Q99848: Probable rRNA-processing protein EBP2

General Information

Protein names	- Probable rRNA-processing protein EBP2 - EBNA1-binding protein 2 - Nucleolar protein p40
Gene names	EBNA1BP2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q99848

13 N-termini

8 C-termini

7 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MDTPPLSDSE SESDESLVTD RELQDAFSRG LLKPGLNVVL EGPKKAVNDV NGLKQCLAEF
        70         80         90        100        110        120
KRDLEWVERL DVTLGPVPEI GGSEAPAPQN KDQKAVDPED DFQREMSFYR QAQAAVLAVL
       130        140        150        160        170        180
PRLHQLKVPT KRPTDYFAEM AKSDLQMQKI RQKLQTKQAA MERSEKAKQL RALRKYGKKV
       190        200        210        220        230        240
QTEVLQKRQQ EKAHMMNAIK KYQKGFSDKL DFLEGDQKPL AQRKKAGAKG QQMRKGPSAK
       250        260        270        280        290        300
RRYKNQKFGF GGKKKGSKWN TRESYDDVSS FRAKTAHGRG LKRPGKKGSN KRPGKRTREK

MKNRTH

Isoforms

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

13 N-termini - 8 C-termini - 7 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q99848-1-Acetylation	MDTPPL...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q99848-5-unknown	PLSDSE...	5		inferred from electronic annotation	unknown	TISdb		inferred from TISdb
Q99848-22-unknown	ELQDAF...	22		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10496
Q99848-30-	GLLKPG...	30			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q99848-36-unknown	LNVVLE...	36		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC4227
Q99848-82-unknown	GSEAPA...	82		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC8047
Q99848-84-unknown	EAPAPQ...	84		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13149
Q99848-92-unknown	DQKAVD...	92		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10497
Q99848-95-	AVDPED...	95			Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q99848-164-unknown	SEKAKQ...	164		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10498
Q99848-212-	FLEGDQ...	212			Subtiligase Based Positive Selection		Wells	apoptotic_DB_Doxo	23264352
Q99848-212-	FLEGDQ...	212			Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q99848-212-	FLEGDQ...	212			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352
Q99848-212-	FLEGDQ...	212			Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352
Q99848-217-unknown	QKPLAQ...	217		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC13150
Q99848-248-	FGFGGK...	248			Subtiligase Based Positive Selection		Wells	apoptotic_RPMI_Dox	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...LVTDRE	21	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10496
...LLKPGL	35	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC4227
...VPEIGG	81	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC8047
...EIGGSE	83	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13149
...APQNKD	91	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10497
...AAMERS	163	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10498
...FLEGDQ	216	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC13150
...KNRTH	306	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	21	TDRE.\|.ELQD	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
CATB_HUMAN	35	KPGL.\|.LNVV	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
CATS_HUMAN	81	EIGG.\|.GSEA	inferred from experiment	unknown	MEROPS	Schilling O	Biniossek ML et al.:Proteomic identification of pro... (C01.060)	21967108,
GRAB_HUMAN	83	GGSE.\|.EAPA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAA_HUMAN	91	QNKD.\|.DQKA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAA_HUMAN	163	MERS.\|.SEKA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAB_HUMAN	216	EGDQ.\|.QKPL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)