TopFIND 4.0

P12544: Granzyme A

General Information

Protein names
- Granzyme A
- 3.4.21.78
- CTL tryptase
- Cytotoxic T-lymphocyte proteinase 1
- Fragmentin-1
- Granzyme-1
- Hanukkah factor
- H factor
- HF
Gene names GZMA
Organism Homo sapiens
Protease Family S01.135
Protease ID S01.135
Chromosome location
UniProt ID P12544

1

N-termini

2

C-termini

1

Cleavages

745

Substrates

Sequence

        10         20         30         40         50         60 
MRNSYRFLAS SLSVVVSLLL IPEDVCEKII GGNEVTPHSR PYMVLLSLDR KTICAGALIA 
        70         80         90        100        110        120 
KDWVLTAAHC NLNKRSQVIL GAHSITREEP TKQIMLVKKE FPYPCYDPAT REGDLKLLQL 
       130        140        150        160        170        180 
MEKAKINKYV TILHLPKKGD DVKPGTMCQV AGWGRTHNSA SWSDTLREVN ITIIDRKVCN 
       190        200        210        220        230        240 
DRNHYNFNPV IGMNMVCAGS LRGGRDSCNG DSGSPLLCEG VFRGVTSFGL ENKCGDPRGP 
       250        260    
GVYILLSKKH LNWIIMTIKG AV

Isoforms

- Isoform beta of Granzyme A

Sequence View

        10         20         30         40         50         60 
MRNSYRFLAS SLSVVVSLLL IPEDVCEKII GGNEVTPHSR PYMVLLSLDR KTICAGALIA 
        70         80         90        100        110        120 
KDWVLTAAHC NLNKRSQVIL GAHSITREEP TKQIMLVKKE FPYPCYDPAT REGDLKLLQL 
       130        140        150        160        170        180 
MEKAKINKYV TILHLPKKGD DVKPGTMCQV AGWGRTHNSA SWSDTLREVN ITIIDRKVCN 
       190        200        210        220        230        240 
DRNHYNFNPV IGMNMVCAGS LRGGRDSCNG DSGSPLLCEG VFRGVTSFGL ENKCGDPRGP 
       250        260    
GVYILLSKKH LNWIIMTIKG AV



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(REFRESH)

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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 1 Cleavages - 745 Substrates

N-termini

C-termini

Cleavages

Substrates