Q9GZR7: ATP-dependent RNA helicase DDX24
Protein names | - ATP-dependent RNA helicase DDX24 - 3.6.4.13 - DEAD box protein 24 |
---|---|
Gene names | DDX24 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q9GZR7 |
13
N-termini
7
C-termini
6
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MKLKDTKSRP KQSSCGKFQT KGIKVVGKWK EVKIDPNMFA DGQMDDLVCF EELTDYQLVS
70 80 90 100 110 120
PAKNPSSLFS KEAPKRKAQA VSEEEEEEEG KSSSPKKKIK LKKSKNVATE GTSTQKEFEV
130 140 150 160 170 180
KDPELEAQGD DMVCDDPEAG EMTSENLVQT APKKKKNKGK KGLEPSQSTA AKVPKKAKTW
190 200 210 220 230 240
IPEVHDQKAD VSAWKDLFVP RPVLRALSFL GFSAPTPIQA LTLAPAIRDK LDILGAAETG
250 260 270 280 290 300
SGKTLAFAIP MIHAVLQWQK RNAAPPPSNT EAPPGETRTE AGAETRSPGK AEAESDALPD
310 320 330 340 350 360
DTVIESEALP SDIAAEARAK TGGTVSDQAL LFGDDDAGEG PSSLIREKPV PKQNENEEEN
370 380 390 400 410 420
LDKEQTGNLK QELDDKSATC KAYPKRPLLG LVLTPTRELA VQVKQHIDAV ARFTGIKTAI
430 440 450 460 470 480
LVGGMSTQKQ QRMLNRRPEI VVATPGRLWE LIKEKHYHLR NLRQLRCLVV DEADRMVEKG
490 500 510 520 530 540
HFAELSQLLE MLNDSQYNPK RQTLVFSATL TLVHQAPARI LHKKHTKKMD KTAKLDLLMQ
550 560 570 580 590 600
KIGMRGKPKV IDLTRNEATV ETLTETKIHC ETDEKDFYLY YFLMQYPGRS LVFANSISCI
610 620 630 640 650 660
KRLSGLLKVL DIMPLTLHAC MHQKQRLRNL EQFARLEDCV LLATDVAARG LDIPKVQHVI
670 680 690 700 710 720
HYQVPRTSEI YVHRSGRTAR ATNEGLSLML IGPEDVINFK KIYKTLKKDE DIPLFPVQTK
730 740 750 760 770 780
YMDVVKERIR LARQIEKSEY RNFQACLHNS WIEQAAAALE IELEEDMYKG GKADQQEERR
790 800 810 820 830 840
RQKQMKVLKK ELRHLLSQPL FTESQKTKYP TQSGKPPLLV SAPSKSESAL SCLSKQKKKK
850
TKKPKEPQPE QPQPSTSAN
Isoforms
- Isoform 2 of ATP-dependent RNA helicase DDX24Sequence View
10 20 30 40 50 60
MKLKDTKSRP KQSSCGKFQT KGIKVVGKWK EVKIDPNMFA DGQMDDLVCF EELTDYQLVS
70 80 90 100 110 120
PAKNPSSLFS KEAPKRKAQA VSEEEEEEEG KSSSPKKKIK LKKSKNVATE GTSTQKEFEV
130 140 150 160 170 180
KDPELEAQGD DMVCDDPEAG EMTSENLVQT APKKKKNKGK KGLEPSQSTA AKVPKKAKTW
190 200 210 220 230 240
IPEVHDQKAD VSAWKDLFVP RPVLRALSFL GFSAPTPIQA LTLAPAIRDK LDILGAAETG
250 260 270 280 290 300
SGKTLAFAIP MIHAVLQWQK RNAAPPPSNT EAPPGETRTE AGAETRSPGK AEAESDALPD
310 320 330 340 350 360
DTVIESEALP SDIAAEARAK TGGTVSDQAL LFGDDDAGEG PSSLIREKPV PKQNENEEEN
370 380 390 400 410 420
LDKEQTGNLK QELDDKSATC KAYPKRPLLG LVLTPTRELA VQVKQHIDAV ARFTGIKTAI
430 440 450 460 470 480
LVGGMSTQKQ QRMLNRRPEI VVATPGRLWE LIKEKHYHLR NLRQLRCLVV DEADRMVEKG
490 500 510 520 530 540
HFAELSQLLE MLNDSQYNPK RQTLVFSATL TLVHQAPARI LHKKHTKKMD KTAKLDLLMQ
550 560 570 580 590 600
KIGMRGKPKV IDLTRNEATV ETLTETKIHC ETDEKDFYLY YFLMQYPGRS LVFANSISCI
610 620 630 640 650 660
KRLSGLLKVL DIMPLTLHAC MHQKQRLRNL EQFARLEDCV LLATDVAARG LDIPKVQHVI
670 680 690 700 710 720
HYQVPRTSEI YVHRSGRTAR ATNEGLSLML IGPEDVINFK KIYKTLKKDE DIPLFPVQTK
730 740 750 760 770 780
YMDVVKERIR LARQIEKSEY RNFQACLHNS WIEQAAAALE IELEEDMYKG GKADQQEERR
790 800 810 820 830 840
RQKQMKVLKK ELRHLLSQPL FTESQKTKYP TQSGKPPLLV SAPSKSESAL SCLSKQKKKK
850
TKKPKEPQPE QPQPSTSAN
Protein Neighborhood
Domains & Features
13 N-termini - 7 C-termini - 6 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q9GZR7-1-unknown | MKLKDT... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
Q9GZR7-1-unknown | MKLKDT... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt72537 | |||
Q9GZR7-1-unknown | MKLKDT... | 1 | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345 | |||
Q9GZR7-1-unknown | MKLKDT... | 1 | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345 | |||
Q9GZR7-44-unknown | MDDLVC... | 44 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000452145 | |||
Q9GZR7-44-unknown | MDDLVC... | 44 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt131001 | |||
Q9GZR7-251-unknown | MIHAVL... | 251 | inferred from electronic annotation | unknown | Ensembl | inferred from ensembl protein ENSP00000440623 | |||
Q9GZR7-251-unknown | MIHAVL... | 251 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt130999 | |||
Q9GZR7-297- | ALPDDT... | 297 | Subtiligase Based Positive Selection | Wells | apoptotic_DB_Doxo | 23264352 | |||
Q9GZR7-297- | ALPDDT... | 297 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_bortezomib | 23264352 | |||
Q9GZR7-297- | ALPDDT... | 297 | Subtiligase Based Positive Selection | Wells | apoptotic_Jurkat_staurotrail | 23264352 | |||
Q9GZR7-297- | ALPDDT... | 297 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
Q9GZR7-297- | ALPDDT... | 297 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1SDBJurkat_Mix | 23264352 | |||
Q9GZR7-297- | ALPDDT... | 297 | Subtiligase Based Positive Selection | Wells | apoptosis_U266_bortezomib_induced | 23264352 | |||
Q9GZR7-297-unknown | ALPDDT... | 297 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt165205 | |||
Q9GZR7-308-unknown | ALPSDI... | 308 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13277 | |||
Q9GZR7-308-unknown | ALPSDI... | 308 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt148564 | |||
Q9GZR7-329-unknown | ALLFGD... | 329 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13279 | |||
Q9GZR7-329-unknown | ALLFGD... | 329 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt149224 | |||
Q9GZR7-332-unknown | FGDDDA... | 332 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14983 | |||
Q9GZR7-332-unknown | FGDDDA... | 332 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt149274 | |||
Q9GZR7-335-unknown | DDAGEG... | 335 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13281 | |||
Q9GZR7-335-unknown | DDAGEG... | 335 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt149357 | |||
Q9GZR7-467-unknown | CLVVDE... | 467 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10541 | |||
Q9GZR7-467-unknown | CLVVDE... | 467 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt152186 | |||
Q9GZR7-546-unknown | GKPKVI... | 546 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10543 | |||
Q9GZR7-546-unknown | GKPKVI... | 546 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt153309 | |||
Q9GZR7-807- | TKYPTQ... | 807 | Subtiligase Based Positive Selection | Wells | Jurkat_untreated | 23264352 | |||
Q9GZR7-807-unknown | TKYPTQ... | 807 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt169752 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...VIESEA | 307 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13277 | |||
...VIESEA | 307 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt131938 | |||
...TVSDQA | 328 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13279 | |||
...TVSDQA | 328 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt132609 | |||
...DQALLF | 331 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC14983 | |||
...DQALLF | 331 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt132660 | |||
...LLFGDD | 334 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC13281 | |||
...LLFGDD | 334 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt132741 | |||
...LRQLRC | 466 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10541 | |||
...LRQLRC | 466 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt135596 | |||
...KIGMRG | 545 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC10543 | |||
...KIGMRG | 545 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt136733 | |||
...STSAN | 859 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...STSAN | 859 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt68155 |
Cleavages
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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