Q14738: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

General Information

Protein names	- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform - PP2A B subunit isoform B'-delta - PP2A B subunit isoform B56-delta - PP2A B subunit isoform PR61-delta - PP2A B subunit isoform R5-delta
Gene names	PPP2R5D
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q14738

1 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform Delta-2 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform - Isoform Delta-3 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

Sequence View

        10         20         30         40         50         60
MPYKLKKEKE PPKVAKCTAK PSSSGKDGGG ENTEEAQPQP QPQPQPQAQS QPPSSNKRPS
        70         80         90        100        110        120
NSTPPPTQLS KIKYSGGPQI VKKERRQSSS RFNLSKNREL QKLPALKDSP TQEREELFIQ
       130        140        150        160        170        180
KLRQCCVLFD FVSDPLSDLK FKEVKRAGLN EMVEYITHSR DVVTEAIYPE AVTMFSVNLF
       190        200        210        220        230        240
RTLPPSSNPT GAEFDPEEDE PTLEAAWPHL QLVYEFFLRF LESPDFQPNI AKKYIDQKFV
       250        260        270        280        290        300
LALLDLFDSE DPRERDFLKT ILHRIYGKFL GLRAYIRRQI NHIFYRFIYE TEHHNGIAEL
       310        320        330        340        350        360
LEILGSIING FALPLKEEHK MFLIRVLLPL HKVKSLSVYH PQLAYCVVQF LEKESSLTEP
       370        380        390        400        410        420
VIVGLLKFWP KTHSPKEVMF LNELEEILDV IEPSEFSKVM EPLFRQLAKC VSSPHFQVAE
       430        440        450        460        470        480
RALYYWNNEY IMSLISDNAA RVLPIMFPAL YRNSKSHWNK TIHGLIYNAL KLFMEMNQKL
       490        500        510        520        530        540
FDDCTQQYKA EKQKGRFRMK EREEMWQKIE ELARLNPQYP MFRAPPPLPP VYSMETETPT
       550        560        570        580        590        600
AEDIQLLKRT VETEAVQMLK DIKKEKVLLR RKSELPQDVY TIKALEAHKR AEEFLTASQE

AL         10         20         30         40         50         60
MPYKLKKEKE PPKVAKCTAK PSSSGKDGGG ENTEEAQPQP QPQPQPQAQS QPPSSNKRPS
        70         80         90        100        110        120
NSTPPPTQLS KIKYSGGPQI VKKERRQSSS RFNLSKNREL QKLPALKDSP TQEREELFIQ
       130        140        150        160        170        180
KLRQCCVLFD FVSDPLSDLK FKEVKRAGLN EMVEYITHSR DVVTEAIYPE AVTMFSVNLF
       190        200        210        220        230        240
RTLPPSSNPT GAEFDPEEDE PTLEAAWPHL QLVYEFFLRF LESPDFQPNI AKKYIDQKFV
       250        260        270        280        290        300
LALLDLFDSE DPRERDFLKT ILHRIYGKFL GLRAYIRRQI NHIFYRFIYE TEHHNGIAEL
       310        320        330        340        350        360
LEILGSIING FALPLKEEHK MFLIRVLLPL HKVKSLSVYH PQLAYCVVQF LEKESSLTEP
       370        380        390        400        410        420
VIVGLLKFWP KTHSPKEVMF LNELEEILDV IEPSEFSKVM EPLFRQLAKC VSSPHFQVAE
       430        440        450        460        470        480
RALYYWNNEY IMSLISDNAA RVLPIMFPAL YRNSKSHWNK TIHGLIYNAL KLFMEMNQKL
       490        500        510        520        530        540
FDDCTQQYKA EKQKGRFRMK EREEMWQKIE ELARLNPQYP MFRAPPPLPP VYSMETETPT
       550        560        570        580        590        600
AEDIQLLKRT VETEAVQMLK DIKKEKVLLR RKSELPQDVY TIKALEAHKR AEEFLTASQE

AL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

1 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q14738-1-unknown	MPYKLK...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q14738-1-unknown	MPYKLK...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt65731

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...ASQEAL	601	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8236
...ASQEAL	601	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt136795
...ASQEAL	601	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt137634
...SQEAL	602	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...SQEAL	602	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt61350
...SQEAL	602	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt61349
...SQEAL	602		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...SQEAL	602		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...SQEAL	602		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...SQEAL	602		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CBPA4_HUMAN	601	QEAL.\|.L	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)