKVDAVFQQ EHFFHVFSGP RYYAFDLIAQ RVTRVARGNK WLNCRYG

Isoforms



Sequence View



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

6 N-termini - 6 C-termini - 9 Cleavages - 336 Substrates

N-termini

C-termini

Cleavages

Substrates