Q9NP50: SIN3-HDAC complex-associated factor {ECO:0000312|HGNC:HGNC:30702}

General Information

Protein names	- SIN3-HDAC complex-associated factor {ECO:0000312\|HGNC:HGNC:30702} - Protein FAM60A - Tera protein homolog
Gene names	FAM60A
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q9NP50

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Protein FAM60A - Isoform 2 of SIN3-HDAC complex-associated factor

Sequence View

        10         20         30         40         50         60
MFGFHKPKMY RSIEGCCICR AKSSSSRFTD SKRYEKDFQS CFGLHETRSG DICNACVLLV
        70         80         90        100        110        120
KRWKKLPAGS KKNWNHVVDA RAGPSLKTTL KPKKVKTLSG NRIKSNQISK LQKEFKRHNS
       130        140        150        160        170        180
DAHSTTSSAS PAQSPCYSNQ SDDGSDTEMA SGSNRTPVFS FLDLTYWKRQ KICCGIIYKG
       190        200        210        220
RFGEVLIDTH LFKPCCSNKK AAAEKPEEQG PEPLPISTQE W         10         20         30         40         50         60
MFGFHKPKMY RSIEGCCICR AKSSSSRFTD SKRYEKDFQS CFGLHETRSG DICNACVLLV
        70         80         90        100        110        120
KRWKKLPAGS KKNWNHVVDA RAGPSLKTTL KPKKVKTLSG NRIKSNQISK LQKEFKRHNS
       130        140        150        160        170        180
DAHSTTSSAS PAQSPCYSNQ SDDGSDTEMA SGSNRTPVFS FLDLTYWKRQ KICCGIIYKG
       190        200        210        220
RFGEVLIDTH LFKPCCSNKK AAAEKPEEQG PEPLPISTQE W

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q9NP50-1-	MFGFHK...	1		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q9NP50-1-unknown	MFGFHK...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q9NP50-82-unknown	AGPSLK...	82	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10559
Q9NP50-149-unknown	MASGSN...	149	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt74640

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VVDARA	81	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10559
...STQEW	221	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...STQEW	221	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt70258

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	81	DARA.\|.AGPS	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)