P01019: Angiotensinogen

General Information

Protein names	- Angiotensinogen - Serpin A8 - Angiotensin-1 - Angiotensin 1-10 - Angiotensin I - Ang I - Angiotensin-2 - Angiotensin 1-8 - Angiotensin II - Ang II - Angiotensin-3 - Angiotensin 2-8 - Angiotensin III - Ang III - Des-Asp1]-angiotensin II - Angiotensin-4 - Angiotensin 3-8 - Angiotensin IV - Ang IV - Angiotensin 1-9 - Angiotensin 1-7 - Angiotensin 1-5 - Angiotensin 1-4
Gene names	AGT
Organism	Homo sapiens
Protease Family
Protease ID	I04.953
Chromosome location
UniProt ID	P01019

13 N-termini

12 C-termini

63 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MRKRAPQSEM APAGVSLRAT ILCLLAWAGL AAGDRVYIHP FHLVIHNEST CEQLAKANAG
        70         80         90        100        110        120
KPKDPTFIPA PIQAKTSPVD EKALQDQLVL VAAKLDTEDK LRAAMVGMLA NFLGFRIYGM
       130        140        150        160        170        180
HSELWGVVHG ATVLSPTAVF GTLASLYLGA LDHTADRLQA ILGVPWKDKN CTSRLDAHKV
       190        200        210        220        230        240
LSALQAVQGL LVAQGRADSQ AQLLLSTVVG VFTAPGLHLK QPFVQGLALY TPVVLPRSLD
       250        260        270        280        290        300
FTELDVAAEK IDRFMQAVTG WKTGCSLMGA SVDSTLAFNT YVHFQGKMKG FSLLAEPQEF
       310        320        330        340        350        360
WVDNSTSVSV PMLSGMGTFQ HWSDIQDNFS VTQVPFTESA CLLLIQPHYA SDLDKVEGLT
       370        380        390        400        410        420
FQQNSLNWMK KLSPRTIHLT MPQLVLQGSY DLQDLLAQAE LPAILHTELN LQKLSNDRIR
       430        440        450        460        470        480
VGEVLNSIFF ELEADEREPT ESTQQLNKPE VLEVTLNRPF LFAVYDQSAT ALHFLGRVAN

PLSTA

Isoforms

Sequence View

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Evidence Codes:

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Protein Neighborhood

Domains & Features

13 N-termini - 12 C-termini - 63 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name	Publications (PMID)
P01019-34-unknown	DRVYIH...	34	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P01019-35-unknown	RVYIHP...	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8459
P01019-35-unknown	RVYIHP...	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9543
P01019-35-unknown	RVYIHP...	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC230
P01019-36-unknown	VYIHPF...	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC261
P01019-36-unknown	VYIHPF...	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8468
P01019-36-unknown	VYIHPF...	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26665
P01019-36-unknown	VYIHPF...	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16704
P01019-36-unknown	VYIHPF...	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9544
P01019-36-unknown	VYIHPF...	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9548
P01019-36-unknown	VYIHPF...	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC231
P01019-36-unknown	VYIHPF...	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC247
P01019-36-unknown	VYIHPF...	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC248
P01019-37-unknown	YIHPFH...	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8469
P01019-37-unknown	YIHPFH...	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26666
P01019-37-unknown	YIHPFH...	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16705
P01019-37-unknown	YIHPFH...	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8514
P01019-37-unknown	YIHPFH...	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9545
P01019-37-unknown	YIHPFH...	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9549
P01019-37-unknown	YIHPFH...	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31887
P01019-37-unknown	YIHPFH...	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8634
P01019-38-unknown	IHPFHL...	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8470
P01019-38-unknown	IHPFHL...	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26667
P01019-38-unknown	IHPFHL...	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8515
P01019-38-unknown	IHPFHL...	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9546
P01019-38-unknown	IHPFHL...	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9550
P01019-38-unknown	IHPFHL...	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4745
P01019-38-unknown	IHPFHL...	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31888
P01019-38-unknown	IHPFHL...	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31909
P01019-38-unknown	IHPFHL...	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8366
P01019-38-unknown	IHPFHL...	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19894
P01019-38-unknown	IHPFHL...	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31679
P01019-38-unknown	IHPFHL...	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27630
P01019-39-unknown	HPFHLV...	39	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8471
P01019-39-unknown	HPFHLV...	39	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9547
P01019-39-unknown	HPFHLV...	39	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9551
P01019-40-unknown	PFHLVI...	40	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3329
P01019-41-unknown	FHLVIH...	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1
P01019-41-unknown	FHLVIH...	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26668
P01019-41-unknown	FHLVIH...	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8516
P01019-41-unknown	FHLVIH...	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8582
P01019-41-unknown	FHLVIH...	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31889
P01019-41-unknown	FHLVIH...	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26793
P01019-41-unknown	FHLVIH...	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19895
P01019-41-unknown	FHLVIH...	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31680
P01019-41-unknown	FHLVIH...	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC24792
P01019-41-unknown	FHLVIH...	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27610
P01019-41-unknown	FHLVIH...	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27631
P01019-42-unknown	HLVIHN...	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3330
P01019-42-unknown	HLVIHN...	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8255
P01019-42-unknown	HLVIHN...	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27770
P01019-42-unknown	HLVIHN...	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4746
P01019-42-unknown	HLVIHN...	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8340
P01019-42-unknown	HLVIHN...	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8367
P01019-42-unknown	HLVIHN...	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8635
P01019-42-unknown	HLVIHN...	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC24793
P01019-43-unknown	LVIHNE...	43	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2
P01019-43-unknown	LVIHNE...	43	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8216
P01019-43-unknown	LVIHNE...	43	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8219
P01019-43-unknown	LVIHNE...	43	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8256
P01019-43-unknown	LVIHNE...	43	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27628
P01019-44-unknown	VIHNES...	44	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31570
P01019-45-unknown	IHNEST...	45	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27771
P01019-45-unknown	IHNEST...	45	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8636
P01019-238-unknown	SLDFTE...	238		unknown		Wildes D. et al: Sampling the N-terminal proteome of human blood	20173099

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LAAGDR	34	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8459
...LAAGDR	34	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9543
...LAAGDR	34	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC230
...AAGDRV	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC261
...AAGDRV	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8468
...AAGDRV	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26665
...AAGDRV	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16704
...AAGDRV	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9544
...AAGDRV	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9548
...AAGDRV	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC231
...AAGDRV	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC247
...AAGDRV	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC248
...AGDRVY	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8469
...AGDRVY	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26666
...AGDRVY	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16705
...AGDRVY	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8514
...AGDRVY	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9545
...AGDRVY	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9549
...AGDRVY	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31887
...AGDRVY	36	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8634
...GDRVYI	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8470
...GDRVYI	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26667
...GDRVYI	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8515
...GDRVYI	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9546
...GDRVYI	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9550
...GDRVYI	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4745
...GDRVYI	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31888
...GDRVYI	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31909
...GDRVYI	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8366
...GDRVYI	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19894
...GDRVYI	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31679
...GDRVYI	37	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27630
...DRVYIH	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8471
...DRVYIH	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9547
...DRVYIH	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC9551
...RVYIHP	39	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3329
...VYIHPF	40	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC1
...VYIHPF	40	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26668
...VYIHPF	40	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8516
...VYIHPF	40	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8582
...VYIHPF	40	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31889
...VYIHPF	40	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC26793
...VYIHPF	40	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19895
...VYIHPF	40	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31680
...VYIHPF	40	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC24792
...VYIHPF	40	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27610
...VYIHPF	40	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27631
...YIHPFH	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC3330
...YIHPFH	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8255
...YIHPFH	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27770
...YIHPFH	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4746
...YIHPFH	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8340
...YIHPFH	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8367
...YIHPFH	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8635
...YIHPFH	41	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC24793
...IHPFHL	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2
...IHPFHL	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8216
...IHPFHL	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8219
...IHPFHL	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8256
...IHPFHL	42	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27628
...HPFHLV	43	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC31570
...PFHLVI	44	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC27771
...PFHLVI	44	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8636
...PLSTA	485	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
DNPEP_HUMAN	34	AGDR.\|.RVYI	inferred from experiment	unknown	MEROPS	Neidle A	Kelly JA et al.:An aminopeptidase from mouse br... (M18.002)	6854330,
ERAP1_HUMAN	34	AGDR.\|.RVYI	inferred from experiment	unknown	MEROPS		Merops ERAP1_HUMAN -> ANGT_HUMAN @34
AMPE_HUMAN	34	AGDR.\|.RVYI	inferred from experiment	unknown	MEROPS	Tsujimoto M	Goto Y et al.:Asparatic acid 221 is critical ... (M01.003)	17932029,
AMZ2_HUMAN	35	GDRV.\|.VYIH	inferred from experiment	unknown	MEROPS	Lopez-Otin C	Diaz-Perales A et al.:Identification and characteriza... (M54.002)	15972818,
DPP3_HUMAN	35	GDRV.\|.VYIH	inferred from experiment	unknown	MEROPS		Merops DPP3_HUMAN -> ANGT_HUMAN @35
NEP_HUMAN	35	GDRV.\|.VYIH	inferred from experiment	unknown	MEROPS	Hersh LB	Gafford JT et al.:Human kidney "enkephalinase", a... (M13.001)	6349683,
LCAP_HUMAN	35	GDRV.\|.VYIH	inferred from experiment	unknown	MEROPS		Merops LCAP_HUMAN -> ANGT_HUMAN @35
ERAP1_HUMAN	35	GDRV.\|.VYIH	inferred from experiment	unknown	MEROPS		Merops ERAP1_HUMAN -> ANGT_HUMAN @35
ERAP2_HUMAN	35	GDRV.\|.VYIH	inferred from experiment	unknown	MEROPS	Tsujimoto M	Tanioka T et al.:Human leukocyte-derived arginin... (M01.024)	12799365,
AMPE_HUMAN	35	GDRV.\|.VYIH	inferred from experiment	unknown	MEROPS	Tsujimoto M	Goto Y et al.:Asparatic acid 221 is critical ... (M01.003)	17932029,
AMPO_HUMAN	35	GDRV.\|.VYIH	inferred from experiment	unknown	MEROPS	Lopez-Otin C	Diaz-Perales A et al.:Identification of human aminope... (M01.028)	15687497,
AMPQ_HUMAN	35	GDRV.\|.VYIH	inferred from experiment	unknown	MEROPS	Tsujimoto M	Maruyama M et al.:Laeverin/aminopeptidase Q, a no... (M01.026)	17525158,
DPP3_HUMAN	36	DRVY.\|.YIHP	inferred from experiment	unknown	MEROPS		Merops DPP3_HUMAN -> ANGT_HUMAN @36
NEP_HUMAN	36	DRVY.\|.YIHP	inferred from experiment	unknown	MEROPS	Hersh LB	Gafford JT et al.:Human kidney "enkephalinase", a... (M13.001)	6349683,
LCAP_HUMAN	36	DRVY.\|.YIHP	inferred from experiment	unknown	MEROPS		Merops LCAP_HUMAN -> ANGT_HUMAN @36
ECE1_HUMAN	36	DRVY.\|.YIHP	inferred from experiment	unknown	MEROPS	Turner AJ	Carson JA et al.:Characterization of PgPepO, a b... (M13.002)	12193062,
ERAP1_HUMAN	36	DRVY.\|.YIHP	inferred from experiment	unknown	MEROPS		Merops ERAP1_HUMAN -> ANGT_HUMAN @36
ERAP2_HUMAN	36	DRVY.\|.YIHP	inferred from experiment	unknown	MEROPS	Tsujimoto M	Tanioka T et al.:Human leukocyte-derived arginin... (M01.024)	12799365,
TPP1_HUMAN	36	DRVY.\|.YIHP	inferred from experiment	unknown	MEROPS	Ohkubo I	Du PG et al.:Rat tripeptidyl peptidase I: mo... (S53.003)	11843185,
ELNE_HUMAN	36	DRVY.\|.YIHP	inferred from experiment	unknown	MEROPS	Patston PA	Ramaha A et al.:Release and degradation of angi... (S01.131)	11747312,
DPP3_HUMAN	37	RVYI.\|.IHPF	inferred from experiment	unknown	MEROPS		Merops DPP3_HUMAN -> ANGT_HUMAN @37
NEP_HUMAN	37	RVYI.\|.IHPF	inferred from experiment	unknown	MEROPS	Hersh LB	Gafford JT et al.:Human kidney "enkephalinase", a... (M13.001)	6349683,
ECE1_HUMAN	37	RVYI.\|.IHPF	inferred from experiment	unknown	MEROPS	Turner AJ	Carson JA et al.:Characterization of PgPepO, a b... (M13.002)	12193062,
ERAP1_HUMAN	37	RVYI.\|.IHPF	inferred from experiment	unknown	MEROPS		Merops ERAP1_HUMAN -> ANGT_HUMAN @37
ERAP2_HUMAN	37	RVYI.\|.IHPF	inferred from experiment	unknown	MEROPS	Tsujimoto M	Tanioka T et al.:Human leukocyte-derived arginin... (M01.024)	12799365,
CATG_HUMAN	37	RVYI.\|.IHPF	inferred from experiment	unknown	MEROPS	Caughey GH	Raymond WW et al.:How immune peptidases change sp... (S01.133)	20889553,
TPP1_HUMAN	37	RVYI.\|.IHPF	inferred from experiment	unknown	MEROPS		Merops TPP1_HUMAN -> ANGT_HUMAN @37
TPP2_HUMAN	37	RVYI.\|.IHPF	inferred from experiment	unknown	MEROPS	McDermott JR	Wilson C et al.:Purification and characterizati... (S08.090)	8396212,
CMA1_HUMAN	37	RVYI.\|.IHPF	inferred from experiment	unknown	MEROPS	Caughey GH	Raymond WW et al.:Albumin is a substrate of human... (S01.140)	12815038,
MMEL1_HUMAN	37	RVYI.\|.IHPF	inferred from experiment	unknown	MEROPS	Ouimet T	Rose C et al.:Cell-specific activity of nepri... (M13.008)	11964170,
THOP1_HUMAN	37	RVYI.\|.IHPF	inferred from experiment	unknown	MEROPS	Barrett AJ	Dando PM et al.:Human thimet oligopeptidase.... (M03.001)	8373360,
PREP_HUMAN	37	RVYI.\|.IHPF	inferred from experiment	unknown	MEROPS	Hersh LB	Chow KM et al.:Mammalian pitrilysin: substrate... (M16.009)	19196155,
DPP3_HUMAN	38	VYIH.\|.HPFH	inferred from experiment	unknown	MEROPS		Merops DPP3_HUMAN -> ANGT_HUMAN @38
ERAP1_HUMAN	38	VYIH.\|.HPFH	inferred from experiment	unknown	MEROPS		Merops ERAP1_HUMAN -> ANGT_HUMAN @38
ERAP2_HUMAN	38	VYIH.\|.HPFH	inferred from experiment	unknown	MEROPS	Tsujimoto M	Tanioka T et al.:Human leukocyte-derived arginin... (M01.024)	12799365,
CATB_HUMAN	39	YIHP.\|.PFHL	inferred from experiment	unknown	MEROPS	Tang J	Takahashi T et al.:Porcine spleen cathepsin B is a... (C01.060)	3522589,
ACE2_HUMAN	40	IHPF.\|.FHLV	inferred from experiment	unknown	MEROPS	Tummino P	Vickers C et al.:Hydrolysis of biological peptid... (M02.006)	11815627,
NEP_HUMAN	40	IHPF.\|.FHLV	inferred from experiment	unknown	MEROPS	Hersh LB	Gafford JT et al.:Human kidney "enkephalinase", a... (M13.001)	6349683,
ECE1_HUMAN	40	IHPF.\|.FHLV	inferred from experiment	unknown	MEROPS	Turner AJ	Carson JA et al.:Characterization of PgPepO, a b... (M13.002)	12193062,
ECE2_HUMAN	40	IHPF.\|.FHLV	inferred from experiment	unknown	MEROPS	Devi LA	Mzhavia N et al.:Characterization of endothelin-... (M13.003)	12560336,
TPP1_HUMAN	40	IHPF.\|.FHLV	inferred from experiment	unknown	MEROPS	Warburton MJ	Vines D et al.:Purification and characterisati... (S53.003)	9659384,
PCP_HUMAN	40	IHPF.\|.FHLV	inferred from experiment	unknown	MEROPS		Merops PCP_HUMAN -> ANGT_HUMAN @40
MMEL1_HUMAN	40	IHPF.\|.FHLV	inferred from experiment	unknown	MEROPS	Ouimet T	Rose C et al.:Cell-specific activity of nepri... (M13.008)	11964170,
THOP1_HUMAN	40	IHPF.\|.FHLV	inferred from experiment	unknown	MEROPS	Barrett AJ	Dando PM et al.:Human thimet oligopeptidase.... (M03.001)	8373360,
MMP8_HUMAN	40	IHPF.\|.FHLV	inferred from experiment	unknown	MEROPS	Tschesche H	Diekmann O et al.:Degradation of kinins, angioten... (M10.002)	7538373,
PPCE_HUMAN	40	IHPF.\|.FHLV	inferred from experiment	unknown	MEROPS	Walter R	Koida M et al.:Post-proline cleaving enzyme. P... (S09.001)	12173,
PREP_HUMAN	40	IHPF.\|.FHLV	inferred from experiment	unknown	MEROPS	Hersh LB	Chow KM et al.:Mammalian pitrilysin: substrate... (M16.009)	19196155,
CATB_HUMAN	41	HPFH.\|.HLVI	inferred from experiment	unknown	MEROPS	Tang J	Takahashi T et al.:Porcine spleen cathepsin B is a... (C01.060)	3522589,
CBPA6_HUMAN	41	HPFH.\|.HLVI	inferred from experiment	unknown	MEROPS	Fricker LD	Lyons PJ et al.:Characterization of carboxypept... (M14.018)	18178555,
PRTN3_HUMAN	41	HPFH.\|.HLVI	inferred from experiment	unknown	MEROPS	Patston PA	Ramaha A et al.:Release and degradation of angi... (S01.133)	11747312,
CATG_HUMAN	41	HPFH.\|.HLVI	inferred from experiment	unknown	MEROPS	Patston PA	Ramaha A et al.:Release and degradation of angi... (S01.133)	11747312,
CEL2A_HUMAN	41	HPFH.\|.HLVI	inferred from experiment	unknown	MEROPS	Salgado MC	Becari C et al.:Role of elastase-2 as an angiot... (S01.155)	16160604,
CMA1_HUMAN	41	HPFH.\|.HLVI	inferred from experiment	unknown	MEROPS	Wolters PJ	Caughey GH et al.:Angiotensin II generation by ma... (S01.140)	10899625,
ELNE_HUMAN	41	HPFH.\|.HLVI	inferred from experiment	unknown	MEROPS	Patston PA	Ramaha A et al.:Release and degradation of angi... (S01.133)	11747312,
MMP8_HUMAN	41	HPFH.\|.HLVI	inferred from experiment	unknown	MEROPS	Tschesche H	Diekmann O et al.:Degradation of kinins, angioten... (M10.002)	7538373,
ACE2_HUMAN	42	PFHL.\|.LVIH	inferred from experiment	unknown	MEROPS	Tummino P	Vickers C et al.:Hydrolysis of biological peptid... (M02.006)	11815627,
CBPA3_HUMAN	42	PFHL.\|.LVIH	inferred from experiment	unknown	MEROPS		Merops CBPA3_HUMAN -> ANGT_HUMAN @42
CBPA4_HUMAN	42	PFHL.\|.LVIH	inferred from experiment	unknown	MEROPS	Fricker LD	Tanco S et al.:Characterization of the substra... (M14.017)	20385563,
CBPA6_HUMAN	42	PFHL.\|.LVIH	inferred from experiment	unknown	MEROPS	Fricker LD	Lyons PJ et al.:Characterization of carboxypept... (M14.018)	18178555,
PPGB_HUMAN	42	PFHL.\|.LVIH	inferred from experiment	unknown	MEROPS	Erdos EG	Jackman HL et al.:A peptidase in human platelets ... (S10.002)	1694176,
RENI_HUMAN	43	FHLV.\|.VIHN	inferred from experiment	unknown	MEROPS	Fukamizu A	Hatae T et al.:Comparative studies on species-... (A01.007)	8047064,
PRTN3_HUMAN	44	HLVI.\|.IHNE	inferred from experiment	unknown	MEROPS	Patston PA	Ramaha A et al.:Release and degradation of angi... (S01.131)	11747312,
ELNE_HUMAN	44	HLVI.\|.IHNE	inferred from experiment	unknown	MEROPS	Patston PA	Ramaha A et al.:Release and degradation of angi... (S01.131)	11747312,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)