P55081: Microfibrillar-associated protein 1 {ECO:0000312|HGNC:HGNC:7032}

General Information

Protein names	- Microfibrillar-associated protein 1 {ECO:0000312\|HGNC:HGNC:7032} - Spliceosome B complex protein MFAP1 {ECO:0000303\|PubMed:28781166}
Gene names	MFAP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P55081

7 N-termini

5 C-termini

4 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSVPSALMKQ PPIQSTAGAV PVRNEKGEIS MEKVKVKRYV SGKRPDYAPM ESSDEEDEEF
        70         80         90        100        110        120
QFIKKAKEQE AEPEEQEEDS SSDPRLRRLQ NRISEDVEER LARHRKIVEP EVVGESDSEV
       130        140        150        160        170        180
EGDAWRMERE DSSEEEEEEI DDEEIERRRG MMRQRAQERK NEEMEVMEVE DEGRSGEESE
       190        200        210        220        230        240
SESEYEEYTD SEDEMEPRLK PVFIRKKDRV TVQEREAEAL KQKELEQEAK RMAEERRKYT
       250        260        270        280        290        300
LKIVEEETKK ELEENKRSLA ALDALNTDDE NDEEEYEAWK VRELKRIKRD REDREALEKE
       310        320        330        340        350        360
KAEIERMRNL TEEERRAELR ANGKVITNKA VKGKYKFLQK YYHRGAFFMD EDEEVYKRDF
       370        380        390        400        410        420
SAPTLEDHFN KTILPKVMQV KNFGRSGRTK YTHLVDQDTT SFDSAWGQES AQNTKFFKQK
       430
AAGVRDVFER PSAKKRKTT

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

7 N-termini - 5 C-termini - 4 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P55081-2-unknown	MSVPSA...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P55081-2-Acetylation	SVPSAL...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P55081-2-Acetylation	SVPSAL...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P55081-2-Acetylation	SVPSAL...	2	acetylation-		other		CNRS/ISV	Large_scale_NTA_Human
P55081-2-Acetylation	SVPSAL...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P55081-93-unknown	ISEDVE...	93		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC10099
P55081-116-unknown	SDSEVE...	116		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11695
P55081-242-unknown	KIVEEE...	242		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC14212
P55081-264-	ALNTDD...	264			Subtiligase Based Positive Selection		Wells	apoptotic_MM1SDBJurkat_Mix	23264352
P55081-269-unknown	DENDEE...	269		inferred from cleavage	unknown	TopFIND		Inferred from cleavage TC11696

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RLQNRI	92	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10099
...EVVGES	115	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11695
...RKYTLK	241	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14212
...ALNTDD	268	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC11696
...KRKTT	439	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	92	QNRI.\|.ISED	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAB_HUMAN	115	VGES.\|.SDSE	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Complementary positional proteo... (M14.017)	20526345,
GRAM_HUMAN	241	YTLK.\|.KIVE	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAB_HUMAN	268	NTDD.\|.DEND	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:Analysis of protein processing ... (S01.010)	18836177,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)