Q13243: Serine/arginine-rich splicing factor 5

General Information

Protein names	- Serine/arginine-rich splicing factor 5 - Delayed-early protein HRS - Pre-mRNA-splicing factor SRP40 - Splicing factor, arginine/serine-rich 5
Gene names	SRSF5
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q13243

4 N-termini

2 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform SRP40-2 of Serine/arginine-rich splicing factor 5 - Isoform SRP40-4 of Serine/arginine-rich splicing factor 5

Sequence View

        10         20         30         40         50         60
MSGCRVFIGR LNPAAREKDV ERFFKGYGRI RDIDLKRGFG FVEFEDPRDA DDAVYELDGK
        70         80         90        100        110        120
ELCSERVTIE HARARSRGGR GRGRYSDRFS SRRPRNDRRN APPVRTENRL IVENLSSRVS
       130        140        150        160        170        180
WQDLKDFMRQ AGEVTFADAH RPKLNEGVVE FASYGDLKNA IEKLSGKEIN GRKIKLIEGS
       190        200        210        220        230        240
KRHSRSRSRS RSRTRSSSRS RSRSRSRSRK SYSRSRSRSR SRSRSKSRSV SRSPVPEKSQ
       250        260        270
KRGSSSRSKS PASVDRQRSR SRSRSRSVDS GN         10         20         30         40         50         60
MSGCRVFIGR LNPAAREKDV ERFFKGYGRI RDIDLKRGFG FVEFEDPRDA DDAVYELDGK
        70         80         90        100        110        120
ELCSERVTIE HARARSRGGR GRGRYSDRFS SRRPRNDRRN APPVRTENRL IVENLSSRVS
       130        140        150        160        170        180
WQDLKDFMRQ AGEVTFADAH RPKLNEGVVE FASYGDLKNA IEKLSGKEIN GRKIKLIEGS
       190        200        210        220        230        240
KRHSRSRSRS RSRTRSSSRS RSRSRSRSRK SYSRSRSRSR SRSRSKSRSV SRSPVPEKSQ
       250        260        270
KRGSSSRSKS PASVDRQRSR SRSRSRSVDS GN

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Protease Assignment Confidence:

Evidence Names:

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Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q13243-1-unknown	MSGCRV...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q13243-1-unknown	MSGCRV...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90737
Q13243-1-unknown	MSGCRV...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90738
Q13243-38-unknown	GFGFVE...	38	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt171894
Q13243-38-	GFGFVE...	38		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_staurotrail	23264352
Q13243-38-	GFGFVE...	38		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
Q13243-38-	GFGFVE...	38		Subtiligase Based Positive Selection		Wells	MM1SDBJurkat_Untreated	23264352
Q13243-110-unknown	LIVENL...	110	inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10221
Q13243-110-unknown	LIVENL...	110	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt142784

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RTENRL	109	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10221
...RTENRL	109	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt125988
...VDSGN	272	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...VDSGN	272	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt86356

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	109	ENRL.\|.LIVE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)