Q6FI13: Histone H2A type 2-A

General Information

Protein names	- Histone H2A type 2-A - Histone H2A.2 - Histone H2A/o
Gene names	HIST2H2AA4
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6FI13

6 N-termini

5 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSGRGKQGGK ARAKAKSRSS RAGLQFPVGR VHRLLRKGNY AERVGAGAPV YMAAVLEYLT
        70         80         90        100        110        120
AEILELAGNA ARDNKKTRII PRHLQLAIRN DEELNKLLGK VTIAQGGVLP NIQAVLLPKK
       130
TESHHKAKGK

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

6 N-termini - 5 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q6FI13-2-unknown	MSGRGK...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q6FI13-2-Acetylation	SGRGKQ...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q6FI13-22-unknown	AGLQFP...	22		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10356
Q6FI13-60-unknown	TAEILE...	60		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14598
Q6FI13-60-unknown	TAEILE...	60		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10357
Q6FI13-61-unknown	AEILEL...	61		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10358
Q6FI13-83-unknown	HLQLAI...	83		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10359

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SRSSRA	21	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10356
...VLEYLT	59	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14598
...VLEYLT	59	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10357
...LEYLTA	60	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10358
...RIIPRH	82	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10359
...KAKGK	130	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	21	SSRA.\|.AGLQ	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAM_HUMAN	59	EYLT.\|.TAEI	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAA_HUMAN	59	EYLT.\|.TAEI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAA_HUMAN	60	YLTA.\|.AEIL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAA_HUMAN	82	IPRH.\|.HLQL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)