Q6S8J3: POTE ankyrin domain family member E

General Information

Protein names	- POTE ankyrin domain family member E - ANKRD26-like family C member 1A - Prostate, ovary, testis-expressed protein on chromosome 2 - POTE-2
Gene names	POTEE
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q6S8J3

11 N-termini

11 C-termini

10 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of POTE ankyrin domain family member E - Isoform 3 of POTE ankyrin domain family member E

Sequence View

        10         20         30         40         50         60
MVVEVDSMPA ASSVKKPFGL RSKMGKWCCR CFPCYRESGK SNVGTSGDHD DSAMKTLRSK
        70         80         90        100        110        120
MGKWCHHCFP CCRGSGKSNV GASGDHDDSA MKTLRNKMGK WCCHCFPCCR GSGKSKVGAW
       130        140        150        160        170        180
GDYDDSAFME PRYHVRGEDL DKLHRAAWWG KVPRKDLIVM LRDTDVNKKD KQKRTALHLA
       190        200        210        220        230        240
SANGNSEVVK LLLDRRCQLN VLDNKKRTAL IKAVQCQEDE CALMLLEHGT DPNIPDEYGN
       250        260        270        280        290        300
TTLHYAIYNE DKLMAKALLL YGADIESKNK HGLTPLLLGV HEQKQQVVKF LIKKKANLNA
       310        320        330        340        350        360
LDRYGRTALI LAVCCGSASI VSLLLEQNID VSSQDLSGQT AREYAVSSHH HVICQLLSDY
       370        380        390        400        410        420
KEKQMLKISS ENSNPEQELK LTSEEESQRF KGSENSQPEK MSQELEINKD GDREVEEEMK
       430        440        450        460        470        480
KHESNNVGLL ENLTNGVTAG NGDNGLIPQR KSRTPENQQF PDNESEEYHR ICELLSDYKE
       490        500        510        520        530        540
KQMPKYSSEN SNPEQDLKLT SEEESQRLKG SENGQPEKRS QEPEINKDGD RELENFMAIE
       550        560        570        580        590        600
EMKKHGSTHV GFPENLTNGA TAGNGDDGLI PPRKSRTPES QQFPDTENEE YHSDEQNDTQ
       610        620        630        640        650        660
KQFCEEQNTG ILHDEILIHE EKQIEVVEKM NSELSLSCKK EKDVLHENST LREEIAMLRL
       670        680        690        700        710        720
ELDTMKHQSQ LREKKYLEDI ESVKKKNDNL LKALQLNELT MDDDTAVLVI DNGSGMCKAG
       730        740        750        760        770        780
FAGDDAPRAV FPSIVGRPRQ QGMMGGMHQK ESYVGKEAQS KRGILTLKYP MEHGIITNWD
       790        800        810        820        830        840
DMEKIWHHTF YNELRVAPEE HPILLTEAPL NPKANREKMT QIMFETFNTP AMYVAIQAVP
       850        860        870        880        890        900
SLYTSGRTTG IVMDSGDGVT HTVPIYEGNA LPHATLRLDL AGRELPDYLM KILTERGYRF
       910        920        930        940        950        960
TTMAEREIVR DIKEKLCYVA LDFEQEMATA ASSSSLEKSY ELPDGQVITI GNERFRCPEA
       970        980        990       1000       1010       1020
LFQPCFLGME SCGIHETTFN SIMKSDVDIR KDLYTNTVLS GGTTMYPGMA HRMQKEIAAL
      1030       1040       1050       1060       1070
APSMMKIRII APPKRKYSVW VGGSILASLS TFQQMWISKQ EYDESGPSIV HRKCF         10         20         30         40         50         60
MVVEVDSMPA ASSVKKPFGL RSKMGKWCCR CFPCYRESGK SNVGTSGDHD DSAMKTLRSK
        70         80         90        100        110        120
MGKWCHHCFP CCRGSGKSNV GASGDHDDSA MKTLRNKMGK WCCHCFPCCR GSGKSKVGAW
       130        140        150        160        170        180
GDYDDSAFME PRYHVRGEDL DKLHRAAWWG KVPRKDLIVM LRDTDVNKKD KQKRTALHLA
       190        200        210        220        230        240
SANGNSEVVK LLLDRRCQLN VLDNKKRTAL IKAVQCQEDE CALMLLEHGT DPNIPDEYGN
       250        260        270        280        290        300
TTLHYAIYNE DKLMAKALLL YGADIESKNK HGLTPLLLGV HEQKQQVVKF LIKKKANLNA
       310        320        330        340        350        360
LDRYGRTALI LAVCCGSASI VSLLLEQNID VSSQDLSGQT AREYAVSSHH HVICQLLSDY
       370        380        390        400        410        420
KEKQMLKISS ENSNPEQELK LTSEEESQRF KGSENSQPEK MSQELEINKD GDREVEEEMK
       430        440        450        460        470        480
KHESNNVGLL ENLTNGVTAG NGDNGLIPQR KSRTPENQQF PDNESEEYHR ICELLSDYKE
       490        500        510        520        530        540
KQMPKYSSEN SNPEQDLKLT SEEESQRLKG SENGQPEKRS QEPEINKDGD RELENFMAIE
       550        560        570        580        590        600
EMKKHGSTHV GFPENLTNGA TAGNGDDGLI PPRKSRTPES QQFPDTENEE YHSDEQNDTQ
       610        620        630        640        650        660
KQFCEEQNTG ILHDEILIHE EKQIEVVEKM NSELSLSCKK EKDVLHENST LREEIAMLRL
       670        680        690        700        710        720
ELDTMKHQSQ LREKKYLEDI ESVKKKNDNL LKALQLNELT MDDDTAVLVI DNGSGMCKAG
       730        740        750        760        770        780
FAGDDAPRAV FPSIVGRPRQ QGMMGGMHQK ESYVGKEAQS KRGILTLKYP MEHGIITNWD
       790        800        810        820        830        840
DMEKIWHHTF YNELRVAPEE HPILLTEAPL NPKANREKMT QIMFETFNTP AMYVAIQAVP
       850        860        870        880        890        900
SLYTSGRTTG IVMDSGDGVT HTVPIYEGNA LPHATLRLDL AGRELPDYLM KILTERGYRF
       910        920        930        940        950        960
TTMAEREIVR DIKEKLCYVA LDFEQEMATA ASSSSLEKSY ELPDGQVITI GNERFRCPEA
       970        980        990       1000       1010       1020
LFQPCFLGME SCGIHETTFN SIMKSDVDIR KDLYTNTVLS GGTTMYPGMA HRMQKEIAAL
      1030       1040       1050       1060       1070
APSMMKIRII APPKRKYSVW VGGSILASLS TFQQMWISKQ EYDESGPSIV HRKCF

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

11 N-termini - 11 C-termini - 10 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q6S8J3-1-unknown	MVVEVD...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q6S8J3-1-unknown	MVVEVD...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85817
Q6S8J3-1-unknown	MVVEVD...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt85818
Q6S8J3-709-unknown	VIDNGS...	709	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14631
Q6S8J3-712-unknown	NGSGMC...	712	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2257
Q6S8J3-718-unknown	KAGFAG...	718	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15458
Q6S8J3-719-unknown	AGFAGD...	719	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10368
Q6S8J3-806-unknown	TEAPLN...	806	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15459
Q6S8J3-807-unknown	EAPLNP...	807	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15460
Q6S8J3-917-unknown	CYVALD...	917	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14632
Q6S8J3-920-unknown	ALDFEQ...	920	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15461
Q6S8J3-926-unknown	EMATAA...	926	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19643
Q6S8J3-945-unknown	GQVITI...	945	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2258

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...DTAVLV	708	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14631
...VLVIDN	711	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2257
...GSGMCK	717	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15458
...SGMCKA	718	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10368
...HPILLT	805	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15459
...PILLTE	806	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15460
...IKEKLC	916	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14632
...KLCYVA	919	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC15461
...LDFEQE	925	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC19643
...YELPDG	944	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC2258
...HRKCF	1075	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAM_HUMAN	708	AVLV.\|.VIDN	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
CASP3_HUMAN	711	VIDN.\|.NGSG	inferred from experiment	unknown	MEROPS	Vandenabeele P	Demon D et al.:Proteome-wide substrate analysi... (C14.003)	19759058,
HTRA2_HUMAN	717	GMCK.\|.KAGF	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
GRAA_HUMAN	718	MCKA.\|.AGFA	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
HTRA2_HUMAN	805	ILLT.\|.TEAP	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
HTRA2_HUMAN	806	LLTE.\|.EAPL	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
GRAM_HUMAN	916	EKLC.\|.CYVA	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
HTRA2_HUMAN	919	CYVA.\|.ALDF	inferred from experiment	unknown	MEROPS	Vandenabeele P	Vande Walle L et al.:Proteome-wide Identification of... (S01.278)	17266347,
MEP1B_HUMAN	925	FEQE.\|.EMAT	inferred from experiment	unknown	MEROPS	Overall CM	Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002)	21693781,
CASP3_HUMAN	944	LPDG.\|.GQVI	inferred from experiment	unknown	MEROPS	Vandenabeele P	Demon D et al.:Proteome-wide substrate analysi... (C14.003)	19759058,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)