Q9H6F5: Coiled-coil domain-containing protein 86

General Information

Protein names	- Coiled-coil domain-containing protein 86 - Cytokine-induced protein with coiled-coil domain
Gene names	CCDC86
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9H6F5

6 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDTPLRRSRR LGGLRPESPE SLTSVSRTRR ALVEFESNPE ETREPGSPPS VQRAGLGSPE
        70         80         90        100        110        120
RPPKTSPGSP RLQQGAGLES PQGQPEPGAA SPQRQQDLHL ESPQRQPEYS PESPRCQPKP
       130        140        150        160        170        180
SEEAPKCSQD QGVLASELAQ NKEELTPGAP QHQLPPVPGS PEPYPGQQAP GPEPSQPLLE
       190        200        210        220        230        240
LTPRAPGSPR GQHEPSKPPP AGETVTGGFG AKKRKGSSSQ APASKKLNKE ELPVIPKGKP
       250        260        270        280        290        300
KSGRVWKDRS KKRFSQMLQD KPLRTSWQRK MKERQERKLA KDFARHLEEE KERRRQEKKQ
       310        320        330        340        350        360
RRAENLKRRL ENERKAEVVQ VIRNPAKLKR AKKKQLRSIE KRDTLALLQK QPPQQPAAKI

Isoforms

- Isoform 2 of Coiled-coil domain-containing protein 86

Sequence View

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Evidence Names:

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Protein Neighborhood

Domains & Features

6 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9H6F5-1-unknown	MDTPLR...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9H6F5-13-	GLRPES...	13		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q9H6F5-31-	ALVEFE...	31		Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
Q9H6F5-191-	GQHEPS...	191		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9H6F5-254-	FSQMLQ...	254		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
Q9H6F5-257-unknown	MLQDKP...	257	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000440906

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...QPAAKI	359	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8253
...PAAKI	360		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...PAAKI	360	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...PAAKI	360		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
CBPA4_HUMAN	359	AAKI.\|.I	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)