P62750: 60S ribosomal protein L23a

General Information

Protein names	- 60S ribosomal protein L23a - Large ribosomal subunit protein uL23 {ECO:0000303\|PubMed:24524803}
Gene names	RPL23A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P62750

9 N-termini

4 C-termini

2 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAPKAKKEAP APPKAEAKAK ALKAKKAVLK GVHSHKKKKI RTSPTFRRPK TLRLRRQPKY
        70         80         90        100        110        120
PRKSAPRRNK LDHYAIIKFP LTTESAMKKI EDNNTLVFIV DVKANKHQIK QAVKKLYDID
       130        140        150
VAKVNTLIRP DGEKKAYVRL APDYDALDVA NKIGII

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

9 N-termini - 4 C-termini - 2 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P62750-2-unknown	APKAKK...	2	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P62750-2-unknown	APKAKK...	2	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P62750-7-	KEAPAP...	7		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P62750-7-unknown	KEAPAP...	7		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P62750-10-unknown	PAPPKA...	10	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P62750-26-unknown	KAVLKG...	26	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10135
P62750-75-unknown	AIIKFP...	75		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P62750-75-	AIIKFP...	75		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
P62750-87-unknown	MKKIED...	87	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000468172
P62750-87-unknown	MKKIED...	87	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000466425
P62750-140-	LAPDYD...	140		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...ALKAKK	25	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10135
...NKIGII	155	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8233
...KIGII	156	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...KIGII	156		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...KIGII	156		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...KIGII	156		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...KIGII	156		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	25	KAKK.\|.KAVL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
CBPA4_HUMAN	155	IGII.\|.I	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)