P33778: Histone H2B type 1-B

General Information

Protein names	- Histone H2B type 1-B - Histone H2B.1 - Histone H2B.f - H2B/f
Gene names	HIST1H2BB
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P33778

6 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPEPSKSAPA PKKGSKKAIT KAQKKDGKKR KRSRKESYSI YVYKVLKQVH PDTGISSKAM
        70         80         90        100        110        120
GIMNSFVNDI FERIAGEASR LAHYNKRSTI TSREIQTAVR LLLPGELAKH AVSEGTKAVT

KYTSSK

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P33778-2-unknown	MPEPSK...	1		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P33778-2-unknown	MPEPSK...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P33778-2-	PEPSKS...	2			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P33778-2-	PEPSKS...	2			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P33778-2-Acetylation	PEPSKS...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P33778-2-Acetylation	PEPSKS...	2	acetylation-	inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P33778-22-unknown	AQKKDG...	22		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10060
P33778-53-unknown	TGISSK...	53		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11446
P33778-59-unknown	AMGIMN...	59		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10061
P33778-59-unknown	AMGIMN...	59		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P33778-59-unknown	AMGIMN...	59		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KAITKA	21	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10060
...QVHPDT	52	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11446
...GISSKA	58	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10061
...YTSSK	126	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	21	ITKA.\|.AQKK	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAB_HUMAN	52	HPDT.\|.TGIS	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,
GRAA_HUMAN	58	SSKA.\|.AMGI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)