TopFIND 4.0

Q9UI42: Carboxypeptidase A4

General Information

Protein names
- Carboxypeptidase A4
- 3.4.17.-
- Carboxypeptidase A3
Gene names CPA4
Organism Homo sapiens
Protease Family M14.017
Protease ID M14.017
Chromosome location
UniProt ID Q9UI42

3

N-termini

1

C-termini

0

Cleavages

36

Substrates

Sequence

        10         20         30         40         50         60 
MRWILFIGAL IGSSICGQEK FFGDQVLRIN VRNGDEISKL SQLVNSNNLK LNFWKSPSSF 
        70         80         90        100        110        120 
NRPVDVLVPS VSLQAFKSFL RSQGLEYAVT IEDLQALLDN EDDEMQHNEG QERSSNNFNY 
       130        140        150        160        170        180 
GAYHSLEAIY HEMDNIAADF PDLARRVKIG HSFENRPMYV LKFSTGKGVR RPAVWLNAGI 
       190        200        210        220        230        240 
HSREWISQAT AIWTARKIVS DYQRDPAITS ILEKMDIFLL PVANPDGYVY TQTQNRLWRK 
       250        260        270        280        290        300 
TRSRNPGSSC IGADPNRNWN ASFAGKGASD NPCSEVYHGP HANSEVEVKS VVDFIQKHGN 
       310        320        330        340        350        360 
FKGFIDLHSY SQLLMYPYGY SVKKAPDAEE LDKVARLAAK ALASVSGTEY QVGPTCTTVY 
       370        380        390        400        410        420 
PASGSSIDWA YDNGIKFAFT FELRDTGTYG FLLPANQIIP TAEETWLGLK TIMEHVRDNL 
   
Y

Isoforms

- Isoform 2 of Carboxypeptidase A4

Sequence View

        10         20         30         40         50         60 
MRWILFIGAL IGSSICGQEK FFGDQVLRIN VRNGDEISKL SQLVNSNNLK LNFWKSPSSF 
        70         80         90        100        110        120 
NRPVDVLVPS VSLQAFKSFL RSQGLEYAVT IEDLQALLDN EDDEMQHNEG QERSSNNFNY 
       130        140        150        160        170        180 
GAYHSLEAIY HEMDNIAADF PDLARRVKIG HSFENRPMYV LKFSTGKGVR RPAVWLNAGI 
       190        200        210        220        230        240 
HSREWISQAT AIWTARKIVS DYQRDPAITS ILEKMDIFLL PVANPDGYVY TQTQNRLWRK 
       250        260        270        280        290        300 
TRSRNPGSSC IGADPNRNWN ASFAGKGASD NPCSEVYHGP HANSEVEVKS VVDFIQKHGN 
       310        320        330        340        350        360 
FKGFIDLHSY SQLLMYPYGY SVKKAPDAEE LDKVARLAAK ALASVSGTEY QVGPTCTTVY 
       370        380        390        400        410        420 
PASGSSIDWA YDNGIKFAFT FELRDTGTYG FLLPANQIIP TAEETWLGLK TIMEHVRDNL 
   
Y



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 36 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q9UI42-1-unknown MRWILF... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt69426
    Q9UI42-17-unknown GQEKFF... 17 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q9UI42-17-unknown GQEKFF... 17 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt111916
    Q9UI42-114-unknown SSNNFN... 114 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RDNLY 421 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RDNLY 421 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt65044

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates