P26373: 60S ribosomal protein L13

General Information

Protein names	- 60S ribosomal protein L13 - Breast basic conserved protein 1 - Large ribosomal subunit protein eL13 {ECO:0000303\|PubMed:24524803}
Gene names	RPL13
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P26373

22 N-termini

11 C-termini

9 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAPSRNGMVL KPHFHKDWQR RVATWFNQPA RKIRRRKARQ AKARRIAPRP ASGPIRPIVR
        70         80         90        100        110        120
CPTVRYHTKV RAGRGFSLEE LRVAGIHKKV ARTIGISVDP RRRNKSTESL QANVQRLKEY
       130        140        150        160        170        180
RSKLILFPRK PSAPKKGDSS AEELKLATQL TGPVMPVRNV YKKEKARVIT EEEKNFKAFA
       190        200        210
SLRMARANAR LFGIRAKRAK EAAEQDVEKK K

Isoforms

- Isoform 2 of 60S ribosomal protein L13

Sequence View

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Protein Neighborhood

Domains & Features

22 N-termini - 11 C-termini - 9 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P26373-1-unknown	MAPSRN...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P26373-1-unknown	MAPSRN...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt87815
P26373-12-unknown	PHFHKD...	12	inferred from electronic annotation	unknown	TISdb		inferred from TISdb
P26373-12-unknown	PHFHKD...	12	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt194939
P26373-22-	VATWFN...	22		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P26373-22-unknown	VATWFN...	22	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169588
P26373-106-unknown	STESLQ...	106	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10044
P26373-136-	KGDSSA...	136		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P26373-136-	KGDSSA...	136		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P26373-136-unknown	KGDSSA...	136	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt164868
P26373-139-unknown	SSAEEL...	139	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11373
P26373-139-unknown	SSAEEL...	139	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt197536
P26373-142-unknown	EELKLA...	142	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18980
P26373-142-unknown	EELKLA...	142	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt197555
P26373-145-unknown	KLATQL...	145		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P26373-145-unknown	KLATQL...	145	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160123
P26373-145-	KLATQL...	145		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P26373-146-unknown	LATQLT...	146		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P26373-146-unknown	LATQLT...	146	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160125
P26373-146-	LATQLT...	146		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P26373-146-	LATQLT...	146		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
P26373-147-unknown	ATQLTG...	147		unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P26373-147-unknown	ATQLTG...	147	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160121
P26373-147-	ATQLTG...	147		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P26373-147-	ATQLTG...	147		Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
P26373-149-unknown	QLTGPV...	149	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14049
P26373-149-unknown	QLTGPV...	149	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt142511
P26373-150-unknown	LTGPVM...	150	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3729
P26373-150-unknown	LTGPVM...	150	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt142555
P26373-159-unknown	NVYKKE...	159	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14051
P26373-159-unknown	NVYKKE...	159	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143090
P26373-160-unknown	VYKKEK...	160	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14053
P26373-160-unknown	VYKKEK...	160	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143146
P26373-162-unknown	KKEKAR...	162	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14055
P26373-162-unknown	KKEKAR...	162	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt143253
P26373-168-	VITEEE...	168		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P26373-168-unknown	VITEEE...	168	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt169590

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...RRRNKS	105	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10044
...PKKGDS	138	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11373
...GDSSAE	141	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC18980
...LKLATQ	148	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14049
...KLATQL	149	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC3729
...VMPVRN	158	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14051
...VMPVRN	158	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt126308
...MPVRNV	159	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14053
...MPVRNV	159	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt126368
...VRNVYK	161	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14055
...VRNVYK	161	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt126483
...AAEQDV	206	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11374
...AAEQDV	206	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt128420
...VEKKK	211	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...VEKKK	211	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt83433
...VEKKK	211		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...VEKKK	211		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...VEKKK	211		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...VEKKK	211		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	105	RNKS.\|.STES	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAB_HUMAN	138	KGDS.\|.SSAE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
MEP1B_HUMAN	141	SSAE.\|.EELK	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAM_HUMAN	148	LATQ.\|.QLTG	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
CATB_HUMAN	149	ATQL.\|.LTGP	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAM_HUMAN	158	PVRN.\|.NVYK	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	159	VRNV.\|.VYKK	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAM_HUMAN	161	NVYK.\|.KKEK	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAB_HUMAN	206	EQDV.\|.VEKK	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)