P60866: 40S ribosomal protein S20

General Information

Protein names	- 40S ribosomal protein S20 - Small ribosomal subunit protein uS10 {ECO:0000303\|PubMed:24524803}
Gene names	RPS20
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P60866

11 N-termini

4 C-termini

5 Cleavages

0 Substrates

Sequence

10 20 30 40 50 60
MAFKDTGKTP VEPEVAIHRI RITLTSRNVK SLEKVCADLI RGAKEKNLKV KGPVRMPTKT
70 80 90 100 110
LRITTRKTPC GEGSKTWDRF QMRIHKRLID LHSPSEIVKQ ITSISIEPGV EVEVTIADA

Isoforms

- Isoform 2 of 40S ribosomal protein S20

Sequence View

10 20 30 40 50 60
MAFKDTGKTP VEPEVAIHRI RITLTSRNVK SLEKVCADLI RGAKEKNLKV KGPVRMPTKT
70 80 90 100 110
LRITTRKTPC GEGSKTWDRF QMRIHKRLID LHSPSEIVKQ ITSISIEPGV EVEVTIADA

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

11 N-termini - 4 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P60866-2-unknown	MAFKDT...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P60866-2-unknown	MAFKDT...	1			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P60866-2-unknown	MAFKDT...	1			unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P60866-2-unknown	MAFKDT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt168431
P60866-1-unknown	MAFKDT...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt88259
P60866-2-Acetylation	AFKDTG...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P60866-2-Acetylation	AFKDTG...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P60866-2-Acetylation	AFKDTG...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P60866-2-Acetylation	AFKDTG...	2	acetylation-		N-TAILS		Overall Laboratory	Lange_Huesgen_et_al-RBC
P60866-2-Acetylation	AFKDTG...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt110291
P60866-2-	AFKDTG...	2			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P60866-2-	AFKDTG...	2			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P60866-2-	AFKDTG...	2			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P60866-2-	AFKDTG...	2			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
P60866-2-	AFKDTG...	2			Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
P60866-2-	AFKDTG...	2			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P60866-2-	AFKDTG...	2			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
P60866-4-unknown	KDTGKT...	4		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt177375
P60866-4-	KDTGKT...	4			Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
P60866-5-unknown	DTGKTP...	5		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10115
P60866-5-unknown	DTGKTP...	5			unknown			Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P60866-5-unknown	DTGKTP...	5		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt160207
P60866-5-	DTGKTP...	5			Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
P60866-5-	DTGKTP...	5			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
P60866-5-	DTGKTP...	5			Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352
P60866-5-	DTGKTP...	5			Subtiligase Based Positive Selection		Wells	THP_untreated	23264352
P60866-9-unknown	TPVEPE...	9		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC19235
P60866-9-unknown	TPVEPE...	9		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC17762
P60866-9-unknown	TPVEPE...	9		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt194823
P60866-9-unknown	TPVEPE...	9		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P60866-9-unknown	TPVEPE...	9		inferred from similarity	unknown	UniProtKB		inferred from uniprot (by similarity)
P60866-39-unknown	LIRGAK...	39		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11741
P60866-39-unknown	LIRGAK...	39		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt138285
P60866-50-unknown	VKGPVR...	50		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14230
P60866-50-unknown	VKGPVR...	50		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt139191

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KDTGKT	8	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19235
...KDTGKT	8	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC17762
...KVCADL	38	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11741
...KVCADL	38	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt121317
...EKNLKV	49	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14230
...EKNLKV	49	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt122266
...TIADA	119	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	4	AFKD.\|.DTGK	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
MEP1B_HUMAN	8	TGKT.\|.TPVE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
MEP1A_HUMAN	8	TGKT.\|.TPVE	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
GRAB_HUMAN	38	CADL.\|.LIRG	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAM_HUMAN	49	NLKV.\|.VKGP	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)