Q93077: Histone H2A type 1-C

General Information

Protein names	- Histone H2A type 1-C - Histone H2A/l
Gene names	HIST1H2AC
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q93077

6 N-termini

5 C-termini

5 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSGRGKQGGK ARAKAKSRSS RAGLQFPVGR VHRLLRKGNY AERVGAGAPV YLAAVLEYLT
        70         80         90        100        110        120
AEILELAGNA ARDNKKTRII PRHLQLAIRN DEELNKLLGR VTIAQGGVLP NIQAVLLPKK
       130
TESHHKAKGK

Isoforms

Sequence View

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Protein Neighborhood

Domains & Features

6 N-termini - 5 C-termini - 5 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q93077-2-unknown	MSGRGK...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q93077-2-unknown	MSGRGK...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q93077-2-Acetylation	SGRGKQ...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q93077-2-Acetylation	SGRGKQ...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q93077-22-unknown	AGLQFP...	22		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10469
Q93077-60-unknown	TAEILE...	60		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14816
Q93077-60-unknown	TAEILE...	60		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10470
Q93077-61-unknown	AEILEL...	61		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10471
Q93077-83-unknown	HLQLAI...	83		inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10472

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...SRSSRA	21	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10469
...VLEYLT	59	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC14816
...VLEYLT	59	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10470
...LEYLTA	60	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10471
...RIIPRH	82	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC10472
...KAKGK	130	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
GRAA_HUMAN	21	SSRA.\|.AGLQ	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAM_HUMAN	59	EYLT.\|.TAEI	inferred from experiment	unknown	MEROPS	Bovenschen N	de Poot SA et al.:Human and mouse granzyme M disp... (S01.139)	21564021,
GRAA_HUMAN	59	EYLT.\|.TAEI	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAA_HUMAN	60	YLTA.\|.AEIL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,
GRAA_HUMAN	82	IPRH.\|.HLQL	inferred from experiment	unknown	MEROPS	Gevaert K	Van Damme P et al.:The substrate specificity profi... (S01.135)	20536382,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)